Development Level

Tclin 8 | 613

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal seminal vesicle morph... 1 | 114
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
increased mean platelet volume 1 | 45
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 8 | 11,493
Eaton-Lambert syndrome 8 | 40
Multiple Sclerosis 8 | 540
Kidney cancer 6 | 2,613
Episodic ataxia 5 | 22
ependymoma 3 | 4,679
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
pituitary cancer 3 | 1,972
Astrocytoma, Pilocytic 2 | 3,081
Cerebellar Ataxia 2 | 304
Epilepsy 2 | 792
Liver cancer 2 | 604
Tremor 2 | 113
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
lung carcinoma 2 | 2,843
oligodendroglioma 2 | 2,850
osteosarcoma 2 | 7,950
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 1 | 21
Atrial Fibrillation 1 | 124
Atrial Fibrillation, Familial, 7 1 | 1
Babinski Reflex 1 | 100
Benign neonatal seizures 1 | 4
Blurred vision 1 | 19
Creatine phosphokinase serum increased 1 | 110
Diaphragmatic Hernia 1 | 40
Dizziness 1 | 26
Dysarthria 1 | 192
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 32 1 | 1
Electromyogram abnormal 1 | 49
Elevated creatine kinase 1 | 110
Epileptic encephalopathy 1 | 26
Episodic Ataxia, Type 1 1 | 1
Episodic ataxia type 1 1 | 4
Familial atrial fibrillation 1 | 23
Hand deformities 1 | 32
Headache 1 | 37
Heart disease 1 | 306
Hereditary continuous muscle fiber activity 1 | 1
Hernia, Diaphragmatic 1 | 40
Highly variable severity 1 | 157
Hyperreflexia 1 | 209
Hypertension 1 | 396
Hypertension, Pulmonary 1 | 37
Infantile onset 1 | 238
Intellectual disability 1 | 1,016
Language Development Disorders 1 | 11
Long QT syndrome 1 | 39
Migraine 1 | 83
Movement Disorders 1 | 55
Myasthenia gravis 1 | 23
Myoclonus 1 | 74
Myokymia 1 | 6
Neurodegenerative disease 1 | 414
Palpitations 1 | 18
Panic disorder 1 | 61
Paroxysmal atrial fibrillation 1 | 14
Primary pulmonary hypertension 1 | 14
Seizures 1 | 596
Slurred speech 1 | 7
Spastic gait 1 | 23
Tabes dorsalis 1 | 6
Thymoma 1 | 16
Type 1 muscle fiber predominance 1 | 10
Type 2 diabetes mellitus 1 | 272
Variable expressivity 1 | 157
Vertigo 1 | 29
chorea-acanthocytosis 1 | 12
colon cancer 1 | 1,478
diabetes mellitus 1 | 1,728
interstitial cystitis 1 | 2,312
invasive ductal carcinoma 1 | 2,951
ovarian cancer 1 | 8,520
sonic hedgehog group medulloblastoma 1 | 467
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Endocrine System 7 | 18,159
Digestive Tract 6 | 17,369
Female tissues 6 | 17,400
Nervous System 6 | 16,725
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Respiratory system 5 | 16,393

Target Family

Ion Channel 8 | 344

DTO Protein Class (2)

A (Shaker) subfamily 8 | 8
Olfactory receptor 421 | 421
TK group 93 | 93
Other group 87 | 87
CAMK group 77 | 77
CMGC group 70 | 70
AGC group 65 | 65
STE group 48 | 48
TKL group 45 | 45
Lipid kinase 30 | 30
Atypical group 28 | 28
Chemokine receptor 24 | 24
Taste 2 receptor 24 | 24
Gamma-aminobutyric acid recept... 19 | 19
Purinoceptor 18 | 18
Acetylcholine receptor subfami... 17 | 17
Other small molecule kinase 15 | 15
5-hydroxytryptamine receptor 12 | 12
CK1 group 12 | 12
Frizzled receptor 10 | 10
Mas proto-oncogene and Mas-rel... 10 | 10
Adrenoceptor 9 | 9
Carbohydrate kinase 9 | 9
Calcium-activated subfamily 8 | 8
H (Eag) subfamily 8 | 8
LTrpC subfamily 8 | 8
Metabotropic glutamate recepto... 8 | 8
Histamine receptor 7 | 7
Nucleoside kinase 7 | 7
Dopamine receptor 6 | 6
Glucagon receptor 6 | 6
Lysophospholipid (LPA) recepto... 6 | 6
Melanin-concentrating hormone ... 6 | 6
Nucleotide kinase 6 | 6
RGC group 6 | 6
STrpC subfamily 6 | 6
TrpV subfamily 6 | 6
Vomeronasal receptor 6 | 6
5-hydroxytryptamine receptor s... 5 | 5
Acetylcholine receptor (muscar... 5 | 5
Adenosine receptor 5 | 5
Glycine receptor subfamily 5 | 5
KQT subfamily 5 | 5
Leukotriene receptor 5 | 5
Melanocortin receptor 5 | 5
Neuropeptide Y receptor 5 | 5
Angiotensin receptor 4 | 4
C (Shaw) subfamily 4 | 4
Cannabinoid receptor 4 | 4
Free fatty acid receptor 4 | 4
G subfamily 4 | 4
GABA-B receptor 4 | 4
KCNE subfamily 4 | 4
Latrophilin receptor 4 | 4
Proteinase-activated receptor 4 | 4
Anaphylatoxin receptor 3 | 3
Bombesin receptor 3 | 3
Cadherin EGF LAG (CELSR) recep... 3 | 3
D (Shal) subfamily 3 | 3
Endothelin receptor 3 | 3
Formyl peptide receptor 3 | 3
Galanin receptor 3 | 3
Hydroxycarboxylic acid recepto... 3 | 3
Polycystin subfamily 3 | 3
S subfamily 3 | 3
Tachykinin receptor 3 | 3
Taste 1 receptor 3 | 3
B (Shab) subfamily 2 | 2
Bradykinin receptor 2 | 2
CACNA1I subfamily 2 | 2
Calcitonin receptor 2 | 2
Calcium-sensing receptor 2 | 2
Cholecystokinin receptor 2 | 2
Corticotropin-releasing factor... 2 | 2
Glycoprotein hormone receptor 2 | 2
Gonadotrophin-releasing hormon... 2 | 2
KCNJ12 subfamily 2 | 2
Melatonin receptor 2 | 2
NR1-GRIN1 subfamily 2 | 2
Neuromedin U receptor 2 | 2
Neuropeptide FF-neuropeptide A... 2 | 2
Neuropeptide W-neuropeptide B ... 2 | 2
Neurotensin receptor 2 | 2
Parathyroid hormone receptor 2 | 2
Phosphorylase b kinase regulat... 2 | 2
Two pore calcium channel subfa... 2 | 2
V subfamily 2 | 2
CFTR transporter subfamily 1 | 1
CLCNKB subfamily 1 | 1
ClC-2-CLCN2 subfamily 1 | 1
ClC-3-CLCN3 subfamily 1 | 1
ClC-4-CLCN4 subfamily 1 | 1
ClC-5-CLCN5 subfamily 1 | 1
ClC-6-CLCN6 subfamily 1 | 1
ClC-7-CLCN7 subfamily 1 | 1
GRID2 subfamily 1 | 1
SCN4B family 1 | 1
SCNN1B subfamily 1 | 1
SCNN1D subfamily 1 | 1
SCNN1G subfamily 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily A member 7 KCNA7 Tclin Ion Channel -0.87978 7.43 59
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
Potassium voltage-gated channel subfamily A member 1 KCNA1 Tclin Ion Channel -2.59564 379.1 313
Potassium voltage-gated channel subfamily A member 3 KCNA3 Tclin Ion Channel -2.69107 522.2 286
Potassium voltage-gated channel subfamily A member 4 KCNA4 Tclin Ion Channel -2.32803 199.8 155
Potassium voltage-gated channel subfamily A member 5 KCNA5 Tclin Ion Channel -2.61528 428.3 209
Potassium voltage-gated channel subfamily A member 6 KCNA6 Tclin Ion Channel -1.60675 36.8 86
Potassium voltage-gated channel subfamily A member 10 KCNA10 Tclin Ion Channel -1.09844 13.3 65