Development Level

Tbio 3 | 11,445
Tchem 3 | 1,598
Tclin 3 | 613

Collection

Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

decreased vertical activity 2 | 208
abnormal pelvic girdle bone mo... 1 | 12
hydrometra 1 | 53
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74

Disease

Carcinoma 8 | 11,493
Edema 5 | 81
Hypertensive disorder 5 | 56
Hypokalemia Prevention 5 | 6
Liddle syndrome 5 | 14
Pseudohypoaldosteronism 4 | 23
cystic fibrosis 4 | 1,696
Autosomal recessive predisposition 3 | 1,442
Brain Ischemia 3 | 110
Bronchiectasis 3 | 64
Bronchitis, Chronic 3 | 12
Dehydration 3 | 40
Diarrhea 3 | 253
Failure to gain weight 3 | 365
Feeding difficulties in infancy 3 | 175
Hyperactive renin-angiotensin system 3 | 8
Hyperaldosteronism 3 | 35
Hyperkalemia 3 | 17
Hypertension 3 | 396
Hypertensive disease 3 | 292
Hyponatremia 3 | 25
Hypotension 3 | 82
Idiopathic bronchiectasis 3 | 4
Increased plasma renin activity 3 | 8
Infantile onset 3 | 238
Inflammation 3 | 120
Kidney disease 3 | 430
Metabolic acidosis 3 | 90
Pediatric failure to thrive 3 | 365
Peripheral Edema due to Chronic Heart Failure 3 | 10
Pseudohypoaldosteronism, Type I, Autosomal Recessive 3 | 3
Pulmonary Edema due to Chronic Heart Failure 3 | 6
Recurrent respiratory infections 3 | 141
Renal salt wasting 3 | 18
Vomiting 3 | 116
autosomal recessive pseudohypoaldosteronism type 1 3 | 3
interstitial cystitis 3 | 2,312
oligodendroglioma 3 | 2,850
psoriasis 3 | 6,694
Astrocytoma, Pilocytic 2 | 3,081
Cardiac Arrhythmia 2 | 103
Cardiac conduction abnormalities 2 | 78
Cerebral Ischemia 2 | 37
Conduction disorder of the heart 2 | 79
Constipation 2 | 181
Decreased plasma renin activity 2 | 9
Dyschezia 2 | 135
EKG abnormalities 2 | 78
Electrocardiogram abnormal 2 | 81
Electrocardiogram change 2 | 78
Fatigue 2 | 182
Hydrarthrosis 2 | 4
Hypoaldosteronism 2 | 12
Hypokalemia 2 | 52
Hypokalemic alkalosis 2 | 4
Increase in blood pressure 2 | 119
Kidney Diseases 2 | 114
Kidney Failure 2 | 111
Kidney damage 2 | 25
Lung diseases 2 | 50
Mineralocorticoid insufficiency 2 | 12
Muscle Weakness 2 | 170
Renal Insufficiency 2 | 90
Renal failure in adulthood 2 | 76
Vascular disease 2 | 319
adult high grade glioma 2 | 3,801
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
Alcohol dependence 1 | 107
Angelman syndrome 1 | 34
Autistic Disorder 1 | 364
Cardiovascular system disease 1 | 246
Endometriosis 1 | 540
Hypothyroidism 1 | 122
Kidney cancer 1 | 2,613
Lung disease 1 | 142
Neoplasms, Germ Cell and Embryonal 1 | 15
Polycystic ovary syndrome 1 | 360
Prader-Willi syndrome 1 | 48
Pre-Eclampsia 1 | 68
Proteinuria 1 | 144
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
esophageal adenocarcinoma 1 | 737
gastric carcinoma 1 | 807
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
nephrosclerosis 1 | 333
ovarian cancer 1 | 8,520
pancreatic cancer 1 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pituitary cancer 1 | 1,972
spina bifida 1 | 1,074
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Nervous System 9 | 16,725
Skin and soft tissues 9 | 17,230
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Male tissues 8 | 17,142
Respiratory system 8 | 16,393
Urinary Tract 8 | 16,678
Blood and immune system 7 | 16,909
Liver and Pancreas 7 | 16,750
Cardiovascular System 5 | 15,192

Target Family

Ion Channel 9 | 344

DTO Protein Class (1)

Amiloride-sensitive sodium cha... 9 | 9
Class A rhodopsin like 749 | 749
Protein kinase 535 | 535
Non-protein kinase 67 | 67
Potassium channel family 52 | 52
Neurotransmitter receptor, cys... 47 | 47
Adhesion class 33 | 33
Transient receptor potential c... 24 | 24
Class C metabotropic glutamate... 23 | 23
Glutamate-gated ion channel (... 19 | 19
Class B secretin like 16 | 16
Inward rectifier-type potassiu... 16 | 16
Two pore domain potassium chan... 15 | 15
Calcium channel alpha-1 subuni... 13 | 13
Class F frizzled-type 12 | 12
Cyclic nucleotide-gated cation... 10 | 10
Sodium channel family 10 | 10
Chloride channel family 9 | 9
Calcium channel auxiliary subu... 8 | 8
3-ketosteroid receptors 7 | 7
Atp-gated p2x receptor cation ... 7 | 7
Intracellular chloride channel... 6 | 6
Polycystin cation channel (pcc... 6 | 6
Ryanodine-inositol 1,4,5-triph... 6 | 6
Transmembrane channel (TMC) fa... 6 | 6
Calcium-dependent chloride cha... 5 | 5
Fxyd family 5 | 5
Anion channel-forming bestroph... 4 | 4
Calcium channel auxiliary subu... 4 | 4
Calcium channel auxiliary subu... 4 | 4
Calcium homeostasis modulator ... 4 | 4
Calcium-activated potassium ch... 4 | 4
Cation channel sperm-associate... 4 | 4
Epithelial chloride channel (e... 4 | 4
Other 7TM proteins 4 | 4
Sodium channel auxiliary subun... 4 | 4
Vitamin d receptor-like recept... 4 | 4
Anion channel tweety (tweety) ... 3 | 3
Coup-tf-like receptors 3 | 3
Estrogen-related receptors 3 | 3
Gap junction-forming innexin (... 3 | 3
Liver x receptor-like receptor... 3 | 3
Nerve growth factor ib-like re... 3 | 3
Peroxisome proliferator-activa... 3 | 3
Phagocyte (gp91(phox)) nadph o... 3 | 3
Retinoic acid receptors 3 | 3
Retinoic acid-related orphans 3 | 3
Retinoid x receptors 3 | 3
Voltage-gated potassium channe... 3 | 3
Dax-like receptors 2 | 2
Estrogen receptors 2 | 2
FAM26 family 2 | 2
Fushi tarazu f1-like receptors 2 | 2
Golgi pH regulator family 2 | 2
Hepatocyte nuclear factor-4 re... 2 | 2
Mechanical nociceptor, piezo (... 2 | 2
Phospholemman (plm) family 2 | 2
Rev-erb receptors 2 | 2
SLC26A-SulP transporter family 2 | 2
Tailless-like receptors 2 | 2
Testicular receptors 2 | 2
Thyroid hormone receptors 2 | 2
Tmem38 family 2 | 2
Unclassified protein 2 | 2
ABCC family 1 | 1
Calcium release-activated calc... 1 | 1
Cation-nonselective channel fa... 1 | 1
Germ cell nuclear factor recep... 1 | 1
Intracellular chloride channel... 1 | 1
MCU family 1 | 1
Membrane protein mlc1 family 1 | 1
PMP-22-EMP-MP20 family 1 | 1
The phagocyte (gp91(phox)) nad... 1 | 1
Voltage-gated proton channel (... 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acid-sensing ion channel 5 ASIC5 Tbio Ion Channel -0.41218 3.22 86
Acid-sensing ion channel 3 ASIC3 Tchem Ion Channel -2.28745 195.8 130
Acid-sensing ion channel 2 ASIC2 Tchem Ion Channel -2.49683 295.8 140
Amiloride-sensitive sodium channel subunit alpha SCNN1A Tclin Ion Channel -1.84273 63.2 184
Amiloride-sensitive sodium channel subunit beta SCNN1B Tclin Ion Channel -1.75374 52.6 316
Amiloride-sensitive sodium channel subunit gamma SCNN1G Tclin Ion Channel -2.10269 131.1 212
Amiloride-sensitive sodium channel subunit delta SCNN1D Tbio Ion Channel -1.16212 14.7 196
Acid-sensing ion channel 1 ASIC1 Tchem Ion Channel -2.08871 126.2 324
Acid-sensing ion channel 4 ASIC4 Tbio Ion Channel -1.16480 13.1 113