Development Level

Tchem 44 | 1,598
Tclin 36 | 613
Tbio 13 | 11,445

Collection

Kinase: IDG Consortium (Target... 2 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal seminal vesicle morph... 4 | 114
preweaning lethality, incomple... 4 | 499
embryonic lethality prior to t... 3 | 278
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal pericardium morpholog... 2 | 26
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
increased monocyte cell number 2 | 63
abnormal bone mineralization 1 | 38
abnormal epididymis morphology 1 | 42
abnormal eye anterior chamber ... 1 | 9
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal maxilla morphology 1 | 17
abnormal response to new envir... 1 | 10
abnormal rib morphology 1 | 10
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal urinary bladder morph... 1 | 11
abnormal vocalization 1 | 21
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged heart 1 | 210
impaired righting response 1 | 26
increased B cell number 1 | 9
increased CD4-positive, alpha ... 1 | 4
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 87 | 11,493
Cancer 69 | 2,499
osteosarcoma 59 | 7,950
ovarian cancer 51 | 8,520
medulloblastoma, large-cell 48 | 6,241
Kidney cancer 46 | 2,613
glioblastoma 45 | 5,792
lung cancer 43 | 4,740
psoriasis 43 | 6,694
Breast cancer 39 | 3,578
non-small cell lung cancer 39 | 2,890
atypical teratoid / rhabdoid tumor 38 | 5,112
Blastic phase chronic myeloid leukemia 34 | 58
Chronic Myelocytic Leukemia Accelerated Phase 34 | 59
Chronic phase chronic myeloid leukemia 32 | 45
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 32 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 32 | 47
ependymoma 32 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 32 | 3,291
group 3 medulloblastoma 30 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
lung carcinoma 29 | 2,843
invasive ductal carcinoma 28 | 2,951
malignant mesothelioma 28 | 3,232
interstitial cystitis 27 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
lung adenocarcinoma 26 | 2,716
Astrocytoma, Pilocytic 25 | 3,081
oligodendroglioma 25 | 2,850
pancreatic cancer 25 | 2,398
astrocytic glioma 24 | 2,597
ulcerative colitis 24 | 1,819
Renal Cell Carcinoma 22 | 214
adult high grade glioma 22 | 3,801
pituitary cancer 22 | 1,972
Autosomal recessive predisposition 19 | 1,442
primitive neuroectodermal tumor 19 | 3,035
subependymal giant cell astrocytoma 18 | 2,287
Skin cancer 17 | 469
cystic fibrosis 17 | 1,696
tuberculosis 17 | 2,010
Melanoma 16 | 711
breast carcinoma 16 | 1,638
cutaneous lupus erythematosus 16 | 1,057
ductal carcinoma in situ 16 | 1,745
Breast Neoplasms 15 | 445
Gastrointestinal stromal tumor 15 | 62
Hamman-Rich syndrome 14 | 34
Mammary Neoplasms 14 | 425
colon cancer 14 | 1,478
group 4 medulloblastoma 14 | 1,855
spina bifida 14 | 1,074
Liver cancer 13 | 604
Schizophrenia 13 | 1,160
adrenocortical carcinoma 13 | 1,428
astrocytoma 12 | 1,146
diabetes mellitus 12 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
primary pancreatic ductal adenocarcinoma 12 | 1,109
Pancreatic Neuroendocrine Tumor 11 | 45
Pick disease 11 | 1,894
Sarcoma of soft tissue 11 | 11
Bipolar Disorder 10 | 666
Carcinoma of thyroid 10 | 17
Immune system cancer 10 | 140
Papillary thyroid carcinoma 10 | 43
pediatric high grade glioma 10 | 1,064
Alzheimer's disease 9 | 658
Atopic dermatitis 9 | 952
Diarrhea 9 | 253
Down syndrome 9 | 499
Liver cell carcinoma 9 | 15
Lymphoid leukemia 9 | 160
Neoplasm Metastasis 9 | 168
Stomach Neoplasms 9 | 300
esophageal adenocarcinoma 9 | 737
primary Sjogren syndrome 9 | 735
Cognitive delay 8 | 608
Depressive disorder 8 | 409
Dull intelligence 8 | 645
Exophthalmos 8 | 112
Global developmental delay 8 | 608
Intellectual disability 8 | 1,016
Liver Cirrhosis, Experimental 8 | 769
Low intelligence 8 | 645
Lung Neoplasms 8 | 232
Mental Retardation 8 | 645
Mental and motor retardation 8 | 608
Mental deficiency 8 | 645
Obesity 8 | 678
Orbital separation excessive 8 | 244
Poor school performance 8 | 645
Prominent eyes 8 | 96
Prominent globes 8 | 96
Protruding eyes 8 | 96
Rheumatoid arthritis 8 | 1,191
non-small cell lung carcinoma 8 | 317
Chronic Lymphocytic Leukemia 7 | 262
Prostatic Neoplasms 7 | 495
gastric carcinoma 7 | 807

Tissue

Digestive Tract 93 | 17,369
Endocrine System 93 | 18,159
Skin and soft tissues 93 | 17,230
Female tissues 92 | 17,400
Male tissues 92 | 17,142
Blood and immune system 91 | 16,909
Urinary Tract 91 | 16,678
Liver and Pancreas 90 | 16,750
Respiratory system 90 | 16,393
Nervous System 89 | 16,725
Cardiovascular System 86 | 15,192

Target Family

Kinase 91 | 634
Enzyme 2 | 4,145

DTO Protein Class (2)

TK group 93 | 93
Olfactory receptor 421 | 421
Other group 87 | 87
CAMK group 77 | 77
CMGC group 70 | 70
AGC group 65 | 65
STE group 48 | 48
TKL group 45 | 45
Lipid kinase 30 | 30
Atypical group 28 | 28
Chemokine receptor 24 | 24
Taste 2 receptor 24 | 24
Gamma-aminobutyric acid recept... 19 | 19
Purinoceptor 18 | 18
Acetylcholine receptor subfami... 17 | 17
Other small molecule kinase 15 | 15
5-hydroxytryptamine receptor 12 | 12
CK1 group 12 | 12
Frizzled receptor 10 | 10
Mas proto-oncogene and Mas-rel... 10 | 10
Adrenoceptor 9 | 9
Carbohydrate kinase 9 | 9
A (Shaker) subfamily 8 | 8
Calcium-activated subfamily 8 | 8
H (Eag) subfamily 8 | 8
LTrpC subfamily 8 | 8
Metabotropic glutamate recepto... 8 | 8
Histamine receptor 7 | 7
Nucleoside kinase 7 | 7
Dopamine receptor 6 | 6
Glucagon receptor 6 | 6
Lysophospholipid (LPA) recepto... 6 | 6
Melanin-concentrating hormone ... 6 | 6
Nucleotide kinase 6 | 6
RGC group 6 | 6
STrpC subfamily 6 | 6
TrpV subfamily 6 | 6
Vomeronasal receptor 6 | 6
5-hydroxytryptamine receptor s... 5 | 5
Acetylcholine receptor (muscar... 5 | 5
Adenosine receptor 5 | 5
Glycine receptor subfamily 5 | 5
KQT subfamily 5 | 5
Leukotriene receptor 5 | 5
Melanocortin receptor 5 | 5
Neuropeptide Y receptor 5 | 5
Angiotensin receptor 4 | 4
C (Shaw) subfamily 4 | 4
Cannabinoid receptor 4 | 4
Free fatty acid receptor 4 | 4
G subfamily 4 | 4
GABA-B receptor 4 | 4
KCNE subfamily 4 | 4
Latrophilin receptor 4 | 4
Proteinase-activated receptor 4 | 4
Anaphylatoxin receptor 3 | 3
Bombesin receptor 3 | 3
Cadherin EGF LAG (CELSR) recep... 3 | 3
D (Shal) subfamily 3 | 3
Endothelin receptor 3 | 3
Formyl peptide receptor 3 | 3
Galanin receptor 3 | 3
Hydroxycarboxylic acid recepto... 3 | 3
Polycystin subfamily 3 | 3
S subfamily 3 | 3
Tachykinin receptor 3 | 3
Taste 1 receptor 3 | 3
B (Shab) subfamily 2 | 2
Bradykinin receptor 2 | 2
CACNA1I subfamily 2 | 2
Calcitonin receptor 2 | 2
Calcium-sensing receptor 2 | 2
Cholecystokinin receptor 2 | 2
Corticotropin-releasing factor... 2 | 2
Glycoprotein hormone receptor 2 | 2
Gonadotrophin-releasing hormon... 2 | 2
KCNJ12 subfamily 2 | 2
Melatonin receptor 2 | 2
NR1-GRIN1 subfamily 2 | 2
Neuromedin U receptor 2 | 2
Neuropeptide FF-neuropeptide A... 2 | 2
Neuropeptide W-neuropeptide B ... 2 | 2
Neurotensin receptor 2 | 2
Parathyroid hormone receptor 2 | 2
Phosphorylase b kinase regulat... 2 | 2
Two pore calcium channel subfa... 2 | 2
V subfamily 2 | 2
CFTR transporter subfamily 1 | 1
CLCNKB subfamily 1 | 1
ClC-2-CLCN2 subfamily 1 | 1
ClC-3-CLCN3 subfamily 1 | 1
ClC-4-CLCN4 subfamily 1 | 1
ClC-5-CLCN5 subfamily 1 | 1
ClC-6-CLCN6 subfamily 1 | 1
ClC-7-CLCN7 subfamily 1 | 1
GRID2 subfamily 1 | 1
SCN4B family 1 | 1
SCNN1B subfamily 1 | 1
SCNN1D subfamily 1 | 1
SCNN1G subfamily 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Abelson tyrosine-protein kinase 2 ABL2 Tchem Kinase -1.86293 71.2 358
Tyrosine-protein kinase FRK FRK Tchem Kinase -1.68365 49.2 394
Megakaryocyte-associated tyrosine-protein kinase MATK Tbio Kinase -2.98596 792.3 265
Tyrosine-protein kinase TXK TXK Tchem Kinase -2.28365 191.1 194
Ephrin type-B receptor 3 EPHB3 Tchem Kinase -1.68968 47.7 409
Ephrin type-A receptor 5 EPHA5 Tchem Kinase -2.28294 191.7 407
Ephrin type-B receptor 4 EPHB4 Tchem Kinase -2.26622 206.3 514
Ephrin type-B receptor 1 EPHB1 Tchem Kinase -1.70013 52.0 389