Development Level

Tdark 448 | 6,588
Tchem 127 | 1,598
Tbio 90 | 11,445
Tclin 84 | 613

Collection

GPCR: IDG Consortium (Targets) 98 | 126
GPCR: IDG Consortium (Complete... 19 | 25

IMPC Phenotype

decreased vertical activity 9 | 208
abnormal behavior 8 | 298
enlarged heart 7 | 210
hyperactivity 6 | 148
abnormal heart morphology 5 | 162
decreased total body fat amoun... 5 | 207
preweaning lethality, incomple... 5 | 499
abnormal kidney morphology 4 | 65
abnormal seminal vesicle morph... 4 | 114
increased circulating sodium l... 4 | 71
preweaning lethality, complete... 4 | 979
abnormal skin coloration 3 | 25
abnormal skin morphology 3 | 50
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
improved glucose tolerance 3 | 79
increased fasted circulating g... 3 | 76
increased lean body mass 3 | 172
increased mean corpuscular vol... 3 | 92
increased total body fat amoun... 3 | 134
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
decreased body weight 2 | 161
decreased caudal vertebrae num... 2 | 53
decreased circulating alanine ... 2 | 47
decreased circulating insulin ... 2 | 76
decreased eosinophil cell numb... 2 | 24
decreased grip strength 2 | 116
decreased heart weight 2 | 27
decreased lean body mass 2 | 135
decreased startle reflex 2 | 75
female infertility 2 | 60
hypoactivity 2 | 132
increased circulating calcium ... 2 | 34
increased circulating creatini... 2 | 38
increased erythrocyte cell num... 2 | 39
increased hemoglobin content 2 | 45
male infertility 2 | 123
polycystic kidney 2 | 15
abnormal coat-hair pigmentatio... 1 | 64
abnormal colon morphology 1 | 3
abnormal liver morphology 1 | 17
abnormal lymph node morphology 1 | 3
abnormal retinal blood vessel ... 1 | 26
abnormal sleep behavior 1 | 70
abnormal tail length 1 | 3
abnormal testis morphology 1 | 43
absent pinna reflex 1 | 23
absent startle reflex 1 | 24
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased IgE level 1 | 6
decreased T cell number 1 | 15
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 51
decreased brain size 1 | 4
decreased circulating LDL chol... 1 | 38
decreased circulating creatini... 1 | 39
decreased fasted circulating g... 1 | 65
decreased heart rate 1 | 18
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
decreased total retina thickne... 1 | 17
decreased urine magnesium leve... 1 | 3
edema 1 | 59
enlarged epididymis 1 | 31
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating lipase l... 1 | 3
increased circulating magnesiu... 1 | 10
increased circulating total pr... 1 | 28
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased vertical activity 1 | 24
prolonged RR interval 1 | 8
scaly skin 1 | 4
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small superior vagus ganglion 1 | 74
small testis 1 | 58
small thymus 1 | 16
thick skin 1 | 4
urinary bladder obstruction 1 | 4
vertebral transformation 1 | 12

Disease

Carcinoma 556 | 11,493
psoriasis 128 | 6,694
osteosarcoma 120 | 7,950
diabetes mellitus 110 | 1,728
medulloblastoma, large-cell 102 | 6,241
ovarian cancer 96 | 8,520
lung cancer 72 | 4,740
glioblastoma 69 | 5,792
adult high grade glioma 67 | 3,801
Schizophrenia 63 | 1,160
atypical teratoid / rhabdoid tumor 63 | 5,112
ependymoma 60 | 4,679
interstitial cystitis 59 | 2,312
Astrocytoma, Pilocytic 57 | 3,081
lung carcinoma 52 | 2,843
lung adenocarcinoma 48 | 2,716
invasive ductal carcinoma 47 | 2,951
group 3 medulloblastoma 45 | 4,104
Cancer 43 | 2,499
Bipolar Disorder 42 | 666
malignant mesothelioma 42 | 3,232
primitive neuroectodermal tumor 42 | 3,035
oligodendroglioma 41 | 2,850
Obesity 39 | 678
Depressive disorder 38 | 409
non-small cell lung cancer 38 | 2,890
tuberculosis 37 | 2,010
ulcerative colitis 37 | 1,819
Breast cancer 35 | 3,578
Kidney cancer 35 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 35 | 2,989
Asthma 34 | 385
astrocytic glioma 33 | 2,597
ductal carcinoma in situ 32 | 1,745
Alcoholic Intoxication, Chronic 31 | 289
intraductal papillary-mucinous adenoma (IPMA) 30 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,291
Mood Disorders 29 | 184
pancreatic cancer 29 | 2,398
pituitary cancer 29 | 1,972
Mental Depression 27 | 333
breast carcinoma 27 | 1,638
Major Depressive Disorder 26 | 301
Multiple Sclerosis 26 | 540
colon cancer 26 | 1,478
cutaneous lupus erythematosus 26 | 1,057
Parkinson's disease 24 | 392
adrenocortical carcinoma 24 | 1,428
primary Sjogren syndrome 24 | 735
Allergic rhinitis 23 | 94
Migraine 20 | 83
Rheumatoid arthritis 20 | 1,191
cystic fibrosis 20 | 1,696
group 4 medulloblastoma 20 | 1,855
Common cold 19 | 67
Hypertension 19 | 396
Nasal congestion 18 | 21
Nasal discharge 18 | 24
mucosa-associated lymphoid tissue lymphoma 18 | 484
subependymal giant cell astrocytoma 18 | 2,287
Epilepsy 17 | 792
Pain 17 | 103
Pain agnosia 17 | 104
Alcohol dependence 16 | 107
Attention deficit hyperactivity disorder 16 | 278
Unipolar Depression 16 | 250
astrocytoma 16 | 1,146
Atopic dermatitis 15 | 952
Substance Withdrawal Syndrome 15 | 55
Cocaine-Related Disorders 14 | 92
Pick disease 14 | 1,894
Seizures 14 | 596
hepatocellular carcinoma 14 | 547
Asthma management 13 | 19
Autistic Disorder 13 | 364
Autosomal recessive predisposition 13 | 1,442
Bronchitis 13 | 43
Cerebrovascular disease 13 | 238
Hemolytic anemia 13 | 77
Pulmonary emphysema 13 | 48
Status Epilepticus 13 | 98
Acute exacerbation of asthma 12 | 14
Alzheimer's disease 12 | 658
Atherosclerosis 12 | 291
Endometriosis 12 | 540
Hyperalgesia 12 | 83
Hypertensive disorder 12 | 56
Hypotension 12 | 82
Liver Cirrhosis, Experimental 12 | 769
Melanoma 12 | 711
Opiate dependence 12 | 29
pancreatic carcinoma 12 | 562
primary pancreatic ductal adenocarcinoma 12 | 1,109
Acquired metabolic disease 11 | 336
Acromegaly 11 | 51
Hypertensive disease 11 | 292
Vascular disease 11 | 319
gastric carcinoma 11 | 807
head and neck cancer 11 | 271
medulloblastoma 11 | 720

Tissue

Endocrine System 393 | 18,159
Female tissues 306 | 17,400
Nervous System 287 | 16,725
Male tissues 284 | 17,142
Digestive Tract 283 | 17,369
Blood and immune system 282 | 16,909
Skin and soft tissues 272 | 17,230
Urinary Tract 249 | 16,678
Liver and Pancreas 247 | 16,750
Respiratory system 234 | 16,393
Cardiovascular System 204 | 15,192

Target Family

oGPCR 421 | 421
GPCR 320 | 408
Non-IDG 5 | 12,091
Enzyme 3 | 4,145

DTO Protein Class (1)

Class A rhodopsin like 749 | 749
Protein kinase 535 | 535
Non-protein kinase 67 | 67
Potassium channel family 52 | 52
Neurotransmitter receptor, cys... 47 | 47
Adhesion class 33 | 33
Transient receptor potential c... 24 | 24
Class C metabotropic glutamate... 23 | 23
Glutamate-gated ion channel (... 19 | 19
Class B secretin like 16 | 16
Inward rectifier-type potassiu... 16 | 16
Two pore domain potassium chan... 15 | 15
Calcium channel alpha-1 subuni... 13 | 13
Class F frizzled-type 12 | 12
Cyclic nucleotide-gated cation... 10 | 10
Sodium channel family 10 | 10
Amiloride-sensitive sodium cha... 9 | 9
Chloride channel family 9 | 9
Calcium channel auxiliary subu... 8 | 8
3-ketosteroid receptors 7 | 7
Atp-gated p2x receptor cation ... 7 | 7
Intracellular chloride channel... 6 | 6
Polycystin cation channel (pcc... 6 | 6
Ryanodine-inositol 1,4,5-triph... 6 | 6
Transmembrane channel (TMC) fa... 6 | 6
Calcium-dependent chloride cha... 5 | 5
Fxyd family 5 | 5
Anion channel-forming bestroph... 4 | 4
Calcium channel auxiliary subu... 4 | 4
Calcium channel auxiliary subu... 4 | 4
Calcium homeostasis modulator ... 4 | 4
Calcium-activated potassium ch... 4 | 4
Cation channel sperm-associate... 4 | 4
Epithelial chloride channel (e... 4 | 4
Other 7TM proteins 4 | 4
Sodium channel auxiliary subun... 4 | 4
Vitamin d receptor-like recept... 4 | 4
Anion channel tweety (tweety) ... 3 | 3
Coup-tf-like receptors 3 | 3
Estrogen-related receptors 3 | 3
Gap junction-forming innexin (... 3 | 3
Liver x receptor-like receptor... 3 | 3
Nerve growth factor ib-like re... 3 | 3
Peroxisome proliferator-activa... 3 | 3
Phagocyte (gp91(phox)) nadph o... 3 | 3
Retinoic acid receptors 3 | 3
Retinoic acid-related orphans 3 | 3
Retinoid x receptors 3 | 3
Voltage-gated potassium channe... 3 | 3
Dax-like receptors 2 | 2
Estrogen receptors 2 | 2
FAM26 family 2 | 2
Fushi tarazu f1-like receptors 2 | 2
Golgi pH regulator family 2 | 2
Hepatocyte nuclear factor-4 re... 2 | 2
Mechanical nociceptor, piezo (... 2 | 2
Phospholemman (plm) family 2 | 2
Rev-erb receptors 2 | 2
SLC26A-SulP transporter family 2 | 2
Tailless-like receptors 2 | 2
Testicular receptors 2 | 2
Thyroid hormone receptors 2 | 2
Tmem38 family 2 | 2
Unclassified protein 2 | 2
ABCC family 1 | 1
Calcium release-activated calc... 1 | 1
Cation-nonselective channel fa... 1 | 1
Germ cell nuclear factor recep... 1 | 1
Intracellular chloride channel... 1 | 1
MCU family 1 | 1
Membrane protein mlc1 family 1 | 1
PMP-22-EMP-MP20 family 1 | 1
The phagocyte (gp91(phox)) nad... 1 | 1
Voltage-gated proton channel (... 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Urotensin-2 receptor UTS2R Tchem GPCR -1.95094 62.5 182
Olfactory receptor 5H15 OR5H15 Tdark oGPCR 0.00000 35
Olfactory receptor 4F4 OR4F4 Tdark oGPCR 0.00000 45
Olfactory receptor 4C12 OR4C12 Tdark oGPCR 0.31 0.30 74
Olfactory receptor 4K3 OR4K3 Tdark oGPCR 0.00000 0
Adrenocorticotropic hormone receptor MC2R Tclin GPCR -2.22640 172.4 223
Olfactory receptor 6C68 OR6C68 Tdark oGPCR 0.00000 49
Olfactory receptor 2M4 OR2M4 Tdark oGPCR 0.95 0.18 19
Olfactory receptor 2M2 OR2M2 Tdark oGPCR 0.00000 61
Olfactory receptor 2V2 OR2V2 Tdark oGPCR 0.00000 58