Development Level

Tdark 463 | 6,588
Tchem 143 | 1,598
Tbio 135 | 11,445
Tclin 96 | 613

Collection

GPCR: IDG Consortium (Targets) 126 | 126
GPCR: IDG Consortium (Complete... 25 | 25

IMPC Phenotype

decreased vertical activity 16 | 208
enlarged heart 11 | 210
preweaning lethality, complete... 10 | 979
abnormal behavior 9 | 298
preweaning lethality, incomple... 9 | 499
abnormal heart morphology 8 | 162
hyperactivity 8 | 148
decreased bone mineral content 6 | 151
decreased bone mineral density 6 | 126
decreased total body fat amoun... 6 | 207
increased lean body mass 5 | 172
increased total body fat amoun... 5 | 134
abnormal bone structure 4 | 187
abnormal kidney morphology 4 | 65
abnormal seminal vesicle morph... 4 | 114
decreased lean body mass 4 | 135
decreased startle reflex 4 | 75
improved glucose tolerance 4 | 79
increased circulating sodium l... 4 | 71
abnormal behavioral response t... 3 | 66
abnormal epididymis morphology 3 | 42
abnormal skin coloration 3 | 25
abnormal skin morphology 3 | 50
decreased body weight 3 | 161
decreased heart weight 3 | 27
decreased prepulse inhibition 3 | 82
embryonic lethality prior to t... 3 | 278
female infertility 3 | 60
impaired glucose tolerance 3 | 75
increased circulating creatini... 3 | 38
increased fasted circulating g... 3 | 76
increased hemoglobin content 3 | 45
increased mean corpuscular vol... 3 | 92
increased or absent threshold ... 3 | 101
small superior vagus ganglion 3 | 74
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal liver morphology 2 | 17
abnormal sleep behavior 2 | 70
absent startle reflex 2 | 24
decreased caudal vertebrae num... 2 | 53
decreased circulating alanine ... 2 | 47
decreased circulating creatini... 2 | 39
decreased circulating insulin ... 2 | 76
decreased eosinophil cell numb... 2 | 24
decreased grip strength 2 | 116
decreased hemoglobin content 2 | 68
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 50
embryonic lethality prior to o... 2 | 239
enlarged epididymis 2 | 31
hypoactivity 2 | 132
impaired pupillary reflex 2 | 26
increased bone mineral content 2 | 108
increased circulating calcium ... 2 | 34
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased circulating triglyce... 2 | 42
increased erythrocyte cell num... 2 | 39
increased heart weight 2 | 62
increased mean platelet volume 2 | 45
male infertility 2 | 123
microphthalmia 2 | 26
polycystic kidney 2 | 15
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
short tibia 2 | 97
abnormal embryo turning 1 | 31
abnormal head morphology 1 | 10
abnormal lymph node morphology 1 | 3
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
absent pinna reflex 1 | 23
absent vibrissae 1 | 12
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating serum al... 1 | 82
decreased hematocrit 1 | 46
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased total retina thickne... 1 | 17
edema 1 | 59
enlarged uterus 1 | 11
hydrometra 1 | 53
increased circulating HDL chol... 1 | 80
increased circulating bilirubi... 1 | 16
increased circulating lipase l... 1 | 3
increased circulating magnesiu... 1 | 10
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
limb grasping 1 | 41
prenatal lethality 1 | 28
scaly skin 1 | 4
small kidney 1 | 16
small spleen 1 | 19
small thymus 1 | 16
thick skin 1 | 4
urinary bladder obstruction 1 | 4

Disease

Carcinoma 629 | 11,493
psoriasis 179 | 6,694
osteosarcoma 150 | 7,950
medulloblastoma, large-cell 135 | 6,241
ovarian cancer 123 | 8,520
diabetes mellitus 118 | 1,728
glioblastoma 103 | 5,792
lung cancer 101 | 4,740
atypical teratoid / rhabdoid tumor 98 | 5,112
ependymoma 95 | 4,679
adult high grade glioma 91 | 3,801
interstitial cystitis 78 | 2,312
Schizophrenia 77 | 1,160
lung carcinoma 75 | 2,843
Astrocytoma, Pilocytic 70 | 3,081
Kidney cancer 70 | 2,613
group 3 medulloblastoma 70 | 4,104
lung adenocarcinoma 67 | 2,716
invasive ductal carcinoma 60 | 2,951
Breast cancer 59 | 3,578
primitive neuroectodermal tumor 58 | 3,035
oligodendroglioma 57 | 2,850
malignant mesothelioma 56 | 3,232
non-small cell lung cancer 53 | 2,890
Bipolar Disorder 51 | 666
Cancer 51 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 48 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 48 | 3,291
astrocytic glioma 46 | 2,597
tuberculosis 46 | 2,010
Obesity 45 | 678
intraductal papillary-mucinous adenoma (IPMA) 45 | 2,955
ulcerative colitis 45 | 1,819
Depressive disorder 44 | 409
ductal carcinoma in situ 43 | 1,745
pituitary cancer 42 | 1,972
Alcoholic Intoxication, Chronic 39 | 289
Mood Disorders 36 | 184
breast carcinoma 36 | 1,638
pancreatic cancer 36 | 2,398
Asthma 35 | 385
Mental Depression 33 | 333
colon cancer 33 | 1,478
Major Depressive Disorder 32 | 301
subependymal giant cell astrocytoma 32 | 2,287
cutaneous lupus erythematosus 31 | 1,057
Multiple Sclerosis 29 | 540
adrenocortical carcinoma 29 | 1,428
Parkinson's disease 28 | 392
cystic fibrosis 28 | 1,696
group 4 medulloblastoma 27 | 1,855
Epilepsy 26 | 792
primary Sjogren syndrome 25 | 735
Allergic rhinitis 23 | 94
Rheumatoid arthritis 23 | 1,191
Hypertension 22 | 396
Melanoma 22 | 711
Unipolar Depression 22 | 250
mucosa-associated lymphoid tissue lymphoma 22 | 484
Attention deficit hyperactivity disorder 21 | 278
Migraine 21 | 83
Alcohol dependence 20 | 107
astrocytoma 20 | 1,146
Autistic Disorder 19 | 364
Autosomal recessive predisposition 19 | 1,442
Common cold 19 | 67
Pick disease 19 | 1,894
Cocaine-Related Disorders 18 | 92
Liver cancer 18 | 604
Nasal congestion 18 | 21
Nasal discharge 18 | 24
Pain agnosia 18 | 104
Skin cancer 18 | 469
Atopic dermatitis 17 | 952
Pain 17 | 103
gastric carcinoma 17 | 807
Liver Cirrhosis, Experimental 16 | 769
Seizures 16 | 596
medulloblastoma 16 | 720
Acquired metabolic disease 15 | 336
Status Epilepticus 15 | 98
Substance Withdrawal Syndrome 15 | 55
esophageal adenocarcinoma 15 | 737
non primary Sjogren syndrome sicca 15 | 891
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
primary pancreatic ductal adenocarcinoma 15 | 1,109
Panic disorder 14 | 61
Vascular disease 14 | 319
fibroadenoma 14 | 559
hepatocellular carcinoma 14 | 547
pediatric high grade glioma 14 | 1,064
Alzheimer's disease 13 | 658
Atherosclerosis 13 | 291
Bronchitis 13 | 43
Cerebrovascular disease 13 | 238
Endometriosis 13 | 540
Hemolytic anemia 13 | 77
Hyperalgesia 13 | 83
Hypertensive disease 13 | 292
Pulmonary emphysema 13 | 48

Tissue

Endocrine System 477 | 18,159
Female tissues 388 | 17,400
Digestive Tract 364 | 17,369
Nervous System 363 | 16,725
Male tissues 362 | 17,142
Blood and immune system 355 | 16,909
Skin and soft tissues 352 | 17,230
Urinary Tract 326 | 16,678
Liver and Pancreas 323 | 16,750
Respiratory system 309 | 16,393
Cardiovascular System 263 | 15,192

Target Family

oGPCR 421 | 421
GPCR 406 | 408
Non-IDG 6 | 12,091
Enzyme 4 | 4,145

DTO Protein Class (0)

GPCR 837 | 837
Kinase 604 | 604
Ion channel 346 | 346
Nuclear hormone receptor 52 | 52

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Urotensin-2 receptor UTS2R Tchem GPCR -1.95094 62.5 182
Olfactory receptor 5H15 OR5H15 Tdark oGPCR 0.00000 35
Olfactory receptor 4F4 OR4F4 Tdark oGPCR 0.00000 45
Adhesion G-protein coupled receptor G1 ADGRG1 Tbio GPCR -1.94601 100.6 182
Olfactory receptor 4C12 OR4C12 Tdark oGPCR 0.31 0.30 74
Olfactory receptor 4K3 OR4K3 Tdark oGPCR 0.00000 0
Adrenocorticotropic hormone receptor MC2R Tclin GPCR -2.22640 172.4 223
Olfactory receptor 6C68 OR6C68 Tdark oGPCR 0.00000 49
Olfactory receptor 2M4 OR2M4 Tdark oGPCR 0.95 0.18 19
Olfactory receptor 2M2 OR2M2 Tdark oGPCR 0.00000 61