Development Level

Tchem 18 | 1,598
Tbio 10 | 11,445
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 6 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

abnormal embryo size 2 | 220
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
persistence of hyaloid vascula... 2 | 33
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating creatini... 1 | 39
decreased grip strength 1 | 116
edema 1 | 59
enlarged lymph nodes 1 | 37
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92

Disease

Carcinoma 23 | 11,493
osteosarcoma 20 | 7,950
glioblastoma 18 | 5,792
medulloblastoma, large-cell 18 | 6,241
ovarian cancer 18 | 8,520
atypical teratoid / rhabdoid tumor 13 | 5,112
ependymoma 13 | 4,679
adult high grade glioma 12 | 3,801
psoriasis 11 | 6,694
Kidney cancer 10 | 2,613
lung cancer 10 | 4,740
Schizophrenia 9 | 1,160
primitive neuroectodermal tumor 9 | 3,035
Cancer 8 | 2,499
ulcerative colitis 8 | 1,819
Breast cancer 7 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
group 3 medulloblastoma 6 | 4,104
lung carcinoma 6 | 2,843
non-small cell lung cancer 6 | 2,890
oligodendroglioma 6 | 2,850
Astrocytoma, Pilocytic 5 | 3,081
astrocytic glioma 5 | 2,597
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
invasive ductal carcinoma 5 | 2,951
juvenile dermatomyositis 5 | 1,187
malignant mesothelioma 5 | 3,232
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
Bipolar Disorder 4 | 666
DOID:2627 4 | 94
Diffuse large B-cell lymphoma 4 | 39
Lymphoma, Large B-Cell, Diffuse 4 | 34
Pick disease 4 | 1,894
Waldenstrons macroglobulinemia 4 | 765
follicular lymphoma 4 | 20
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung adenocarcinoma 4 | 2,716
medulloblastoma 4 | 720
primary Sjogren syndrome 4 | 735
primary pancreatic ductal adenocarcinoma 4 | 1,109
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Autosomal recessive predisposition 3 | 1,442
Endometrial cancer 3 | 311
Hypoplastic mandible condyle 3 | 275
Liver cancer 3 | 604
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Rheumatoid arthritis 3 | 1,191
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
ACTIVATED PI3K-DELTA SYNDROME 2 | 2
Arthrogryposis 2 | 54
Cataract 2 | 297
Centronuclear myopathy 2 | 27
Decreased antibody level in blood 2 | 35
Diarrhea 2 | 253
Failure to gain weight 2 | 365
Fatigue 2 | 182
Fibrosis 2 | 44
Frontal bossing 2 | 157
Hypogammaglobulinemia 2 | 35
Hypothyroidism 2 | 122
Immunologic Deficiency Syndromes 2 | 113
Joint laxity 2 | 54
Large intestine cancer 2 | 126
Lens Opacities 2 | 231
Leukemia 2 | 104
Myopia 2 | 176
Neoplasm Metastasis 2 | 168
Parkinson's disease 2 | 392
Pediatric failure to thrive 2 | 365
Prostatic Neoplasms 2 | 495
Splenomegaly 2 | 190
Upper respiratory tract disease 2 | 15
Vascular disease 2 | 319
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
atypical teratoid/rhabdoid tumor 2 | 357
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
periodontitis 2 | 293
posterior fossa group B ependymoma 2 | 416
progressive supranuclear palsy 2 | 676
sonic hedgehog group medulloblastoma 2 | 467
Neuroleptic malignant syndrome 1 | 9
Paranasal Sinus Diseases 1 | 34
Recurrent skin infections 1 | 21
Thin hypoplastic alae nasi 1 | 51

Tissue

Blood and immune system 30 | 16,909
Digestive Tract 30 | 17,369
Endocrine System 30 | 18,159
Female tissues 30 | 17,400
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Nervous System 30 | 16,725
Respiratory system 30 | 16,393
Skin and soft tissues 30 | 17,230
Cardiovascular System 29 | 15,192
Urinary Tract 29 | 16,678

Target Family

Kinase 29 | 634
Non-IDG 1 | 12,091

DTO Protein Class (2)

Lipid kinase 30 | 30
Olfactory receptor 421 | 421
TK group 93 | 93
Other group 87 | 87
CAMK group 77 | 77
CMGC group 70 | 70
AGC group 65 | 65
STE group 48 | 48
TKL group 45 | 45
Atypical group 28 | 28
Chemokine receptor 24 | 24
Taste 2 receptor 24 | 24
Gamma-aminobutyric acid recept... 19 | 19
Purinoceptor 18 | 18
Acetylcholine receptor subfami... 17 | 17
Other small molecule kinase 15 | 15
5-hydroxytryptamine receptor 12 | 12
CK1 group 12 | 12
Frizzled receptor 10 | 10
Mas proto-oncogene and Mas-rel... 10 | 10
Adrenoceptor 9 | 9
Carbohydrate kinase 9 | 9
A (Shaker) subfamily 8 | 8
Calcium-activated subfamily 8 | 8
H (Eag) subfamily 8 | 8
LTrpC subfamily 8 | 8
Metabotropic glutamate recepto... 8 | 8
Histamine receptor 7 | 7
Nucleoside kinase 7 | 7
Dopamine receptor 6 | 6
Glucagon receptor 6 | 6
Lysophospholipid (LPA) recepto... 6 | 6
Melanin-concentrating hormone ... 6 | 6
Nucleotide kinase 6 | 6
RGC group 6 | 6
STrpC subfamily 6 | 6
TrpV subfamily 6 | 6
Vomeronasal receptor 6 | 6
5-hydroxytryptamine receptor s... 5 | 5
Acetylcholine receptor (muscar... 5 | 5
Adenosine receptor 5 | 5
Glycine receptor subfamily 5 | 5
KQT subfamily 5 | 5
Leukotriene receptor 5 | 5
Melanocortin receptor 5 | 5
Neuropeptide Y receptor 5 | 5
Angiotensin receptor 4 | 4
C (Shaw) subfamily 4 | 4
Cannabinoid receptor 4 | 4
Free fatty acid receptor 4 | 4
G subfamily 4 | 4
GABA-B receptor 4 | 4
KCNE subfamily 4 | 4
Latrophilin receptor 4 | 4
Proteinase-activated receptor 4 | 4
Anaphylatoxin receptor 3 | 3
Bombesin receptor 3 | 3
Cadherin EGF LAG (CELSR) recep... 3 | 3
D (Shal) subfamily 3 | 3
Endothelin receptor 3 | 3
Formyl peptide receptor 3 | 3
Galanin receptor 3 | 3
Hydroxycarboxylic acid recepto... 3 | 3
Polycystin subfamily 3 | 3
S subfamily 3 | 3
Tachykinin receptor 3 | 3
Taste 1 receptor 3 | 3
B (Shab) subfamily 2 | 2
Bradykinin receptor 2 | 2
CACNA1I subfamily 2 | 2
Calcitonin receptor 2 | 2
Calcium-sensing receptor 2 | 2
Cholecystokinin receptor 2 | 2
Corticotropin-releasing factor... 2 | 2
Glycoprotein hormone receptor 2 | 2
Gonadotrophin-releasing hormon... 2 | 2
KCNJ12 subfamily 2 | 2
Melatonin receptor 2 | 2
NR1-GRIN1 subfamily 2 | 2
Neuromedin U receptor 2 | 2
Neuropeptide FF-neuropeptide A... 2 | 2
Neuropeptide W-neuropeptide B ... 2 | 2
Neurotensin receptor 2 | 2
Parathyroid hormone receptor 2 | 2
Phosphorylase b kinase regulat... 2 | 2
Two pore calcium channel subfa... 2 | 2
V subfamily 2 | 2
CFTR transporter subfamily 1 | 1
CLCNKB subfamily 1 | 1
ClC-2-CLCN2 subfamily 1 | 1
ClC-3-CLCN3 subfamily 1 | 1
ClC-4-CLCN4 subfamily 1 | 1
ClC-5-CLCN5 subfamily 1 | 1
ClC-6-CLCN6 subfamily 1 | 1
ClC-7-CLCN7 subfamily 1 | 1
GRID2 subfamily 1 | 1
SCN4B family 1 | 1
SCNN1B subfamily 1 | 1
SCNN1D subfamily 1 | 1
SCNN1G subfamily 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Diacylglycerol kinase eta DGKH Tbio Kinase -1.45863 29.5 92
Calsyntenin-1 CLSTN1 Tbio Non-IDG -1.09760 15.0 131
Inositol polyphosphate multikinase IPMK Tbio Kinase -1.55144 39.0 159
Inositol-trisphosphate 3-kinase B ITPKB Tchem Kinase -1.44569 29.5 168
Diacylglycerol kinase theta DGKQ Tbio Kinase -1.58632 35.6 169
Inositol-trisphosphate 3-kinase A ITPKA Tchem Kinase -1.42824 28.0 156
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta PIK3C2B Tchem Kinase -1.50611 34.7 157
Phosphatidylinositol 4-kinase beta PI4KB Tchem Kinase -1.85524 71.3 104
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma PIK3C2G Tchem Kinase -0.96984 8.60 87
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha PIK3C2A Tchem Kinase -3.50398 3129.0 525