Development Level

Tclin 8 | 613
Tchem 4 | 1,598

Collection

GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

abnormal behavioral response t... 2 | 66
decreased total body fat amoun... 2 | 207
increased circulating sodium l... 2 | 71
abnormal tail length 1 | 3
cardiovascular system phenotyp... 1 | 36
decreased anxiety-related resp... 1 | 12
decreased lean body mass 1 | 135
impaired pupillary reflex 1 | 26
increased circulating chloride... 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Migraine 12 | 83
Schizophrenia 12 | 1,160
Carcinoma 11 | 11,493
Major Depressive Disorder 9 | 301
Bipolar Disorder 8 | 666
Depressive disorder 8 | 409
Mood Disorders 8 | 184
Alzheimer's disease 6 | 658
Autistic Disorder 6 | 364
Mental Depression 6 | 333
Alcohol dependence 5 | 107
Alcoholic Intoxication, Chronic 5 | 289
Amnestic disorder 5 | 35
Cluster headache syndrome 5 | 8
Parkinson's disease 5 | 392
Substance abuse 5 | 59
malignant mesothelioma 5 | 3,232
obsessive-compulsive disorder 5 | 61
psoriasis 5 | 6,694
Attention deficit hyperactivity disorder 4 | 278
Dementia 4 | 175
Generalized anxiety disorder 4 | 29
Migraine Prevention 4 | 23
Obesity 4 | 678
Personality disorder 4 | 25
Unipolar Depression 4 | 250
Vascular headache 4 | 7
Bipolar affective disorder, current episode manic 3 | 13
Cluster Headache Prevention 3 | 6
Cocaine-Related Disorders 3 | 92
Hyperprolactinemia 3 | 27
Hypoactive sexual desire disorder 3 | 8
Irritable bowel syndrome 3 | 60
Kidney cancer 3 | 2,613
Memory Disorders 3 | 40
Mixed bipolar I disorder 3 | 9
Panic disorder 3 | 61
Premature ejaculation 3 | 16
Psychotic Disorders 3 | 151
Treatment-resistant schizophrenia 3 | 6
astrocytic glioma 3 | 2,597
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
osteosarcoma 3 | 7,950
primitive neuroectodermal tumor 3 | 3,035
Acromegaly 2 | 51
Agitation associated with Bipolar Mania 2 | 5
Agitation associated with Schizophrenia 2 | 5
Alcohol abuse 2 | 50
Amphetamine-Related Disorders 2 | 74
Astrocytoma, Pilocytic 2 | 3,081
Bipolar disorder in remission 2 | 19
Chronic thromboembolic pulmonary hypertension 2 | 4
Cocaine abuse 2 | 19
Constipation 2 | 181
Depression Treatment Adjunct 2 | 5
Diarrhea 2 | 253
Drug psychosis 2 | 7
Dyspepsia 2 | 33
Eating disorder 2 | 26
Epilepsy 2 | 792
Fever 2 | 138
Gastroparesis 2 | 22
Heart disease 2 | 306
Hyperactive behavior 2 | 91
Hyperkinesis 2 | 32
Hypertension 2 | 396
Hypotension 2 | 82
Infantile autism 2 | 4
Lack or loss of sexual desire 2 | 3
Learning Disorders 2 | 29
Migraine Disorders 2 | 76
Motion sickness 2 | 21
Pain 2 | 103
Pain agnosia 2 | 104
Postabortal Hemorrhage 2 | 3
Postpartum hemorrhage 2 | 6
Psychoses, Substance-Induced 2 | 17
Schizoaffective Disorder 2 | 55
Seasonal affective disorder 2 | 28
Seizures 2 | 596
Sexual dysfunction 2 | 9
Single major depressive episode 2 | 8
Sudden infant death syndrome 2 | 32
adult high grade glioma 2 | 3,801
group 3 medulloblastoma 2 | 4,104
non diabetic and post-ischemic heart failure 2 | 200
ovarian cancer 2 | 8,520
post-traumatic stress disorder 2 | 40
pulmonary arterial hypertension 2 | 75
substance-related disorder 2 | 162
Anorexia 1 | 43
Anxiety Disorders 1 | 38
Chronic schizophrenia 1 | 16
Ileus 1 | 19
Nasal congestion 1 | 21
Nonorganic psychosis 1 | 84

Tissue

Nervous System 12 | 16,725
Endocrine System 11 | 18,159
Digestive Tract 10 | 17,369
Female tissues 10 | 17,400
Blood and immune system 9 | 16,909
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Cardiovascular System 8 | 15,192
Urinary Tract 8 | 16,678

Target Family

GPCR 12 | 408

DTO Protein Class (2)

5-hydroxytryptamine receptor 12 | 12
Olfactory receptor 421 | 421
TK group 93 | 93
Other group 87 | 87
CAMK group 77 | 77
CMGC group 70 | 70
AGC group 65 | 65
STE group 48 | 48
TKL group 45 | 45
Lipid kinase 30 | 30
Atypical group 28 | 28
Chemokine receptor 24 | 24
Taste 2 receptor 24 | 24
Gamma-aminobutyric acid recept... 19 | 19
Purinoceptor 18 | 18
Acetylcholine receptor subfami... 17 | 17
Other small molecule kinase 15 | 15
CK1 group 12 | 12
Frizzled receptor 10 | 10
Mas proto-oncogene and Mas-rel... 10 | 10
Adrenoceptor 9 | 9
Carbohydrate kinase 9 | 9
A (Shaker) subfamily 8 | 8
Calcium-activated subfamily 8 | 8
H (Eag) subfamily 8 | 8
LTrpC subfamily 8 | 8
Metabotropic glutamate recepto... 8 | 8
Histamine receptor 7 | 7
Nucleoside kinase 7 | 7
Dopamine receptor 6 | 6
Glucagon receptor 6 | 6
Lysophospholipid (LPA) recepto... 6 | 6
Melanin-concentrating hormone ... 6 | 6
Nucleotide kinase 6 | 6
RGC group 6 | 6
STrpC subfamily 6 | 6
TrpV subfamily 6 | 6
Vomeronasal receptor 6 | 6
5-hydroxytryptamine receptor s... 5 | 5
Acetylcholine receptor (muscar... 5 | 5
Adenosine receptor 5 | 5
Glycine receptor subfamily 5 | 5
KQT subfamily 5 | 5
Leukotriene receptor 5 | 5
Melanocortin receptor 5 | 5
Neuropeptide Y receptor 5 | 5
Angiotensin receptor 4 | 4
C (Shaw) subfamily 4 | 4
Cannabinoid receptor 4 | 4
Free fatty acid receptor 4 | 4
G subfamily 4 | 4
GABA-B receptor 4 | 4
KCNE subfamily 4 | 4
Latrophilin receptor 4 | 4
Proteinase-activated receptor 4 | 4
Anaphylatoxin receptor 3 | 3
Bombesin receptor 3 | 3
Cadherin EGF LAG (CELSR) recep... 3 | 3
D (Shal) subfamily 3 | 3
Endothelin receptor 3 | 3
Formyl peptide receptor 3 | 3
Galanin receptor 3 | 3
Hydroxycarboxylic acid recepto... 3 | 3
Polycystin subfamily 3 | 3
S subfamily 3 | 3
Tachykinin receptor 3 | 3
Taste 1 receptor 3 | 3
B (Shab) subfamily 2 | 2
Bradykinin receptor 2 | 2
CACNA1I subfamily 2 | 2
Calcitonin receptor 2 | 2
Calcium-sensing receptor 2 | 2
Cholecystokinin receptor 2 | 2
Corticotropin-releasing factor... 2 | 2
Glycoprotein hormone receptor 2 | 2
Gonadotrophin-releasing hormon... 2 | 2
KCNJ12 subfamily 2 | 2
Melatonin receptor 2 | 2
NR1-GRIN1 subfamily 2 | 2
Neuromedin U receptor 2 | 2
Neuropeptide FF-neuropeptide A... 2 | 2
Neuropeptide W-neuropeptide B ... 2 | 2
Neurotensin receptor 2 | 2
Parathyroid hormone receptor 2 | 2
Phosphorylase b kinase regulat... 2 | 2
Two pore calcium channel subfa... 2 | 2
V subfamily 2 | 2
CFTR transporter subfamily 1 | 1
CLCNKB subfamily 1 | 1
ClC-2-CLCN2 subfamily 1 | 1
ClC-3-CLCN3 subfamily 1 | 1
ClC-4-CLCN4 subfamily 1 | 1
ClC-5-CLCN5 subfamily 1 | 1
ClC-6-CLCN6 subfamily 1 | 1
ClC-7-CLCN7 subfamily 1 | 1
GRID2 subfamily 1 | 1
SCN4B family 1 | 1
SCNN1B subfamily 1 | 1
SCNN1D subfamily 1 | 1
SCNN1G subfamily 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-hydroxytryptamine receptor 4 HTR4 Tclin GPCR -2.87235 796.4 248
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
5-hydroxytryptamine receptor 6 HTR6 Tchem GPCR -2.31880 213.2 64
5-hydroxytryptamine receptor 1F HTR1F Tchem GPCR -2.39159 244.1 131
5-hydroxytryptamine receptor 1A HTR1A Tclin GPCR -3.67718 4891.4 254
5-hydroxytryptamine receptor 5A HTR5A Tchem GPCR -1.67734 48.8 246
5-hydroxytryptamine receptor 2A HTR2A Tclin GPCR -3.33563 2152.8 231
5-hydroxytryptamine receptor 7 HTR7 Tclin GPCR -4.15964 13643.7 259
5-hydroxytryptamine receptor 1D HTR1D Tclin GPCR -2.54328 350.8 140
5-hydroxytryptamine receptor 1B HTR1B Tclin GPCR -3.03042 1068.4 211