Development Level

Tbio 35 | 11,445
Tclin 31 | 613
Tchem 12 | 1,598

Collection

Ion Channel: IDG Consortium (T... 16 | 99

IMPC Phenotype

abnormal behavior 6 | 298
hyperactivity 5 | 148
increased bone mineral content 3 | 108
abnormal behavioral response t... 2 | 66
decreased body weight 2 | 161
decreased total body fat amoun... 2 | 207
impaired glucose tolerance 2 | 75
increased mean corpuscular vol... 2 | 92
preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal locomotor behavior 1 | 24
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
decreased basophil cell number 1 | 16
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac stroke volum... 1 | 6
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased mean platelet volume 1 | 25
enlarged epididymis 1 | 31
increased body length 1 | 32
increased circulating fructosa... 1 | 13
increased circulating magnesiu... 1 | 10
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
increased vertical activity 1 | 24
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened QT interval 1 | 4
shortened ST segment 1 | 10
tremors 1 | 39

Disease

Carcinoma 63 | 11,493
medulloblastoma, large-cell 44 | 6,241
ependymoma 40 | 4,679
atypical teratoid / rhabdoid tumor 38 | 5,112
glioblastoma 38 | 5,792
adult high grade glioma 36 | 3,801
group 3 medulloblastoma 33 | 4,104
oligodendroglioma 31 | 2,850
astrocytic glioma 28 | 2,597
primitive neuroectodermal tumor 28 | 3,035
Astrocytoma, Pilocytic 27 | 3,081
psoriasis 27 | 6,694
Multiple Sclerosis 26 | 540
Kidney cancer 25 | 2,613
Epilepsy 24 | 792
lung cancer 24 | 4,740
Eaton-Lambert syndrome 23 | 40
osteosarcoma 23 | 7,950
ovarian cancer 23 | 8,520
subependymal giant cell astrocytoma 21 | 2,287
lung carcinoma 19 | 2,843
pituitary cancer 19 | 1,972
Atrial Fibrillation 17 | 124
Long QT syndrome 17 | 39
Breast cancer 16 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
malignant mesothelioma 16 | 3,232
Pick disease 15 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
Intellectual disability 13 | 1,016
Seizures 13 | 596
pancreatic cancer 12 | 2,398
Brugada syndrome 11 | 29
Heart disease 11 | 306
colon cancer 11 | 1,478
cystic fibrosis 11 | 1,696
interstitial cystitis 11 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Autosomal recessive predisposition 10 | 1,442
Bipolar Disorder 9 | 666
Muscle hypotonia 9 | 571
Prolonged QT interval 9 | 15
Schizophrenia 9 | 1,160
invasive ductal carcinoma 9 | 2,951
non-small cell lung cancer 9 | 2,890
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Paroxysmal atrial fibrillation 8 | 14
Poor school performance 8 | 645
Syncope 8 | 22
ductal carcinoma in situ 8 | 1,745
lung adenocarcinoma 8 | 2,716
Cardiac Arrhythmia 7 | 103
Cardiac arrest 7 | 36
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Hypokalemia 7 | 52
Liver cancer 7 | 604
Mental Depression 7 | 333
Mental and motor retardation 7 | 608
Romano-Ward Syndrome 7 | 12
Ventricular Fibrillation 7 | 17
gastric carcinoma 7 | 807
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 6 | 21
Amyotrophic lateral sclerosis 6 | 451
Atrioventricular block 6 | 35
Brugada Syndrome (disorder) 6 | 15
Cerebellar Ataxia 6 | 304
Depressive disorder 6 | 409
Episodic ataxia 6 | 22
Familial atrial fibrillation 6 | 23
Long QT syndrome 1 6 | 20
Myoclonus 6 | 74
Schnyder Corneal Dystrophy 6 | 23
Sudden Cardiac Death 6 | 29
Timothy syndrome 6 | 11
Type 2 diabetes mellitus 6 | 272
adrenocortical carcinoma 6 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Angina Pectoris 5 | 32
Cardiomyopathy 5 | 116
Encephalitis 5 | 64
Failure to gain weight 5 | 365
Heart conduction disease 5 | 83
Hypertension 5 | 396
Infantile onset 5 | 238
Melanoma 5 | 711
Pediatric failure to thrive 5 | 365
Short QT syndrome 5 | 12
Skin cancer 5 | 469
Small head 5 | 374
Torsades de Pointes 5 | 8
active Crohn's disease 5 | 922
active ulcerative colitis 5 | 764
aldosterone-producing adenoma 5 | 665
breast carcinoma 5 | 1,638
sonic hedgehog group medulloblastoma 5 | 467
tuberculosis 5 | 2,010

Tissue

Endocrine System 76 | 18,159
Nervous System 75 | 16,725
Digestive Tract 73 | 17,369
Female tissues 71 | 17,400
Male tissues 70 | 17,142
Skin and soft tissues 70 | 17,230
Liver and Pancreas 67 | 16,750
Urinary Tract 64 | 16,678
Blood and immune system 63 | 16,909
Respiratory system 61 | 16,393
Cardiovascular System 59 | 15,192

Target Family

Ion Channel 68 | 344
Non-IDG 6 | 12,091
Enzyme 4 | 4,145

Compartment GO Term

voltage-gated potassium channe... 78 | 78
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paraneoplastic antigen Ma2 PNMA2 Tbio Non-IDG -2.92781 822.4 113
Calcium-activated potassium channel subunit beta-2 KCNMB2 Tbio Ion Channel 1.28 0.09 191
Leucine-rich repeat-containing protein 26 LRRC26 Tbio Ion Channel -1.02699 11.3 81
Leucine-rich glioma-inactivated protein 1 LGI1 Tbio Non-IDG -2.52790 342.7 207
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 HCN2 Tclin Ion Channel -1.16715 13.3 162
Potassium voltage-gated channel subfamily E member 3 KCNE3 Tbio Ion Channel -1.63683 41.4 75
Potassium voltage-gated channel subfamily D member 3 KCND3 Tclin Ion Channel -2.34610 217.9 162
Calcium-activated potassium channel subunit beta-4 KCNMB4 Tbio Ion Channel -0.98233 8.05 132
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 Tclin Ion Channel -2.48671 270.6 121