Development Level

Tbio 23 | 11,445
Tdark 9 | 6,588
Tchem 1 | 1,598

Collection

GPCR: IDG Consortium (Targets) 18 | 126
GPCR: IDG Consortium (Complete... 6 | 25

IMPC Phenotype

decreased bone mineral density 2 | 126
decreased leukocyte cell numbe... 2 | 73
decreased prepulse inhibition 2 | 82
decreased vertical activity 2 | 208
increased lean body mass 2 | 172
increased or absent threshold ... 2 | 101
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
absent startle reflex 1 | 24
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
female infertility 1 | 60
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased heart weight 1 | 62
increased total body fat amoun... 1 | 134
increased urine microalbumin l... 1 | 2
mammalian phenotype 1 | 17
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 28 | 11,493
psoriasis 20 | 6,694
Kidney cancer 17 | 2,613
lung adenocarcinoma 14 | 2,716
Breast cancer 13 | 3,578
glioblastoma 13 | 5,792
atypical teratoid / rhabdoid tumor 12 | 5,112
ependymoma 12 | 4,679
lung cancer 12 | 4,740
lung carcinoma 12 | 2,843
medulloblastoma, large-cell 12 | 6,241
interstitial cystitis 11 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
osteosarcoma 10 | 7,950
adult high grade glioma 9 | 3,801
invasive ductal carcinoma 8 | 2,951
non-small cell lung cancer 8 | 2,890
ovarian cancer 8 | 8,520
Liver cancer 7 | 604
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
ductal carcinoma in situ 6 | 1,745
malignant mesothelioma 6 | 3,232
Melanoma 5 | 711
Skin cancer 5 | 469
non-small cell lung carcinoma 5 | 317
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Astrocytoma, Pilocytic 4 | 3,081
Immune system cancer 4 | 140
active Crohn's disease 4 | 922
group 4 medulloblastoma 4 | 1,855
mucosa-associated lymphoid tissue lymphoma 4 | 484
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pediatric high grade glioma 4 | 1,064
Endometrial cancer 3 | 311
Epilepsy 3 | 792
Lymphoid leukemia 3 | 160
Schizophrenia 3 | 1,160
acute myeloid leukemia 3 | 783
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
juvenile dermatomyositis 3 | 1,187
oligodendroglioma 3 | 2,850
Atopic dermatitis 2 | 952
Bladder exstrophy 2 | 32
Common variable immunodeficiency 2 | 101
Dermatophytosis 2 | 11
Gastric ulcer 2 | 33
Male infertility 2 | 206
Multiple Sclerosis 2 | 540
active ulcerative colitis 2 | 764
astrocytoma 2 | 1,146
diabetes mellitus 2 | 1,728
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
medulloblastoma 2 | 720
non primary Sjogren syndrome sicca 2 | 891
primitive neuroectodermal tumor 2 | 3,035
tuberculosis 2 | 2,010
urothelial carcinoma 2 | 318
Acquired metabolic disease 1 | 336
Amyotrophic lateral sclerosis 1 | 451
Autistic Disorder 1 | 364
Babinski Reflex 1 | 100
Blindness 1 | 88
Cannabis dependence 1 | 23
Cardiovascular system disease 1 | 246
Congenital disorder of glycosylation 1 | 54
DOID:2627 1 | 94
Degenerative polyarthritis 1 | 115
FEBRILE CONVULSIONS, FAMILIAL, 4 1 | 1
Febrile seizures, familial, 4 1 | 1
Heart conduction disease 1 | 83
Hyperreflexia 1 | 209
Hypoplasia of the brainstem 1 | 22
Liver Cirrhosis, Experimental 1 | 769
Muscle Hypertonia 1 | 88
Neurodegenerative disease 1 | 414
Nonsyndromic deafness 1 | 142
Osteoarthritis 1 | 184
Osteoporosis 1 | 363
Sensorineural hearing loss 1 | 106
Usher Syndrome, Type II 1 | 5
Usher syndrome 1 | 32
Usher syndrome type 2 1 | 5
Usher syndrome type 2C 1 | 2
Usher syndrome, type 2C 1 | 2
X-linked cerebral adrenoleukodystrophy 1 | 116
adrenocortical adenoma 1 | 131
atypical teratoid/rhabdoid tumor 1 | 357
posterior fossa group A ependymoma 1 | 468

Tissue

Female tissues 32 | 17,400
Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Skin and soft tissues 31 | 17,230
Male tissues 30 | 17,142
Respiratory system 30 | 16,393
Blood and immune system 29 | 16,909
Liver and Pancreas 29 | 16,750
Urinary Tract 28 | 16,678
Nervous System 26 | 16,725
Cardiovascular System 22 | 15,192

Target Family

GPCR 33 | 408

DTO Protein Class (1)

Adhesion class 33 | 33
Class A rhodopsin like 749 | 749
Protein kinase 535 | 535
Non-protein kinase 67 | 67
Potassium channel family 52 | 52
Neurotransmitter receptor, cys... 47 | 47
Transient receptor potential c... 24 | 24
Class C metabotropic glutamate... 23 | 23
Glutamate-gated ion channel (... 19 | 19
Class B secretin like 16 | 16
Inward rectifier-type potassiu... 16 | 16
Two pore domain potassium chan... 15 | 15
Calcium channel alpha-1 subuni... 13 | 13
Class F frizzled-type 12 | 12
Cyclic nucleotide-gated cation... 10 | 10
Sodium channel family 10 | 10
Amiloride-sensitive sodium cha... 9 | 9
Chloride channel family 9 | 9
Calcium channel auxiliary subu... 8 | 8
3-ketosteroid receptors 7 | 7
Atp-gated p2x receptor cation ... 7 | 7
Intracellular chloride channel... 6 | 6
Polycystin cation channel (pcc... 6 | 6
Ryanodine-inositol 1,4,5-triph... 6 | 6
Transmembrane channel (TMC) fa... 6 | 6
Calcium-dependent chloride cha... 5 | 5
Fxyd family 5 | 5
Anion channel-forming bestroph... 4 | 4
Calcium channel auxiliary subu... 4 | 4
Calcium channel auxiliary subu... 4 | 4
Calcium homeostasis modulator ... 4 | 4
Calcium-activated potassium ch... 4 | 4
Cation channel sperm-associate... 4 | 4
Epithelial chloride channel (e... 4 | 4
Other 7TM proteins 4 | 4
Sodium channel auxiliary subun... 4 | 4
Vitamin d receptor-like recept... 4 | 4
Anion channel tweety (tweety) ... 3 | 3
Coup-tf-like receptors 3 | 3
Estrogen-related receptors 3 | 3
Gap junction-forming innexin (... 3 | 3
Liver x receptor-like receptor... 3 | 3
Nerve growth factor ib-like re... 3 | 3
Peroxisome proliferator-activa... 3 | 3
Phagocyte (gp91(phox)) nadph o... 3 | 3
Retinoic acid receptors 3 | 3
Retinoic acid-related orphans 3 | 3
Retinoid x receptors 3 | 3
Voltage-gated potassium channe... 3 | 3
Dax-like receptors 2 | 2
Estrogen receptors 2 | 2
FAM26 family 2 | 2
Fushi tarazu f1-like receptors 2 | 2
Golgi pH regulator family 2 | 2
Hepatocyte nuclear factor-4 re... 2 | 2
Mechanical nociceptor, piezo (... 2 | 2
Phospholemman (plm) family 2 | 2
Rev-erb receptors 2 | 2
SLC26A-SulP transporter family 2 | 2
Tailless-like receptors 2 | 2
Testicular receptors 2 | 2
Thyroid hormone receptors 2 | 2
Tmem38 family 2 | 2
Unclassified protein 2 | 2
ABCC family 1 | 1
Calcium release-activated calc... 1 | 1
Cation-nonselective channel fa... 1 | 1
Germ cell nuclear factor recep... 1 | 1
Intracellular chloride channel... 1 | 1
MCU family 1 | 1
Membrane protein mlc1 family 1 | 1
PMP-22-EMP-MP20 family 1 | 1
The phagocyte (gp91(phox)) nad... 1 | 1
Voltage-gated proton channel (... 1 | 1

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adhesion G-protein coupled receptor G1 ADGRG1 Tbio GPCR -1.94601 100.6 182
Adhesion G protein-coupled receptor G3 ADGRG3 Tchem GPCR -0.68899 5.73 99
G-protein coupled receptor 98 ADGRV1 Tbio GPCR -2.51228 316.6 64
Adhesion G protein-coupled receptor E2 ADGRE2 Tbio GPCR -1.67862 48.2 312
Adhesion G protein-coupled receptor L4 ADGRL4 Tbio GPCR -2.27628 174.3 140
Adhesion G protein-coupled receptor A2 ADGRA2 Tbio GPCR -1.45203 30.0 211
Cadherin EGF LAG seven-pass G-type receptor 2 CELSR2 Tbio GPCR -1.22995 16.7 139
Adhesion G protein-coupled receptor A3 ADGRA3 Tbio GPCR -0.95096 10.7 123
Cadherin EGF LAG seven-pass G-type receptor 1 CELSR1 Tbio GPCR -1.47924 34.4 115
Cadherin EGF LAG seven-pass G-type receptor 3 CELSR3 Tbio GPCR -1.38072 25.3 190