Development Level

Tclin 32 | 602
Tbio 30 | 10,625
Tchem 11 | 1,890
Tdark 1 | 7,003

Collection

Ion Channel: IDG Consortium (Targets) 14 | 102

IMPC Phenotype

abnormal behavior 3 | 226
decreased body weight 3 | 174
abnormal epididymis morphology 2 | 31
decreased circulating choleste... 2 | 85
decreased circulating serum al... 2 | 79
enlarged epididymis 2 | 27
hyperactivity 2 | 108
increased mean corpuscular vol... 2 | 91
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal response to tactile s... 1 | 16
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
decreased B cell number 1 | 30
decreased NK T cell number 1 | 28
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating calcium ... 1 | 33
decreased circulating fructosa... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating total pr... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased gamma-delta T cell n... 1 | 18
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased total body fat amoun... 1 | 186
impaired glucose tolerance 1 | 52
increased bone mineral content 1 | 92
increased caudal vertebrae num... 1 | 8
increased circulating fructosa... 1 | 11
increased circulating magnesiu... 1 | 10
increased exploration in new e... 1 | 56
increased vertical activity 1 | 18
limb grasping 1 | 35
preweaning lethality, complete... 1 | 633
tremors 1 | 34

Disease

medulloblastoma, large-cell 40 | 6,234
glioblastoma 35 | 5,572
atypical teratoid / rhabdoid tumor 30 | 4,369
oligodendroglioma 29 | 2,849
primitive neuroectodermal tumor 27 | 3,031
psoriasis 26 | 6,685
Multiple Sclerosis 25 | 498
pilocytic astrocytoma 25 | 3,086
ovarian cancer 24 | 8,491
Eaton-Lambert syndrome 23 | 40
Long QT syndrome 23 | 53
Carcinoma 22 | 2,147
Epilepsy 22 | 346
astrocytic glioma 22 | 2,241
ependymoma 22 | 2,514
osteosarcoma 22 | 7,933
subependymal giant cell astrocytoma 21 | 2,287
lung cancer 20 | 4,473
pediatric high grade glioma 20 | 2,712
pituitary cancer 20 | 1,972
lung carcinoma 19 | 2,844
Atrial Fibrillation 16 | 110
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
malignant mesothelioma 16 | 3,163
adult high grade glioma 15 | 2,148
Pick disease 14 | 1,893
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,988
medulloblastoma 14 | 1,524
sonic hedgehog group medulloblastoma 14 | 1,482
colon cancer 11 | 1,475
cystic fibrosis 11 | 1,670
interstitial cystitis 11 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
pancreatic cancer 11 | 2,300
posterior fossa group A ependymoma 11 | 1,511
Heart disease 10 | 279
group 3 medulloblastoma 10 | 2,254
invasive ductal carcinoma 10 | 2,950
Brugada syndrome 9 | 26
Intellectual disability 9 | 573
ductal carcinoma in situ 9 | 1,745
lung adenocarcinoma 9 | 2,714
Breast cancer 8 | 3,098
atypical teratoid/rhabdoid tumor 8 | 1,095
gastric carcinoma 8 | 832
non-small cell lung cancer 8 | 2,798
posterior fossa group B ependymoma 8 | 1,530
Amyotrophic Lateral Sclerosis 7 | 432
Congenital long QT syndrome 7 | 8
Hypokalemia 7 | 40
Romano-Ward Syndrome 7 | 12
Short QT syndrome 7 | 12
Brugada Syndrome (disorder) 6 | 15
Cardiac arrhythmia 6 | 26
Episodic ataxia 6 | 17
Familial atrial fibrillation 6 | 16
Long QT syndrome 1 6 | 12
Schnyder Corneal Dystrophy 6 | 24
Timothy syndrome 6 | 12
adrenocortical carcinoma 6 | 1,427
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
primary pancreatic ductal adenocarcinoma 6 | 1,271
ulcerative colitis 6 | 2,087
Angina pectoris 5 | 21
Bipolar Disorder 5 | 266
Cerebellar Ataxia 5 | 72
Down syndrome 5 | 548
Endometriosis 5 | 535
Heart conduction disease 5 | 65
Hypertension 5 | 293
Hypokalemic periodic paralysis 5 | 13
Muscle Weakness 5 | 92
Neurodegenerative disease 5 | 383
Type 2 diabetes mellitus 5 | 192
breast carcinoma 5 | 1,614
diabetes mellitus 5 | 1,663
fibroadenoma 5 | 557
group 4 medulloblastoma 5 | 1,875
Atrial Fibrillation Adverse Event 4 | 4
Encephalitis 4 | 54
Hypertensive disorder 4 | 58
Hypoglycemia 4 | 81
Paroxysmal atrial fibrillation 4 | 6
Sinoatrial node disease 4 | 7
Sudden infant death syndrome 4 | 34
Ventricular Fibrillation 4 | 10
active Crohn's disease 4 | 918
aldosterone-producing adenoma 4 | 664
astrocytoma 4 | 1,493
chronic rhinosinusitis 4 | 512
cutaneous lupus erythematosus 4 | 1,056
non primary Sjogren syndrome sicca 4 | 840
non-inflammatory breast cancer 4 | 208
pancreatic carcinoma 4 | 567
Cancer 3 | 2,346
Vascular disease 3 | 281
acute myeloid leukemia 3 | 785
nasopharyngeal carcinoma 3 | 1,056
nephrosclerosis 3 | 329
progressive supranuclear palsy 3 | 674

Tissue

Nervous System 73 | 18,560
Endocrine System 72 | 18,511
Liver and Pancreas 72 | 18,135
Blood and immune system 71 | 17,994
Cardiovascular System 71 | 17,957
Digestive Tract 71 | 18,472
Skin and soft tissues 71 | 18,114
Urinary Tract 71 | 18,443
Female tissues 70 | 18,646
Male tissues 70 | 17,968
Respiratory system 69 | 17,483

Target Family

Ion Channel 62 | 341
Non-IDG 6 | 11,969
Enzyme 4 | 4,146
Transporter 2 | 473

Compartment GO Term

voltage-gated potassium channe... 74 | 74
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.53667 324.2 196
Potassium voltage-gated channel subfamily H member 2 KCNH2 Tclin Ion Channel -3.19173 1625.2 221
Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C Tclin Ion Channel -2.72211 489.2 316
Kv channel-interacting protein 1 KCNIP1 Tbio Ion Channel -1.48426 31.4 205
Calcium-activated potassium channel subunit alpha-1 KCNMA1 Tclin Ion Channel -3.08349 1170.6 213
Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 Tclin Ion Channel -2.87621 876.7 339
Potassium voltage-gated channel subfamily D member 2 KCND2 Tclin Ion Channel -2.37752 236.9 255
Potassium voltage-gated channel subfamily KQT member 5 KCNQ5 Tclin Ion Channel -1.64476 42.0 170
Potassium voltage-gated channel subfamily C member 4 KCNC4 Tclin Ion Channel -1.73220 51.9 187
ATP-binding cassette sub-family C member 9 ABCC9 Tclin Transporter -1.57000 37.9 132