Development Level

Tclin 8 | 613
Tchem 6 | 1,598
Tbio 1 | 11,445
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

decreased bone mineral content 2 | 151
decreased lean body mass 2 | 135
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal sleep behavior 1 | 70
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased vertical activity 1 | 208
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thrombocytopenia 1 | 56

Disease

Carcinoma 14 | 11,493
ependymoma 6 | 4,679
ovarian cancer 6 | 8,520
medulloblastoma, large-cell 5 | 6,241
psoriasis 5 | 6,694
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
lung cancer 4 | 4,740
oligodendroglioma 4 | 2,850
osteosarcoma 4 | 7,950
primitive neuroectodermal tumor 4 | 3,035
Bipolar Disorder 3 | 666
Depressive disorder 3 | 409
Hypertension 3 | 396
Mental Depression 3 | 333
Obesity 3 | 678
Osteoporosis 3 | 363
Postmenopausal osteoporosis 3 | 19
astrocytic glioma 3 | 2,597
diabetes mellitus 3 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
post-traumatic stress disorder 3 | 40
Anhedonia 2 | 27
Anorexia 2 | 43
Anxiety Disorders 2 | 38
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Cocaine-Related Disorders 2 | 92
Glucocorticoid Induced Osteoporosis 2 | 4
Holoprosencephaly 3 2 | 7
Hypercalcemia 2 | 59
Hyperglycemia 2 | 137
Hypertensive disease 2 | 292
Hypoglycemia 2 | 152
Hypogonadal Osteoporosis in Males 2 | 4
Irritable bowel syndrome 2 | 60
Kidney cancer 2 | 2,613
Lung diseases 2 | 50
Mood Disorders 2 | 184
Panic disorder 2 | 61
Schizophrenia 2 | 1,160
Short stature 2 | 531
Type 2 Diabetes Mellitus Treatment Adjunct 2 | 7
Type 2 diabetes mellitus 2 | 272
chronic kidney disease 2 | 90
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Acquired cubitus valgus 1 | 18
Ankylosis 1 | 28
Basal ganglia calcification 1 | 27
Choanal Atresia 1 | 42
Choanal stenosis 1 | 11
Delayed epiphyseal ossification 1 | 10
Delayed maturation of end part of long bone 1 | 10
Depressive Disorder, Major 1 | 19
Diffuse, symmetrical osteosclerosis 1 | 5
Dysentery 1 | 10
Exostosis 1 | 15
Flexion contracture of hip 1 | 10
Hypercalcemia Treatment Adjunct 1 | 1
Hyperphosphaturia 1 | 21
Hypopituitarism 1 | 40
Increased bone density in skeletal bones 1 | 5
Insulinoma 1 | 24
Invasive aspergillosis 1 | 6
Isolated somatotropin deficiency 1 | 30
Lethal skeletal dysplasia 1 | 6
Maffucci syndrome 1 | 6
Mesomelia 1 | 8
Metaphyseal irregularity 1 | 23
Multiple, subcutaneous nodules 1 | 53
Narrow pelvis 1 | 6
Neoplasms 1 | 63
Ollier disease 1 | 18
Osteosclerosis 1 | 31
Pituitary dwarfism 1 | 6
Pituitary hypoplasia 1 | 23
Platyspondyly 1 | 56
Sacral agenesis 1 | 3
Septooptic dysplasia 1 | 19
Shigellosis 1 | 21
Short bowel syndrome 1 | 16
Short hands 1 | 50
Short phalanx of finger 1 | 32
Short tubular bones 1 | 22
Splayed metaphyses 1 | 19
Subcutaneous nodule 1 | 53
Substance abuse 1 | 59
Urine phosphorous concentration above normal 1 | 21

Tissue

Endocrine System 16 | 18,159
Urinary Tract 16 | 16,678
Digestive Tract 15 | 17,369
Liver and Pancreas 15 | 16,750
Skin and soft tissues 15 | 17,230
Female tissues 14 | 17,400
Nervous System 14 | 16,725
Cardiovascular System 13 | 15,192
Male tissues 13 | 17,142
Respiratory system 13 | 16,393
Blood and immune system 12 | 16,909

Target Family

GPCR 16 | 408

DTO Protein Class (1)

Class B secretin like 16 | 16
Class A rhodopsin like 749 | 749
Protein kinase 535 | 535
Non-protein kinase 67 | 67
Potassium channel family 52 | 52
Neurotransmitter receptor, cys... 47 | 47
Adhesion class 33 | 33
Transient receptor potential c... 24 | 24
Class C metabotropic glutamate... 23 | 23
Glutamate-gated ion channel (... 19 | 19
Inward rectifier-type potassiu... 16 | 16
Two pore domain potassium chan... 15 | 15
Calcium channel alpha-1 subuni... 13 | 13
Class F frizzled-type 12 | 12
Cyclic nucleotide-gated cation... 10 | 10
Sodium channel family 10 | 10
Amiloride-sensitive sodium cha... 9 | 9
Chloride channel family 9 | 9
Calcium channel auxiliary subu... 8 | 8
3-ketosteroid receptors 7 | 7
Atp-gated p2x receptor cation ... 7 | 7
Intracellular chloride channel... 6 | 6
Polycystin cation channel (pcc... 6 | 6
Ryanodine-inositol 1,4,5-triph... 6 | 6
Transmembrane channel (TMC) fa... 6 | 6
Calcium-dependent chloride cha... 5 | 5
Fxyd family 5 | 5
Anion channel-forming bestroph... 4 | 4
Calcium channel auxiliary subu... 4 | 4
Calcium channel auxiliary subu... 4 | 4
Calcium homeostasis modulator ... 4 | 4
Calcium-activated potassium ch... 4 | 4
Cation channel sperm-associate... 4 | 4
Epithelial chloride channel (e... 4 | 4
Other 7TM proteins 4 | 4
Sodium channel auxiliary subun... 4 | 4
Vitamin d receptor-like recept... 4 | 4
Anion channel tweety (tweety) ... 3 | 3
Coup-tf-like receptors 3 | 3
Estrogen-related receptors 3 | 3
Gap junction-forming innexin (... 3 | 3
Liver x receptor-like receptor... 3 | 3
Nerve growth factor ib-like re... 3 | 3
Peroxisome proliferator-activa... 3 | 3
Phagocyte (gp91(phox)) nadph o... 3 | 3
Retinoic acid receptors 3 | 3
Retinoic acid-related orphans 3 | 3
Retinoid x receptors 3 | 3
Voltage-gated potassium channe... 3 | 3
Dax-like receptors 2 | 2
Estrogen receptors 2 | 2
FAM26 family 2 | 2
Fushi tarazu f1-like receptors 2 | 2
Golgi pH regulator family 2 | 2
Hepatocyte nuclear factor-4 re... 2 | 2
Mechanical nociceptor, piezo (... 2 | 2
Phospholemman (plm) family 2 | 2
Rev-erb receptors 2 | 2
SLC26A-SulP transporter family 2 | 2
Tailless-like receptors 2 | 2
Testicular receptors 2 | 2
Thyroid hormone receptors 2 | 2
Tmem38 family 2 | 2
Unclassified protein 2 | 2
ABCC family 1 | 1
Calcium release-activated calc... 1 | 1
Cation-nonselective channel fa... 1 | 1
Germ cell nuclear factor recep... 1 | 1
Intracellular chloride channel... 1 | 1
MCU family 1 | 1
Membrane protein mlc1 family 1 | 1
PMP-22-EMP-MP20 family 1 | 1
The phagocyte (gp91(phox)) nad... 1 | 1
Voltage-gated proton channel (... 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G-protein coupled receptor 157 GPR157 Tdark GPCR -0.04139 1.14 111
Secretin receptor SCTR Tclin GPCR -1.58176 34.8 193
Glucagon-like peptide 1 receptor GLP1R Tclin GPCR -2.92059 820.5 306
Growth hormone-releasing hormone receptor GHRHR Tclin GPCR -2.10486 138.0 205
Glucagon-like peptide 2 receptor GLP2R Tclin GPCR -1.45855 24.5 221
Vasoactive intestinal polypeptide receptor 2 VIPR2 Tchem GPCR -2.20668 142.1 255
Pituitary adenylate cyclase-activating polypeptide type I receptor ADCYAP1R1 Tchem GPCR -1.98111 94.8 184
Calcitonin receptor CALCR Tclin GPCR -2.61142 364.5 0
Parathyroid hormone 2 receptor PTH2R Tchem GPCR -1.44424 28.0 123
Gastric inhibitory polypeptide receptor GIPR Tchem GPCR -1.81625 78.7 347