Development Level

Tchem 6 | 1,598
Tbio 1 | 11,445
Tclin 1 | 613

IMPC Phenotype

increased aggression 1 | 4
limb grasping 1 | 41

Disease

Carcinoma 7 | 11,493
Kidney cancer 5 | 2,613
Melanoma 4 | 711
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
medulloblastoma, large-cell 4 | 6,241
subependymal giant cell astrocytoma 3 | 2,287
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Dementia 2 | 175
Schizophrenia 2 | 1,160
adult high grade glioma 2 | 3,801
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
ovarian cancer 2 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
ulcerative colitis 2 | 1,819
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Acute kidney injury 1 | 70
Adverse reaction to drug 1 | 61
Alzheimer Disease 1 | 83
Amyloidosis 1 | 67
Amyotrophic Lateral Sclerosis, Guam Form 1 | 2
Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex 1 1 | 2
Amyotrophic lateral sclerosis 1 | 451
Atrophic 1 | 10
Atrophy 1 | 10
Bradycardia 1 | 36
Brugada Syndrome (disorder) 1 | 15
Brugada syndrome 1 | 29
Cardiac Arrhythmia 1 | 103
Cardiac conduction abnormalities 1 | 78
Chemical and Drug Induced Liver Injury 1 | 195
Chromosome 15q13.3 microdeletion syndrome 1 | 11
Colonic Polyps 1 | 3
Colorectal Neoplasms 1 | 243
Common Migraine 1 | 7
Conduction disorder of the heart 1 | 79
Congenital stationary night blindness 1 | 29
Degenerative polyarthritis 1 | 115
Dentin sensitivity 1 | 14
Difficulties with night vision 1 | 87
Disturbance in mood 1 | 3
Drug-Related Side Effects and Adverse Reactions 1 | 62
Dry skin 1 | 75
EKG abnormalities 1 | 78
Eczema 1 | 45
Electrocardiogram abnormal 1 | 81
Electrocardiogram change 1 | 78
Fascioliasis 1 | 17
Fuchs' endothelial dystrophy 1 | 24
Gaucher disease type 3 1 | 67
Heart conduction disease 1 | 83
Hypoplasia of optic disc 1 | 12
Iris disease 1 | 10
Itching of skin 1 | 18
Kidney Calculi 1 | 7
Kidney Diseases 1 | 114
Limb ischemia 1 | 15
Liver Cirrhosis 1 | 181
Liver cancer 1 | 604
Local anesthesia 1 | 40
Lupus Erythematosus, Systemic 1 | 67
Migraine Disorders 1 | 76
Migraine without Aura 1 | 11
Minor Skin Wound Pain 1 | 12
Mouth Irritation 1 | 12
Myopia 1 | 176
Neurodegenerative disease 1 | 414
Neuropathy 1 | 261
Night Blindness 1 | 101
Night blindness, congenital stationary 1 | 16
Nonorganic psychosis 1 | 84
Ophthalmomyiasis 1 | 3
Osteoarthritis 1 | 184
Pain 1 | 103
Pain agnosia 1 | 104
Panic disorder 1 | 61
Paralysed 1 | 42
Paralysis 1 | 9
Pityriasis versicolor 1 | 19
Prolonged QT interval 1 | 15
Reduced visual acuity 1 | 63
Right bundle branch block 1 | 17
Scotoma 1 | 22
Seborrheic dermatitis 1 | 31
Skin cancer 1 | 469
Skin irritation 1 | 12
Suppression of the Gag Reflex 1 | 12
Syncope 1 | 22
Ureteral obstruction 1 | 33
Xerosis 1 | 75
chronic kidney disease 1 | 90

Tissue

Endocrine System 8 | 18,159
Digestive Tract 7 | 17,369
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Blood and immune system 6 | 16,909
Female tissues 6 | 17,400
Nervous System 6 | 16,725
Cardiovascular System 5 | 15,192
Respiratory system 5 | 16,393

Target Family

Ion Channel 7 | 344
Non-IDG 1 | 12,091

DTO Protein Class (2)

LTrpC subfamily 8 | 8
Olfactory receptor 421 | 421
TK group 93 | 93
Other group 87 | 87
CAMK group 77 | 77
CMGC group 70 | 70
AGC group 65 | 65
STE group 48 | 48
TKL group 45 | 45
Lipid kinase 30 | 30
Atypical group 28 | 28
Chemokine receptor 24 | 24
Taste 2 receptor 24 | 24
Gamma-aminobutyric acid recept... 19 | 19
Purinoceptor 18 | 18
Acetylcholine receptor subfami... 17 | 17
Other small molecule kinase 15 | 15
5-hydroxytryptamine receptor 12 | 12
CK1 group 12 | 12
Frizzled receptor 10 | 10
Mas proto-oncogene and Mas-rel... 10 | 10
Adrenoceptor 9 | 9
Carbohydrate kinase 9 | 9
A (Shaker) subfamily 8 | 8
Calcium-activated subfamily 8 | 8
H (Eag) subfamily 8 | 8
Metabotropic glutamate recepto... 8 | 8
Histamine receptor 7 | 7
Nucleoside kinase 7 | 7
Dopamine receptor 6 | 6
Glucagon receptor 6 | 6
Lysophospholipid (LPA) recepto... 6 | 6
Melanin-concentrating hormone ... 6 | 6
Nucleotide kinase 6 | 6
RGC group 6 | 6
STrpC subfamily 6 | 6
TrpV subfamily 6 | 6
Vomeronasal receptor 6 | 6
5-hydroxytryptamine receptor s... 5 | 5
Acetylcholine receptor (muscar... 5 | 5
Adenosine receptor 5 | 5
Glycine receptor subfamily 5 | 5
KQT subfamily 5 | 5
Leukotriene receptor 5 | 5
Melanocortin receptor 5 | 5
Neuropeptide Y receptor 5 | 5
Angiotensin receptor 4 | 4
C (Shaw) subfamily 4 | 4
Cannabinoid receptor 4 | 4
Free fatty acid receptor 4 | 4
G subfamily 4 | 4
GABA-B receptor 4 | 4
KCNE subfamily 4 | 4
Latrophilin receptor 4 | 4
Proteinase-activated receptor 4 | 4
Anaphylatoxin receptor 3 | 3
Bombesin receptor 3 | 3
Cadherin EGF LAG (CELSR) recep... 3 | 3
D (Shal) subfamily 3 | 3
Endothelin receptor 3 | 3
Formyl peptide receptor 3 | 3
Galanin receptor 3 | 3
Hydroxycarboxylic acid recepto... 3 | 3
Polycystin subfamily 3 | 3
S subfamily 3 | 3
Tachykinin receptor 3 | 3
Taste 1 receptor 3 | 3
B (Shab) subfamily 2 | 2
Bradykinin receptor 2 | 2
CACNA1I subfamily 2 | 2
Calcitonin receptor 2 | 2
Calcium-sensing receptor 2 | 2
Cholecystokinin receptor 2 | 2
Corticotropin-releasing factor... 2 | 2
Glycoprotein hormone receptor 2 | 2
Gonadotrophin-releasing hormon... 2 | 2
KCNJ12 subfamily 2 | 2
Melatonin receptor 2 | 2
NR1-GRIN1 subfamily 2 | 2
Neuromedin U receptor 2 | 2
Neuropeptide FF-neuropeptide A... 2 | 2
Neuropeptide W-neuropeptide B ... 2 | 2
Neurotensin receptor 2 | 2
Parathyroid hormone receptor 2 | 2
Phosphorylase b kinase regulat... 2 | 2
Two pore calcium channel subfa... 2 | 2
V subfamily 2 | 2
CFTR transporter subfamily 1 | 1
CLCNKB subfamily 1 | 1
ClC-2-CLCN2 subfamily 1 | 1
ClC-3-CLCN3 subfamily 1 | 1
ClC-4-CLCN4 subfamily 1 | 1
ClC-5-CLCN5 subfamily 1 | 1
ClC-6-CLCN6 subfamily 1 | 1
ClC-7-CLCN7 subfamily 1 | 1
GRID2 subfamily 1 | 1
SCN4B family 1 | 1
SCNN1B subfamily 1 | 1
SCNN1D subfamily 1 | 1
SCNN1G subfamily 1 | 1

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