Development Level

Tclin 1 | 613

Disease

Abnormal cortical bone morphology 1 | 22
Abnormality of epiphysis morphology 1 | 39
Abnormality of metabolism/homeostasis 1 | 134
Abnormality of the ankles 1 | 5
Abnormality of the hip bone 1 | 16
Abnormality of the knee 1 | 6
Abnormality of the musculature 1 | 16
Absence Epilepsy 1 | 22
Acral ulceration leading to autoamputation of digits 1 | 3
Acro-Osteolysis 1 | 12
Administration of Local Anesthetic Nerve Block 1 | 14
Administration of Regional Anesthesia 1 | 7
Anhidrosis 1 | 23
Anosmia 1 | 22
Autonomic nervous system disorders 1 | 19
Bipolar disorder in remission 1 | 19
Blurred vision 1 | 19
Bradycardia 1 | 36
Burning mouth syndrome 1 | 7
Chronic pain 1 | 9
DOID:2627 1 | 94
Decreased bone mineral density Z score 1 | 31
Decreased nerve conduction velocity 1 | 35
Decreased pain sensation 1 | 17
Decreased sensory nerve conduction velocities (NCV) 1 | 8
Dental caries 1 | 164
Dysautonomia 1 | 20
Dystrophic fingernails 1 | 18
Dystrophic toenail changes 1 | 12
Elevated heart rate 1 | 25
Epilepsies, Myoclonic 1 | 32
Epileptic Encephalopathy, Early Infantile, 6 1 | 8
Epileptic drop attack 1 | 11
Erythema 1 | 58
Erythermalgia, Primary 1 | 1
Eye pain 1 | 2
Febrile Convulsions 1 | 14
Flushing 1 | 60
Focal Clonic Seizures 1 | 9
Foot acroosteolysis 1 | 5
GENERALIZED EPILEPSY WITH FEBRILE SEIZURES PLUS, TYPE 1 1 | 7
GENERALIZED EPILEPSY WITH FEBRILE SEIZURES PLUS, TYPE 2 1 | 2
Generalized Epilepsy With Febrile Seizures Plus, 7 1 | 1
Generalized epilepsy with febrile seizures plus 1 | 7
Generalized epilepsy with febrile seizures plus, type 7 1 | 1
Generalized myoclonic seizures 1 | 30
Glossopharyngeal neuralgia 1 | 5
Hemorrhoids 1 | 13
Hereditary Motor and Sensory-Neuropathy Type II 1 | 4
Hereditary sensory and autonomic neuropathy type 2 1 | 4
Hereditary sensory neuropathy 1 | 11
Herpesviridae Infections 1 | 3
Hyperekplexia 1 | 16
Hyperhidrosis disorder 1 | 81
Hyperhidrosis, episodic 1 | 4
Hypogeusia 1 | 5
Hypohidrosis 1 | 34
Hypotonic seizures 1 | 11
Increased sweating 1 | 81
Indifference to Pain, Congenital, Autosomal Recessive 1 | 1
Infantile Severe Myoclonic Epilepsy 1 | 8
Jaw pain 1 | 2
Lacrimation abnormality 1 | 4
Local Anesthesia for Endotracheal Intubation 1 | 6
Local anesthesia, by infiltration 1 | 14
Lordosis 1 | 54
Mixed Epilepsy 1 | 3
Mouth Irritation 1 | 12
Myalgia 1 | 54
Myoclonic Epilepsies, Progressive 1 | 44
NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IIA 1 | 4
Neonatal onset 1 | 21
Neuralgia, Postherpetic 1 | 3
Neuropathy, Hereditary Sensory and Autonomic, Type 2A 1 | 4
Obtundation status 1 | 7
Pain 1 | 103
Palpitations 1 | 18
Paronychia Inflammation 1 | 9
Partial Epilepsy Treatment Adjunct 1 | 16
Pediculosis capitis 1 | 7
Peripheral Neuropathy 1 | 134
Photosensitivity of skin 1 | 51
Prevention of Seizures following Cranial Trauma or Surgery 1 | 7
Pruritus 1 | 58
Regional Anesthesia for Ophthalmologic Surgery 1 | 6
Seizures in Neurosurgery 1 | 7
Seizures, Focal 1 | 14
Sense of smell impaired 1 | 21
Sweating 1 | 81
Tapering fingers (finding) 1 | 25
Tinea Infections 1 | 10
Tinea corporis 1 | 25
Tonic - clonic seizures 1 | 44
Tremor 1 | 113
Trigeminal Neuralgia 1 | 24
Urethritis 1 | 10
Urinary Incontinence 1 | 50
Urinary Tract Irritation 1 | 24
Xerostomia 1 | 42
multidrug-resistant tuberculosis 1 | 7

Tissue

Blood and immune system 1 | 16,909
Cardiovascular System 1 | 15,192
Digestive Tract 1 | 17,369
Endocrine System 1 | 18,159
Female tissues 1 | 17,400
Liver and Pancreas 1 | 16,750
Male tissues 1 | 17,142
Nervous System 1 | 16,725
Respiratory system 1 | 16,393
Skin and soft tissues 1 | 17,230
Urinary Tract 1 | 16,678

Target Family

Ion Channel 1 | 344

DTO Protein Class (2)

Nav1.7-SCN9A subfamily 1 | 1
Olfactory receptor 421 | 421
TK group 93 | 93
Other group 87 | 87
CAMK group 77 | 77
CMGC group 70 | 70
AGC group 65 | 65
STE group 48 | 48
TKL group 45 | 45
Lipid kinase 30 | 30
Atypical group 28 | 28
Chemokine receptor 24 | 24
Taste 2 receptor 24 | 24
Gamma-aminobutyric acid recept... 19 | 19
Purinoceptor 18 | 18
Acetylcholine receptor subfami... 17 | 17
Other small molecule kinase 15 | 15
5-hydroxytryptamine receptor 12 | 12
CK1 group 12 | 12
Frizzled receptor 10 | 10
Mas proto-oncogene and Mas-rel... 10 | 10
Adrenoceptor 9 | 9
Carbohydrate kinase 9 | 9
A (Shaker) subfamily 8 | 8
Calcium-activated subfamily 8 | 8
H (Eag) subfamily 8 | 8
LTrpC subfamily 8 | 8
Metabotropic glutamate recepto... 8 | 8
Histamine receptor 7 | 7
Nucleoside kinase 7 | 7
Dopamine receptor 6 | 6
Glucagon receptor 6 | 6
Lysophospholipid (LPA) recepto... 6 | 6
Melanin-concentrating hormone ... 6 | 6
Nucleotide kinase 6 | 6
RGC group 6 | 6
STrpC subfamily 6 | 6
TrpV subfamily 6 | 6
Vomeronasal receptor 6 | 6
5-hydroxytryptamine receptor s... 5 | 5
Acetylcholine receptor (muscar... 5 | 5
Adenosine receptor 5 | 5
Glycine receptor subfamily 5 | 5
KQT subfamily 5 | 5
Leukotriene receptor 5 | 5
Melanocortin receptor 5 | 5
Neuropeptide Y receptor 5 | 5
Angiotensin receptor 4 | 4
C (Shaw) subfamily 4 | 4
Cannabinoid receptor 4 | 4
Free fatty acid receptor 4 | 4
G subfamily 4 | 4
GABA-B receptor 4 | 4
KCNE subfamily 4 | 4
Latrophilin receptor 4 | 4
Proteinase-activated receptor 4 | 4
Anaphylatoxin receptor 3 | 3
Bombesin receptor 3 | 3
Cadherin EGF LAG (CELSR) recep... 3 | 3
D (Shal) subfamily 3 | 3
Endothelin receptor 3 | 3
Formyl peptide receptor 3 | 3
Galanin receptor 3 | 3
Hydroxycarboxylic acid recepto... 3 | 3
Polycystin subfamily 3 | 3
S subfamily 3 | 3
Tachykinin receptor 3 | 3
Taste 1 receptor 3 | 3
B (Shab) subfamily 2 | 2
Bradykinin receptor 2 | 2
CACNA1I subfamily 2 | 2
Calcitonin receptor 2 | 2
Calcium-sensing receptor 2 | 2
Cholecystokinin receptor 2 | 2
Corticotropin-releasing factor... 2 | 2
Glycoprotein hormone receptor 2 | 2
Gonadotrophin-releasing hormon... 2 | 2
KCNJ12 subfamily 2 | 2
Melatonin receptor 2 | 2
NR1-GRIN1 subfamily 2 | 2
Neuromedin U receptor 2 | 2
Neuropeptide FF-neuropeptide A... 2 | 2
Neuropeptide W-neuropeptide B ... 2 | 2
Neurotensin receptor 2 | 2
Parathyroid hormone receptor 2 | 2
Phosphorylase b kinase regulat... 2 | 2
Two pore calcium channel subfa... 2 | 2
V subfamily 2 | 2
CFTR transporter subfamily 1 | 1
CLCNKB subfamily 1 | 1
ClC-2-CLCN2 subfamily 1 | 1
ClC-3-CLCN3 subfamily 1 | 1
ClC-4-CLCN4 subfamily 1 | 1
ClC-5-CLCN5 subfamily 1 | 1
ClC-6-CLCN6 subfamily 1 | 1
ClC-7-CLCN7 subfamily 1 | 1
GRID2 subfamily 1 | 1
SCN4B family 1 | 1
SCNN1B subfamily 1 | 1
SCNN1D subfamily 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium channel protein type 9 subunit alpha SCN9A Tclin Ion Channel -2.57994 379.2 327