Development Level

Tchem 5 | 1,598
Tbio 4 | 11,445

IMPC Phenotype

abnormal bone structure 1 | 187
decreased bone mineral density 1 | 126
decreased neutrophil cell numb... 1 | 42
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased lymphocyte cell numb... 1 | 32
preweaning lethality, complete... 1 | 979
thick ventricular wall 1 | 7
thin ventricular wall 1 | 24

Disease

Carcinoma 6 | 11,493
lung cancer 4 | 4,740
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Bipolar Disorder 2 | 666
Diabetes Mellitus, Experimental 2 | 108
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Mood Disorders 2 | 184
Myocardial Ischemia 2 | 169
Neuropathy 2 | 261
Obesity 2 | 678
Peripheral Neuropathy 2 | 134
Type 2 diabetes mellitus 2 | 272
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
dermatomyositis 2 | 966
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung carcinoma 2 | 2,843
medulloblastoma 2 | 720
non-small cell lung cancer 2 | 2,890
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
Abnormality of the immune system 1 | 18
Acquired metabolic disease 1 | 336
Adenocarcinoma of lung 1 | 142
Alopecia areata 1 | 41
Arsenic Poisoning 1 | 62
Arthrogryposis 1 | 54
Atypical chronic myeloid leukemia 1 | 4
Autoimmune polyendocrine syndrome type 1 1 | 9
Axial hypotonia 1 | 46
Batten disease 1 | 13
Bilateral ptosis 1 | 9
Blepharoptosis 1 | 231
Celiac disease 1 | 116
Charcot-Marie-Tooth disease 1 | 62
Cholecystitis 1 | 18
Cholelithiasis 1 | 33
Congenital Heart Defects 1 | 58
Congenital heart disease 1 | 93
Decreased motor NCV 1 | 22
Decreased tendon reflex 1 | 122
Dehydration 1 | 40
Depletion of large myelinated fibers 1 | 7
Dermatologic disorders 1 | 93
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Difficulty walking 1 | 28
Disease Models, Animal 1 | 155
Distal limb muscle weakness due to peripheral neuropathy 1 | 62
Downturned corners of mouth 1 | 48
Epilepsies, Myoclonic 1 | 32
Generalized myoclonic seizures 1 | 30
Gestational diabetes 1 | 26
Hand deformities 1 | 32
Hyperglycemia 1 | 137
Hyperinsulinism 1 | 133
Hypsarrhythmia 1 | 25
Icterus 1 | 82
Increased bilirubin level (finding) 1 | 18
Insulin Resistance 1 | 72
Insulinoma 1 | 24
Liver Cirrhosis, Experimental 1 | 769
Low Birth Weights 1 | 69
Metabolic syndrome X 1 | 52
Motor delay 1 | 147
Muscle Weakness 1 | 170
Myoclonic Epilepsies, Progressive 1 | 44
No development of motor milestones 1 | 147
Peripheral hypomyelination 1 | 7
Poland syndrome 1 | 14
Prenatal onset 1 | 139
Progressive disorder 1 | 142
Prominent metopic ridge 1 | 15
Reticulocytosis 1 | 20
Retinal Diseases 1 | 55
Rett syndrome 1 | 18
Shipyard eye 1 | 15
Skin Diseases 1 | 71
Small for gestational age (disorder) 1 | 69
Tonic - clonic seizures 1 | 44
Weight decreased 1 | 103
maturity-onset diabetes of the young 1 | 32

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Kinase 7 | 634
Non-IDG 2 | 12,091

DTO Protein Class (2)

Carbohydrate kinase 9 | 9
Olfactory receptor 421 | 421
TK group 93 | 93
Other group 87 | 87
CAMK group 77 | 77
CMGC group 70 | 70
AGC group 65 | 65
STE group 48 | 48
TKL group 45 | 45
Lipid kinase 30 | 30
Atypical group 28 | 28
Chemokine receptor 24 | 24
Taste 2 receptor 24 | 24
Gamma-aminobutyric acid recept... 19 | 19
Purinoceptor 18 | 18
Acetylcholine receptor subfami... 17 | 17
Other small molecule kinase 15 | 15
5-hydroxytryptamine receptor 12 | 12
CK1 group 12 | 12
Frizzled receptor 10 | 10
Mas proto-oncogene and Mas-rel... 10 | 10
Adrenoceptor 9 | 9
A (Shaker) subfamily 8 | 8
Calcium-activated subfamily 8 | 8
H (Eag) subfamily 8 | 8
LTrpC subfamily 8 | 8
Metabotropic glutamate recepto... 8 | 8
Histamine receptor 7 | 7
Nucleoside kinase 7 | 7
Dopamine receptor 6 | 6
Glucagon receptor 6 | 6
Lysophospholipid (LPA) recepto... 6 | 6
Melanin-concentrating hormone ... 6 | 6
Nucleotide kinase 6 | 6
RGC group 6 | 6
STrpC subfamily 6 | 6
TrpV subfamily 6 | 6
Vomeronasal receptor 6 | 6
5-hydroxytryptamine receptor s... 5 | 5
Acetylcholine receptor (muscar... 5 | 5
Adenosine receptor 5 | 5
Glycine receptor subfamily 5 | 5
KQT subfamily 5 | 5
Leukotriene receptor 5 | 5
Melanocortin receptor 5 | 5
Neuropeptide Y receptor 5 | 5
Angiotensin receptor 4 | 4
C (Shaw) subfamily 4 | 4
Cannabinoid receptor 4 | 4
Free fatty acid receptor 4 | 4
G subfamily 4 | 4
GABA-B receptor 4 | 4
KCNE subfamily 4 | 4
Latrophilin receptor 4 | 4
Proteinase-activated receptor 4 | 4
Anaphylatoxin receptor 3 | 3
Bombesin receptor 3 | 3
Cadherin EGF LAG (CELSR) recep... 3 | 3
D (Shal) subfamily 3 | 3
Endothelin receptor 3 | 3
Formyl peptide receptor 3 | 3
Galanin receptor 3 | 3
Hydroxycarboxylic acid recepto... 3 | 3
Polycystin subfamily 3 | 3
S subfamily 3 | 3
Tachykinin receptor 3 | 3
Taste 1 receptor 3 | 3
B (Shab) subfamily 2 | 2
Bradykinin receptor 2 | 2
CACNA1I subfamily 2 | 2
Calcitonin receptor 2 | 2
Calcium-sensing receptor 2 | 2
Cholecystokinin receptor 2 | 2
Corticotropin-releasing factor... 2 | 2
Glycoprotein hormone receptor 2 | 2
Gonadotrophin-releasing hormon... 2 | 2
KCNJ12 subfamily 2 | 2
Melatonin receptor 2 | 2
NR1-GRIN1 subfamily 2 | 2
Neuromedin U receptor 2 | 2
Neuropeptide FF-neuropeptide A... 2 | 2
Neuropeptide W-neuropeptide B ... 2 | 2
Neurotensin receptor 2 | 2
Parathyroid hormone receptor 2 | 2
Phosphorylase b kinase regulat... 2 | 2
Two pore calcium channel subfa... 2 | 2
V subfamily 2 | 2
CFTR transporter subfamily 1 | 1
CLCNKB subfamily 1 | 1
ClC-2-CLCN2 subfamily 1 | 1
ClC-3-CLCN3 subfamily 1 | 1
ClC-4-CLCN4 subfamily 1 | 1
ClC-5-CLCN5 subfamily 1 | 1
ClC-6-CLCN6 subfamily 1 | 1
ClC-7-CLCN7 subfamily 1 | 1
GRID2 subfamily 1 | 1
SCN4B family 1 | 1
SCNN1B subfamily 1 | 1
SCNN1D subfamily 1 | 1
SCNN1G subfamily 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tachykinin-4 TAC4 Tbio Non-IDG -1.56554 37.9 57
Protein Hook homolog 1 HOOK1 Tbio Non-IDG -1.16190 13.1 187
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 PFKFB2 Tchem Kinase -1.65270 45.8 315
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 PFKFB1 Tbio Kinase -1.33284 17.6 214
Ketohexokinase KHK Tchem Kinase -1.99770 98.6 319
ATP-dependent 6-phosphofructokinase, liver type PFKL Tbio Kinase -2.07015 107.6 240
Glucokinase GCK Tchem Kinase -2.90428 758.6 336
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 PFKFB3 Tchem Kinase -2.28070 206.0 228
Hexokinase-1 HK1 Tchem Kinase -2.58967 375.7 571