Development Level

Tclin 8 | 613

Collection

Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

cardiovascular system phenotyp... 1 | 36
decreased heart rate variabili... 1 | 13
increased circulating serum al... 1 | 22

Disease

Carcinoma 8 | 11,493
Eaton-Lambert syndrome 8 | 40
Multiple Sclerosis 8 | 540
psoriasis 5 | 6,694
Kidney cancer 4 | 2,613
lung carcinoma 4 | 2,843
Melanoma 3 | 711
Schizophrenia 3 | 1,160
Skin cancer 3 | 469
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
lung cancer 3 | 4,740
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
Astrocytoma, Pilocytic 2 | 3,081
Congenital myasthenic syndrome 5 2 | 11
Liver cancer 2 | 604
Long QT syndrome 2 | 39
Nonorganic psychosis 2 | 84
Psychotic Disorders 2 | 151
adult high grade glioma 2 | 3,801
glioblastoma 2 | 5,792
medulloblastoma, large-cell 2 | 6,241
Acquired metabolic disease 1 | 336
Acute contagious conjunctivitis 1 | 7
Adducted thumb 1 | 22
Adrenoleukodystrophy 1 | 29
Aortic root dilatation 1 | 11
Arrhythmias, Cardiac 1 | 19
Atrioventricular block 1 | 35
Background diabetic retinopathy 1 | 3
Bipolar I disorder 1 | 23
Breast Neoplasms 1 | 445
Broad hallux 1 | 29
Broad thumbs 1 | 28
Brugada syndrome 1 | 29
Bushy eyebrows 1 | 49
Campylobacteriosis 1 | 11
Cardiac Arrhythmia 1 | 103
Cardiac arrest 1 | 36
Cardiomyopathies 1 | 110
Cardiomyopathy 1 | 116
Cardioversion of Atrial Fibrillation 1 | 9
Catecholaminergic polymorphic ventricular tachycardia 1 | 12
Cell Transformation, Neoplastic 1 | 97
Charcot-Marie-Tooth disease X-linked dominant 1 1 | 4
Charcot-Marie-Tooth disease axonal type 2F 1 | 2
Charcot-Marie-Tooth disease type 1D 1 | 3
Charcot-Marie-Tooth disease type 2E 1 | 2
Coarse facial features 1 | 108
Colonic Neoplasms 1 | 142
Dilated cardiomyopathy 1D 1 | 3
Downturned corners of mouth 1 | 48
Exudative vitreoretinopathy 1 | 15
Familial atrial fibrillation 1 | 23
Fibromatosis, Gingival 1 | 8
Flat forehead 1 | 5
Full lower lip 1 | 64
Heart conduction disease 1 | 83
Hepatitis 1 | 67
Hepatitis B 1 | 108
Hereditary gingival fibromatosis 1 | 8
Hirsutism 1 | 47
Hyperextensible digits 1 | 7
Hypokalemia 1 | 52
Idiopathic gingival hyperplasia 1 | 8
Infantile onset 1 | 238
Late tooth eruption 1 | 61
Life-Threatening Ventricular Tachycardia 1 | 15
Long QT syndrome 1 1 | 20
Long Qt Syndrome 2 1 | 5
Mammary Neoplasms 1 | 425
Micronychia (disorder) 1 | 24
Muscular atrophy 1 | 71
Myopathic facies 1 | 13
Myopia 1 | 176
Neoplasms 1 | 63
Neoplastic Cell Transformation 1 | 89
Osteoporosis 1 | 363
Palpitations 1 | 18
Progressive mental retardation 1 | 37
Prolonged QT interval 1 | 15
Prominent lower lip 1 | 64
Romano-Ward Syndrome 1 | 12
Severe mental retardation (I.Q. 20-34) 1 | 99
Short QT syndrome 1 | 12
Short distal phalanges 1 | 50
Shortened QT interval 1 | 5
Spina bifida occulta 1 | 19
Sudden Cardiac Death 1 | 29
Sudden infant death syndrome 1 | 32
Syncope 1 | 22
Synophrys 1 | 40
Thickened facial skin with coarse facial features 1 | 108
Timothy syndrome 1 | 11
Torsades de Pointes 1 | 8
Ventricular Fibrillation 1 | 17
Wide nose 1 | 35
glioblastoma multiforme 1 | 142

Tissue

Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Digestive Tract 7 | 17,369
Liver and Pancreas 7 | 16,750
Blood and immune system 6 | 16,909
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Respiratory system 4 | 16,393
Cardiovascular System 3 | 15,192

Target Family

Ion Channel 8 | 344

DTO Protein Class (2)

H (Eag) subfamily 8 | 8
Olfactory receptor 421 | 421
TK group 93 | 93
Other group 87 | 87
CAMK group 77 | 77
CMGC group 70 | 70
AGC group 65 | 65
STE group 48 | 48
TKL group 45 | 45
Lipid kinase 30 | 30
Atypical group 28 | 28
Chemokine receptor 24 | 24
Taste 2 receptor 24 | 24
Gamma-aminobutyric acid recept... 19 | 19
Purinoceptor 18 | 18
Acetylcholine receptor subfami... 17 | 17
Other small molecule kinase 15 | 15
5-hydroxytryptamine receptor 12 | 12
CK1 group 12 | 12
Frizzled receptor 10 | 10
Mas proto-oncogene and Mas-rel... 10 | 10
Adrenoceptor 9 | 9
Carbohydrate kinase 9 | 9
A (Shaker) subfamily 8 | 8
Calcium-activated subfamily 8 | 8
LTrpC subfamily 8 | 8
Metabotropic glutamate recepto... 8 | 8
Histamine receptor 7 | 7
Nucleoside kinase 7 | 7
Dopamine receptor 6 | 6
Glucagon receptor 6 | 6
Lysophospholipid (LPA) recepto... 6 | 6
Melanin-concentrating hormone ... 6 | 6
Nucleotide kinase 6 | 6
RGC group 6 | 6
STrpC subfamily 6 | 6
TrpV subfamily 6 | 6
Vomeronasal receptor 6 | 6
5-hydroxytryptamine receptor s... 5 | 5
Acetylcholine receptor (muscar... 5 | 5
Adenosine receptor 5 | 5
Glycine receptor subfamily 5 | 5
KQT subfamily 5 | 5
Leukotriene receptor 5 | 5
Melanocortin receptor 5 | 5
Neuropeptide Y receptor 5 | 5
Angiotensin receptor 4 | 4
C (Shaw) subfamily 4 | 4
Cannabinoid receptor 4 | 4
Free fatty acid receptor 4 | 4
G subfamily 4 | 4
GABA-B receptor 4 | 4
KCNE subfamily 4 | 4
Latrophilin receptor 4 | 4
Proteinase-activated receptor 4 | 4
Anaphylatoxin receptor 3 | 3
Bombesin receptor 3 | 3
Cadherin EGF LAG (CELSR) recep... 3 | 3
D (Shal) subfamily 3 | 3
Endothelin receptor 3 | 3
Formyl peptide receptor 3 | 3
Galanin receptor 3 | 3
Hydroxycarboxylic acid recepto... 3 | 3
Polycystin subfamily 3 | 3
S subfamily 3 | 3
Tachykinin receptor 3 | 3
Taste 1 receptor 3 | 3
B (Shab) subfamily 2 | 2
Bradykinin receptor 2 | 2
CACNA1I subfamily 2 | 2
Calcitonin receptor 2 | 2
Calcium-sensing receptor 2 | 2
Cholecystokinin receptor 2 | 2
Corticotropin-releasing factor... 2 | 2
Glycoprotein hormone receptor 2 | 2
Gonadotrophin-releasing hormon... 2 | 2
KCNJ12 subfamily 2 | 2
Melatonin receptor 2 | 2
NR1-GRIN1 subfamily 2 | 2
Neuromedin U receptor 2 | 2
Neuropeptide FF-neuropeptide A... 2 | 2
Neuropeptide W-neuropeptide B ... 2 | 2
Neurotensin receptor 2 | 2
Parathyroid hormone receptor 2 | 2
Phosphorylase b kinase regulat... 2 | 2
Two pore calcium channel subfa... 2 | 2
V subfamily 2 | 2
CFTR transporter subfamily 1 | 1
CLCNKB subfamily 1 | 1
ClC-2-CLCN2 subfamily 1 | 1
ClC-3-CLCN3 subfamily 1 | 1
ClC-4-CLCN4 subfamily 1 | 1
ClC-5-CLCN5 subfamily 1 | 1
ClC-6-CLCN6 subfamily 1 | 1
ClC-7-CLCN7 subfamily 1 | 1
GRID2 subfamily 1 | 1
SCN4B family 1 | 1
SCNN1B subfamily 1 | 1
SCNN1D subfamily 1 | 1
SCNN1G subfamily 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily H member 3 KCNH3 Tclin Ion Channel -1.07866 11.8 67
Potassium voltage-gated channel subfamily H member 5 KCNH5 Tclin Ion Channel -1.20155 17.8 40
Potassium voltage-gated channel subfamily H member 2 KCNH2 Tclin Ion Channel -3.22575 1653.9 243
Potassium voltage-gated channel subfamily H member 4 KCNH4 Tclin Ion Channel -1.41269 24.4 78
Potassium voltage-gated channel subfamily H member 1 KCNH1 Tclin Ion Channel -2.86111 714.2 150
Potassium voltage-gated channel subfamily H member 6 KCNH6 Tclin Ion Channel -1.70198 48.6 99
Potassium voltage-gated channel subfamily H member 8 KCNH8 Tclin Ion Channel -0.66110 4.85 64
Potassium voltage-gated channel subfamily H member 7 KCNH7 Tclin Ion Channel -0.83699 6.96 121