Development Level

Tclin 41 | 613
Tchem 6 | 1,598
Tbio 5 | 11,445

Collection

Ion Channel: IDG Consortium (T... 17 | 99

IMPC Phenotype

abnormal behavior 5 | 298
hyperactivity 4 | 148
abnormal behavioral response t... 2 | 66
increased bone mineral content 2 | 108
increased mean corpuscular vol... 2 | 92
abnormal brain morphology 1 | 13
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal locomotor behavior 1 | 24
abnormal seminal vesicle morph... 1 | 114
cardiovascular system phenotyp... 1 | 36
decreased cardiac stroke volum... 1 | 6
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased heart rate variabili... 1 | 13
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydroencephaly 1 | 14
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 22
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased vertical activity 1 | 24
kyphosis 1 | 5
preweaning lethality, complete... 1 | 979
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened QT interval 1 | 4
shortened ST segment 1 | 10

Disease

Carcinoma 45 | 11,493
Multiple Sclerosis 41 | 540
Eaton-Lambert syndrome 40 | 40
ependymoma 27 | 4,679
medulloblastoma, large-cell 26 | 6,241
glioblastoma 24 | 5,792
atypical teratoid / rhabdoid tumor 23 | 5,112
Kidney cancer 22 | 2,613
adult high grade glioma 22 | 3,801
Astrocytoma, Pilocytic 20 | 3,081
primitive neuroectodermal tumor 19 | 3,035
group 3 medulloblastoma 17 | 4,104
osteosarcoma 16 | 7,950
malignant mesothelioma 15 | 3,232
oligodendroglioma 15 | 2,850
psoriasis 15 | 6,694
astrocytic glioma 14 | 2,597
lung cancer 14 | 4,740
ovarian cancer 14 | 8,520
Epilepsy 13 | 792
Long QT syndrome 13 | 39
lung carcinoma 11 | 2,843
pituitary cancer 10 | 1,972
Atrial Fibrillation 9 | 124
cystic fibrosis 9 | 1,696
Breast cancer 8 | 3,578
Schizophrenia 8 | 1,160
subependymal giant cell astrocytoma 8 | 2,287
Bipolar Disorder 7 | 666
Brugada syndrome 7 | 29
Melanoma 7 | 711
Skin cancer 7 | 469
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
Intellectual disability 6 | 1,016
Liver cancer 6 | 604
colon cancer 6 | 1,478
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
Acquired metabolic disease 5 | 336
Cardiac arrest 5 | 36
Episodic ataxia 5 | 22
Heart disease 5 | 306
Muscle hypotonia 5 | 571
Myoclonus 5 | 74
Pick disease 5 | 1,894
Seizures 5 | 596
Ventricular Fibrillation 5 | 17
adrenocortical carcinoma 5 | 1,428
interstitial cystitis 5 | 2,312
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 4 | 21
Amyotrophic lateral sclerosis 4 | 451
Atrioventricular block 4 | 35
Cardiomyopathy 4 | 116
Catecholaminergic polymorphic ventricular tachycardia 4 | 12
Cerebellar Ataxia 4 | 304
Familial atrial fibrillation 4 | 23
Heart conduction disease 4 | 83
Infantile onset 4 | 238
Partial Epilepsy Treatment Adjunct 4 | 16
Prolonged QT interval 4 | 15
Romano-Ward Syndrome 4 | 12
Short QT syndrome 4 | 12
Sudden Cardiac Death 4 | 29
Syncope 4 | 22
Timothy syndrome 4 | 11
Torsades de Pointes 4 | 8
Type 2 diabetes mellitus 4 | 272
active Crohn's disease 4 | 922
lung adenocarcinoma 4 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
progressive supranuclear palsy 4 | 676
Autosomal recessive predisposition 3 | 1,442
Cardiac Arrhythmia 3 | 103
Chronic obstructive pulmonary disease 3 | 184
Cognitive delay 3 | 608
Diaphragmatic Hernia 3 | 40
Dysarthria 3 | 192
Epileptic encephalopathy 3 | 26
Global developmental delay 3 | 608
Hearing Loss, Noise-Induced 3 | 5
Hepatomegaly 3 | 285
Long QT syndrome 1 3 | 20
Mental and motor retardation 3 | 608
Neurodegenerative disease 3 | 414
Noise-induced hearing loss 3 | 5
Osteoporosis 3 | 363
Palpitations 3 | 18
Sensorineural hearing loss 3 | 106
Spinocerebellar ataxia type 13 3 | 5
Tonic - clonic seizures 3 | 44
Tremor 3 | 113
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
invasive ductal carcinoma 3 | 2,951
medulloblastoma 3 | 720
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819

Tissue

Endocrine System 51 | 18,159
Female tissues 48 | 17,400
Nervous System 48 | 16,725
Digestive Tract 47 | 17,369
Male tissues 47 | 17,142
Skin and soft tissues 45 | 17,230
Liver and Pancreas 44 | 16,750
Urinary Tract 43 | 16,678
Blood and immune system 40 | 16,909
Respiratory system 39 | 16,393
Cardiovascular System 33 | 15,192

Target Family

Ion Channel 52 | 344

DTO Protein Class (1)

Potassium channel family 52 | 52
Class A rhodopsin like 749 | 749
Protein kinase 535 | 535
Non-protein kinase 67 | 67
Neurotransmitter receptor, cys... 47 | 47
Adhesion class 33 | 33
Transient receptor potential c... 24 | 24
Class C metabotropic glutamate... 23 | 23
Glutamate-gated ion channel (... 19 | 19
Class B secretin like 16 | 16
Inward rectifier-type potassiu... 16 | 16
Two pore domain potassium chan... 15 | 15
Calcium channel alpha-1 subuni... 13 | 13
Class F frizzled-type 12 | 12
Cyclic nucleotide-gated cation... 10 | 10
Sodium channel family 10 | 10
Amiloride-sensitive sodium cha... 9 | 9
Chloride channel family 9 | 9
Calcium channel auxiliary subu... 8 | 8
3-ketosteroid receptors 7 | 7
Atp-gated p2x receptor cation ... 7 | 7
Intracellular chloride channel... 6 | 6
Polycystin cation channel (pcc... 6 | 6
Ryanodine-inositol 1,4,5-triph... 6 | 6
Transmembrane channel (TMC) fa... 6 | 6
Calcium-dependent chloride cha... 5 | 5
Fxyd family 5 | 5
Anion channel-forming bestroph... 4 | 4
Calcium channel auxiliary subu... 4 | 4
Calcium channel auxiliary subu... 4 | 4
Calcium homeostasis modulator ... 4 | 4
Calcium-activated potassium ch... 4 | 4
Cation channel sperm-associate... 4 | 4
Epithelial chloride channel (e... 4 | 4
Other 7TM proteins 4 | 4
Sodium channel auxiliary subun... 4 | 4
Vitamin d receptor-like recept... 4 | 4
Anion channel tweety (tweety) ... 3 | 3
Coup-tf-like receptors 3 | 3
Estrogen-related receptors 3 | 3
Gap junction-forming innexin (... 3 | 3
Liver x receptor-like receptor... 3 | 3
Nerve growth factor ib-like re... 3 | 3
Peroxisome proliferator-activa... 3 | 3
Phagocyte (gp91(phox)) nadph o... 3 | 3
Retinoic acid receptors 3 | 3
Retinoic acid-related orphans 3 | 3
Retinoid x receptors 3 | 3
Voltage-gated potassium channe... 3 | 3
Dax-like receptors 2 | 2
Estrogen receptors 2 | 2
FAM26 family 2 | 2
Fushi tarazu f1-like receptors 2 | 2
Golgi pH regulator family 2 | 2
Hepatocyte nuclear factor-4 re... 2 | 2
Mechanical nociceptor, piezo (... 2 | 2
Phospholemman (plm) family 2 | 2
Rev-erb receptors 2 | 2
SLC26A-SulP transporter family 2 | 2
Tailless-like receptors 2 | 2
Testicular receptors 2 | 2
Thyroid hormone receptors 2 | 2
Tmem38 family 2 | 2
Unclassified protein 2 | 2
ABCC family 1 | 1
Calcium release-activated calc... 1 | 1
Cation-nonselective channel fa... 1 | 1
Germ cell nuclear factor recep... 1 | 1
Intracellular chloride channel... 1 | 1
MCU family 1 | 1
Membrane protein mlc1 family 1 | 1
PMP-22-EMP-MP20 family 1 | 1
The phagocyte (gp91(phox)) nad... 1 | 1
Voltage-gated proton channel (... 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily H member 3 KCNH3 Tclin Ion Channel -1.07866 11.8 67
Potassium voltage-gated channel subfamily A member 7 KCNA7 Tclin Ion Channel -0.87978 7.43 59
Potassium voltage-gated channel subfamily E member 3 KCNE3 Tbio Ion Channel -1.63683 41.4 75
Potassium voltage-gated channel subfamily D member 3 KCND3 Tclin Ion Channel -2.34610 217.9 162
Potassium voltage-gated channel subfamily E member 4 KCNE4 Tbio Ion Channel -1.17671 15.9 99
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
Potassium voltage-gated channel subfamily B member 1 KCNB1 Tclin Ion Channel -2.57484 386.0 303
Potassium voltage-gated channel subfamily G member 1 KCNG1 Tclin Ion Channel -1.83662 59.3 87
Potassium voltage-gated channel subfamily G member 2 KCNG2 Tclin Ion Channel -0.41945 2.53 93
Potassium channel subfamily U member 1 KCNU1 Tbio Ion Channel -1.65772 43.3 45