Development Level

Tchem 18 | 1,598
Tbio 3 | 11,445
Tclin 3 | 613

IMPC Phenotype

limb grasping 2 | 41
abnormal forelimb morphology 1 | 2
abnormal gait 1 | 69
abnormal locomotor activation 1 | 16
abnormal response to new envir... 1 | 10
corneal vascularization 1 | 6
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating glycerol... 1 | 16
decreased circulating triglyce... 1 | 79
decreased prepulse inhibition 1 | 82
hyperactivity 1 | 148
increased aggression 1 | 4
increased lean body mass 1 | 172
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
preweaning lethality, complete... 1 | 979
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 21 | 11,493
Kidney cancer 13 | 2,613
medulloblastoma, large-cell 8 | 6,241
atypical teratoid / rhabdoid tumor 7 | 5,112
glioblastoma 7 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
lung cancer 7 | 4,740
osteosarcoma 7 | 7,950
ovarian cancer 7 | 8,520
psoriasis 7 | 6,694
Dentin sensitivity 6 | 14
Hypertension 6 | 396
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
Cancer 5 | 2,499
Melanoma 5 | 711
adult high grade glioma 5 | 3,801
cystic fibrosis 5 | 1,696
lung adenocarcinoma 5 | 2,716
malignant mesothelioma 5 | 3,232
Breast cancer 4 | 3,578
Neuropathy 4 | 261
cutaneous lupus erythematosus 4 | 1,057
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
ulcerative colitis 4 | 1,819
Asthma 3 | 385
Atopic dermatitis 3 | 952
Bipolar Disorder 3 | 666
Gangliosidosis 3 | 20
Hyperalgesia 3 | 83
Kidney disease 3 | 430
Migraine 3 | 83
Neurodegenerative disease 3 | 414
Pain 3 | 103
Pain agnosia 3 | 104
adrenocortical carcinoma 3 | 1,428
colon cancer 3 | 1,478
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
subependymal giant cell astrocytoma 3 | 2,287
Allergic hypersensitivity disease 2 | 126
Alzheimer's disease 2 | 658
Arthritic Pain 2 | 5
Astrocytoma, Pilocytic 2 | 3,081
Atherosclerosis 2 | 291
Backache 2 | 8
Cough 2 | 23
Degenerative polyarthritis 2 | 115
Dementia 2 | 175
Duchenne muscular dystrophy 2 | 601
Endometrial cancer 2 | 311
Hypertensive disease 2 | 292
Hypervitaminosis D 2 | 8
Inflammation 2 | 120
Irritable bowel syndrome 2 | 60
Osteoarthritis 2 | 184
Pain disorder 2 | 15
Pick disease 2 | 1,894
Rickets 2 | 49
Schizophrenia 2 | 1,160
Sneezing 2 | 12
Sprains and Strains 2 | 6
Vascular disease 2 | 319
active Crohn's disease 2 | 922
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
gastric cancer 2 | 459
group 4 medulloblastoma 2 | 1,855
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group B ependymoma 2 | 416
primary Sjogren syndrome 2 | 735
primitive neuroectodermal tumor 2 | 3,035
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis 2 | 2,010
Amyloidosis 1 | 67
Autosomal dominant nonsyndromic deafness 25 1 | 6
Beriberi 1 | 12
Bone disease 1 | 10
Chronic Kidney Diseases 1 | 13
Chronic Obstructive Airway Disease 1 | 37
Common Migraine 1 | 7
Cri-Du-Chat syndrome 1 | 16
Disturbance in mood 1 | 3
Epilepsy, Temporal Lobe 1 | 23
Fascioliasis 1 | 17
Gait, Unsteady 1 | 29
Glycoproteinosis 1 | 12
Iris disease 1 | 10
Migraine without Aura 1 | 11
Neoplasms 1 | 63
Progressive renal failure 1 | 13
Pulmonary Disease, Chronic Obstructive 1 | 31
Ureteral obstruction 1 | 33

Tissue

Endocrine System 23 | 18,159
Urinary Tract 23 | 16,678
Digestive Tract 22 | 17,369
Liver and Pancreas 22 | 16,750
Male tissues 21 | 17,142
Skin and soft tissues 21 | 17,230
Blood and immune system 20 | 16,909
Nervous System 20 | 16,725
Female tissues 19 | 17,400
Respiratory system 19 | 16,393
Cardiovascular System 16 | 15,192

Target Family

Ion Channel 23 | 344
Non-IDG 1 | 12,091

DTO Protein Class (1)

Transient receptor potential c... 24 | 24
Class A rhodopsin like 749 | 749
Protein kinase 535 | 535
Non-protein kinase 67 | 67
Potassium channel family 52 | 52
Neurotransmitter receptor, cys... 47 | 47
Adhesion class 33 | 33
Class C metabotropic glutamate... 23 | 23
Glutamate-gated ion channel (... 19 | 19
Class B secretin like 16 | 16
Inward rectifier-type potassiu... 16 | 16
Two pore domain potassium chan... 15 | 15
Calcium channel alpha-1 subuni... 13 | 13
Class F frizzled-type 12 | 12
Cyclic nucleotide-gated cation... 10 | 10
Sodium channel family 10 | 10
Amiloride-sensitive sodium cha... 9 | 9
Chloride channel family 9 | 9
Calcium channel auxiliary subu... 8 | 8
3-ketosteroid receptors 7 | 7
Atp-gated p2x receptor cation ... 7 | 7
Intracellular chloride channel... 6 | 6
Polycystin cation channel (pcc... 6 | 6
Ryanodine-inositol 1,4,5-triph... 6 | 6
Transmembrane channel (TMC) fa... 6 | 6
Calcium-dependent chloride cha... 5 | 5
Fxyd family 5 | 5
Anion channel-forming bestroph... 4 | 4
Calcium channel auxiliary subu... 4 | 4
Calcium channel auxiliary subu... 4 | 4
Calcium homeostasis modulator ... 4 | 4
Calcium-activated potassium ch... 4 | 4
Cation channel sperm-associate... 4 | 4
Epithelial chloride channel (e... 4 | 4
Other 7TM proteins 4 | 4
Sodium channel auxiliary subun... 4 | 4
Vitamin d receptor-like recept... 4 | 4
Anion channel tweety (tweety) ... 3 | 3
Coup-tf-like receptors 3 | 3
Estrogen-related receptors 3 | 3
Gap junction-forming innexin (... 3 | 3
Liver x receptor-like receptor... 3 | 3
Nerve growth factor ib-like re... 3 | 3
Peroxisome proliferator-activa... 3 | 3
Phagocyte (gp91(phox)) nadph o... 3 | 3
Retinoic acid receptors 3 | 3
Retinoic acid-related orphans 3 | 3
Retinoid x receptors 3 | 3
Voltage-gated potassium channe... 3 | 3
Dax-like receptors 2 | 2
Estrogen receptors 2 | 2
FAM26 family 2 | 2
Fushi tarazu f1-like receptors 2 | 2
Golgi pH regulator family 2 | 2
Hepatocyte nuclear factor-4 re... 2 | 2
Mechanical nociceptor, piezo (... 2 | 2
Phospholemman (plm) family 2 | 2
Rev-erb receptors 2 | 2
SLC26A-SulP transporter family 2 | 2
Tailless-like receptors 2 | 2
Testicular receptors 2 | 2
Thyroid hormone receptors 2 | 2
Tmem38 family 2 | 2
Unclassified protein 2 | 2
ABCC family 1 | 1
Calcium release-activated calc... 1 | 1
Cation-nonselective channel fa... 1 | 1
Germ cell nuclear factor recep... 1 | 1
Intracellular chloride channel... 1 | 1
MCU family 1 | 1
Membrane protein mlc1 family 1 | 1
PMP-22-EMP-MP20 family 1 | 1
The phagocyte (gp91(phox)) nad... 1 | 1
Voltage-gated proton channel (... 1 | 1

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