Development Level

Tchem 17 | 1,598
Tbio 2 | 11,445
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Comple... 6 | 37
Kinase: IDG Consortium (Target... 6 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
preweaning lethality, incomple... 2 | 499
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal neural tube closure 1 | 46
abnormal skin morphology 1 | 50
decreased circulating magnesiu... 1 | 13
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
female infertility 1 | 60
hyperactivity 1 | 148
increased heart rate 1 | 23
increased startle reflex 1 | 112
male infertility 1 | 123
microphthalmia 1 | 26
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74

Disease

medulloblastoma, large-cell 14 | 6,241
Carcinoma 12 | 11,493
ovarian cancer 11 | 8,520
glioblastoma 9 | 5,792
malignant mesothelioma 9 | 3,232
osteosarcoma 9 | 7,950
psoriasis 9 | 6,694
Cancer 8 | 2,499
adult high grade glioma 8 | 3,801
atypical teratoid / rhabdoid tumor 8 | 5,112
ependymoma 8 | 4,679
group 3 medulloblastoma 7 | 4,104
Astrocytoma, Pilocytic 6 | 3,081
lung cancer 6 | 4,740
primitive neuroectodermal tumor 6 | 3,035
Breast cancer 5 | 3,578
Pick disease 5 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
tuberculosis 5 | 2,010
Rheumatoid arthritis 4 | 1,191
colon cancer 4 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
oligodendroglioma 4 | 2,850
Melanoma 3 | 711
acute myeloid leukemia 3 | 783
adrenocortical carcinoma 3 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
subependymal giant cell astrocytoma 3 | 2,287
Acquired metabolic disease 2 | 336
Agenesis of corpus callosum 2 | 83
Autosomal recessive predisposition 2 | 1,442
Brain Stem Neoplasms 2 | 4
Carcinoma, Hepatocellular 2 | 228
Chronic myeloid leukemia 2 | 12
Cognitive delay 2 | 608
Congenital hereditary endothelial dystrophy of cornea 2 | 8
Familial hemophagocytic lymphohistiocytosis 3 2 | 5
Gaucher disease type 3 2 | 67
Global developmental delay 2 | 608
Hormone receptor positive malignant neoplasm of breast 2 | 10
Human epidermal growth factor 2 negative carcinoma of breast 2 | 3
Intellectual disability 2 | 1,016
Kidney cancer 2 | 2,613
Liver carcinoma 2 | 240
Mammary Neoplasms, Experimental 2 | 154
Mental and motor retardation 2 | 608
Philadelphia chromosome-positive acute lymphoblastic leukemia 2 | 47
Schizophrenia 2 | 1,160
Small head 2 | 374
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
cystic fibrosis 2 | 1,696
group 4 medulloblastoma 2 | 1,855
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
ulcerative colitis 2 | 1,819
Absent reflex 1 | 92
Absent tendon reflex 1 | 92
Alcoholic Intoxication, Chronic 1 | 289
Amyotrophic lateral sclerosis 1 | 451
Animal Mammary Neoplasms 1 | 136
Arthrogryposis 1 | 54
Brain disease 1 | 96
Cardiovascular system disease 1 | 246
Clenched hands 1 | 6
Cortical gyral simplification 1 | 19
Dementia 1 | 175
Dilated ventricles (finding) 1 | 121
Freckles 1 | 33
Gaucher disease type 1 1 | 180
Hirsutism 1 | 47
Hyperreflexia 1 | 209
Lipoma 1 | 32
Liver Cirrhosis, Experimental 1 | 769
Lymphatic Diseases 1 | 14
Lymphedema 1 | 42
Mammary Neoplasms, Animal 1 | 136
Melanocytic nevus 1 | 43
Mesothelioma, Malignant 1 | 105
Microcephaly 1 | 166
Neurodegenerative disease 1 | 414
Pachygyria 1 | 41
Prenatal onset 1 | 139
Reflex, Deep Tendon, Absent 1 | 92
Severe mental retardation (I.Q. 20-34) 1 | 99
Thin upper lip vermilion 1 | 67
Tick infestation 1 | 17
Toxic encephalopathy 1 | 141
adrenocortical adenoma 1 | 131
atypical teratoid/rhabdoid tumor 1 | 357
posterior fossa group B ependymoma 1 | 416
sarcoidosis 1 | 370

Tissue

Blood and immune system 20 | 16,909
Cardiovascular System 20 | 15,192
Digestive Tract 20 | 17,369
Endocrine System 20 | 18,159
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Male tissues 20 | 17,142
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678

Target Family

Kinase 21 | 634

DTO Protein Class (3)

CDK family 21 | 21
STE20 family 31 | 31
CAMKL family 22 | 22
MAPK family 15 | 15
EPH family 14 | 14
C-C chemokine receptor 13 | 13
STKR family 12 | 12
NEK family 11 | 11
PI3-PI4 kinase family 11 | 11
SRC family 11 | 11
DYRK family 10 | 10
MLK family 10 | 10
P2Y receptor 10 | 10
PKC family 9 | 9
DMPK family 8 | 8
PIKK family 8 | 8
RSK family 8 | 8
STE11 family 8 | 8
CK1 family 7 | 7
CLK family 7 | 7
GRK family 7 | 7
RAF family 7 | 7
STE7 family 7 | 7
Alpha adrenoceptor 6 | 6
MAST family 6 | 6
RGC family 6 | 6
SCY1 family 6 | 6
TEC family 6 | 6
5-HT1 receptor 5 | 5
5-HT3 receptor sub-subfamily 5 | 5
ABC1 family 5 | 5
Alpha family 5 | 5
CAMK1 family 5 | 5
CDKL family 5 | 5
DAPK family 5 | 5
MAPKAPK family 5 | 5
MLCK family 5 | 5
PDGFR family 5 | 5
PDHK family 5 | 5
PKA family 5 | 5
PLK family 5 | 5
RIPK family 5 | 5
TSSK family 5 | 5
ULK family 5 | 5
Adenylate kinase family 4 | 4
C-X-C chemokine receptor 4 | 4
CAMK2 family 4 | 4
CK2 family 4 | 4
EGFR family 4 | 4
FGFR family 4 | 4
Hexokinase family 4 | 4
IKK family 4 | 4
IRAK family 4 | 4
JAKA family 4 | 4
LISK family 4 | 4
NAK family 4 | 4
NDR family 4 | 4
PEK family 4 | 4
PIM family 4 | 4
TRIO family 4 | 4
WNK family 4 | 4
5-HT2 receptor 3 | 3
AKT family 3 | 3
AUR family 3 | 3
AXL family 3 | 3
Beta adrenoceptor 3 | 3
DCAMKL family 3 | 3
DCK-DGK family 3 | 3
Diacylglycerol kinase family 3 | 3
INSR family 3 | 3
Inositol phosphokinase (IPK) f... 3 | 3
LMR family 3 | 3
MET family 3 | 3
NKF1 family 3 | 3
Other-UNIQUE family 3 | 3
PKD family 3 | 3
PKN family 3 | 3
RCK family 3 | 3
RIO family 3 | 3
SGK family 3 | 3
SRPK family 3 | 3
TRBL family 3 | 3
TRK family 3 | 3
Type II pantothenate kinase fa... 3 | 3
VEGFR family 3 | 3
VRK family 3 | 3
WEE family 3 | 3
YANK family 3 | 3
ABL family 2 | 2
ACK family 2 | 2
Alpha-7-CHRNA7 sub-subfamily 2 | 2
BUB family 2 | 2
CAMK-UNIQUE family 2 | 2
CSK family 2 | 2
FGGY kinase family 2 | 2
NRBP family 2 | 2
STE-UNIQUE family 2 | 2
TIE family 2 | 2
TRPM2 sub-subfamily 2 | 2
TTBK family 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cyclin-dependent kinase 12 CDK12 Tchem Kinase -1.38476 29.4 157
Cyclin-dependent kinase 20 CDK20 Tbio Kinase -1.82269 67.7 248
Cyclin-dependent kinase 11B CDK11B Tchem Kinase -1.15493 16.6 0
Cyclin-dependent kinase 15 CDK15 Tchem Kinase 0.63 0.78 158
Cyclin-dependent kinase 18 CDK18 Tchem Kinase -1.12583 12.1 147
Cyclin-dependent kinase 14 CDK14 Tchem Kinase -1.36348 25.4 193
Cyclin-dependent kinase 19 CDK19 Tchem Kinase -1.35400 18.0 154
Cyclin-dependent kinase 3 CDK3 Tchem Kinase -1.44123 25.3 65
Cyclin-dependent-like kinase 5 CDK5 Tchem Kinase -3.06393 1238.4 694
Cyclin-dependent kinase 16 CDK16 Tchem Kinase -1.47874 34.2 153