Development Level

Tchem 19 | 1,598
Tbio 3 | 11,445

Collection

Kinase: IDG Consortium (Comple... 5 | 37
Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

enlarged heart 2 | 210
enlarged spleen 2 | 41
increased mean platelet volume 2 | 45
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal response to new envir... 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal spleen morphology 1 | 55
abnormal thymus morphology 1 | 7
anophthalmia 1 | 33
cataract 1 | 92
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
enlarged thymus 1 | 5
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased anti-nuclear antigen... 1 | 19
increased body length 1 | 32
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased glycosylated hemoglo... 1 | 1
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 19 | 11,493
ependymoma 12 | 4,679
medulloblastoma, large-cell 11 | 6,241
osteosarcoma 11 | 7,950
ovarian cancer 11 | 8,520
Kidney cancer 10 | 2,613
glioblastoma 10 | 5,792
adult high grade glioma 9 | 3,801
atypical teratoid / rhabdoid tumor 9 | 5,112
lung cancer 9 | 4,740
Breast cancer 8 | 3,578
malignant mesothelioma 8 | 3,232
psoriasis 8 | 6,694
interstitial cystitis 7 | 2,312
primitive neuroectodermal tumor 7 | 3,035
invasive ductal carcinoma 6 | 2,951
non-small cell lung cancer 6 | 2,890
Cancer 5 | 2,499
ductal carcinoma in situ 5 | 1,745
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
subependymal giant cell astrocytoma 5 | 2,287
breast carcinoma 4 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
nasopharyngeal carcinoma 4 | 1,058
pancreatic cancer 4 | 2,398
Astrocytoma, Pilocytic 3 | 3,081
Blastic phase chronic myeloid leukemia 3 | 58
Chronic Myelocytic Leukemia Accelerated Phase 3 | 59
Chronic phase chronic myeloid leukemia 3 | 45
Hamman-Rich syndrome 3 | 34
Multiple myeloma 3 | 1,332
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 3 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 3 | 47
Schizophrenia 3 | 1,160
Stomach Neoplasms 3 | 300
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
group 4 medulloblastoma 3 | 1,855
lung adenocarcinoma 3 | 2,716
medulloblastoma 3 | 720
oligodendroglioma 3 | 2,850
Arthritis 2 | 290
Atopic dermatitis 2 | 952
Autistic Disorder 2 | 364
Endometriosis 2 | 540
Glucose Intolerance 2 | 19
Impaired glucose tolerance 2 | 28
Insulin Resistance 2 | 72
Pick disease 2 | 1,894
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis 2 | 2,010
tuberculosis and treatment for 3 months 2 | 179
ulcerative colitis 2 | 1,819
Abdominal Pain 1 | 98
Abnormality of metabolism/homeostasis 1 | 134
Acquired metabolic disease 1 | 336
Acute myeloid leukemia, disease 1 | 30
Adenocarcinoma 1 | 122
Adenocarcinoma of lung 1 | 142
BILIARY TRACT ABNORMALITY 1 | 16
Biliary Tract Diseases 1 | 16
Breast Neoplasms 1 | 445
CMM1 1 | 5
Carcinoma, Squamous Cell 1 | 110
Cardiomegaly 1 | 116
Cardiomyopathies 1 | 110
Cardiovascular system disease 1 | 246
Early infantile epileptic encephalopathy with suppression bursts 1 | 10
Fibromyalgia 1 | 19
Gaucher disease type 1 1 | 180
Heroin dependence 1 | 30
Hyperpigmented macules 1 | 42
Hypertrophy, Left Ventricular 1 | 24
Juvenile polyposis syndrome 1 | 7
Left Ventricular Hypertrophy 1 | 47
Mammary Neoplasms 1 | 425
Nasal Polyps 1 | 10
Nijmegen breakage syndrome 1 | 24
Osteoporosis 1 | 363
Papillary adenocarcinoma 1 | 2
Papillary thyroid carcinoma 1 | 43
Premature ovarian failure 1 | 65
Rectal prolapse 1 | 19
Renal Cell Carcinoma 1 | 214
Retinitis pigmentosa 23 1 | 27
Salivary Gland Neoplasms 1 | 46
Seckel syndrome 1 | 34
Somatic mutation 1 | 61
Sporotrichosis 1 | 10
Squamous cell carcinoma 1 | 129
Vitiligo 1 | 73
West Syndrome 1 | 28
facioscapulohumeral dystrophy 1 | 288
sarcoidosis 1 | 370

Tissue

Blood and immune system 22 | 16,909
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Cardiovascular System 21 | 15,192

Target Family

Kinase 22 | 634

DTO Protein Class (3)

CAMKL family 22 | 22
STE20 family 31 | 31
CDK family 21 | 21
MAPK family 15 | 15
EPH family 14 | 14
C-C chemokine receptor 13 | 13
STKR family 12 | 12
NEK family 11 | 11
PI3-PI4 kinase family 11 | 11
SRC family 11 | 11
DYRK family 10 | 10
MLK family 10 | 10
P2Y receptor 10 | 10
PKC family 9 | 9
DMPK family 8 | 8
PIKK family 8 | 8
RSK family 8 | 8
STE11 family 8 | 8
CK1 family 7 | 7
CLK family 7 | 7
GRK family 7 | 7
RAF family 7 | 7
STE7 family 7 | 7
Alpha adrenoceptor 6 | 6
MAST family 6 | 6
RGC family 6 | 6
SCY1 family 6 | 6
TEC family 6 | 6
5-HT1 receptor 5 | 5
5-HT3 receptor sub-subfamily 5 | 5
ABC1 family 5 | 5
Alpha family 5 | 5
CAMK1 family 5 | 5
CDKL family 5 | 5
DAPK family 5 | 5
MAPKAPK family 5 | 5
MLCK family 5 | 5
PDGFR family 5 | 5
PDHK family 5 | 5
PKA family 5 | 5
PLK family 5 | 5
RIPK family 5 | 5
TSSK family 5 | 5
ULK family 5 | 5
Adenylate kinase family 4 | 4
C-X-C chemokine receptor 4 | 4
CAMK2 family 4 | 4
CK2 family 4 | 4
EGFR family 4 | 4
FGFR family 4 | 4
Hexokinase family 4 | 4
IKK family 4 | 4
IRAK family 4 | 4
JAKA family 4 | 4
LISK family 4 | 4
NAK family 4 | 4
NDR family 4 | 4
PEK family 4 | 4
PIM family 4 | 4
TRIO family 4 | 4
WNK family 4 | 4
5-HT2 receptor 3 | 3
AKT family 3 | 3
AUR family 3 | 3
AXL family 3 | 3
Beta adrenoceptor 3 | 3
DCAMKL family 3 | 3
DCK-DGK family 3 | 3
Diacylglycerol kinase family 3 | 3
INSR family 3 | 3
Inositol phosphokinase (IPK) f... 3 | 3
LMR family 3 | 3
MET family 3 | 3
NKF1 family 3 | 3
Other-UNIQUE family 3 | 3
PKD family 3 | 3
PKN family 3 | 3
RCK family 3 | 3
RIO family 3 | 3
SGK family 3 | 3
SRPK family 3 | 3
TRBL family 3 | 3
TRK family 3 | 3
Type II pantothenate kinase fa... 3 | 3
VEGFR family 3 | 3
VRK family 3 | 3
WEE family 3 | 3
YANK family 3 | 3
ABL family 2 | 2
ACK family 2 | 2
Alpha-7-CHRNA7 sub-subfamily 2 | 2
BUB family 2 | 2
CAMK-UNIQUE family 2 | 2
CSK family 2 | 2
FGGY kinase family 2 | 2
NRBP family 2 | 2
STE-UNIQUE family 2 | 2
TIE family 2 | 2
TRPM2 sub-subfamily 2 | 2
TTBK family 2 | 2

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
PAS domain-containing serine/threonine-protein kinase PASK Tbio Kinase -1.01354 12.3 95
Serine/threonine-protein kinase MARK2 MARK2 Tchem Kinase -2.49873 272.3 322
Serine/threonine-protein kinase SIK3 SIK3 Tchem Kinase -1.18286 18.2 0
Serine/threonine-protein kinase BRSK2 BRSK2 Tchem Kinase -1.92813 85.3 187
Serine/threonine-protein kinase SIK2 SIK2 Tchem Kinase -1.50719 36.5 233
Serine/threonine-protein kinase NIM1 NIM1K Tchem Kinase -1.32387 20.9 101
Hormonally up-regulated neu tumor-associated kinase HUNK Tchem Kinase -1.30024 24.4 273
Serine/threonine-protein kinase BRSK1 BRSK1 Tchem Kinase -1.44039 28.9 301
Serine/threonine-protein kinase Chk1 CHEK1 Tchem Kinase -3.04423 1089.6 1375
Serine/threonine-protein kinase MARK1 MARK1 Tchem Kinase -1.77236 56.1 318