Development Level

Tbio 21 | 11,445
Tclin 15 | 613
Tchem 11 | 1,598
Tdark 9 | 6,588

Collection

Ion Channel: IDG Consortium (T... 12 | 99

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal embryo size 3 | 220
embryonic lethality prior to t... 3 | 278
abnormal behavior 2 | 298
edema 2 | 59
impaired glucose tolerance 2 | 75
increased startle reflex 2 | 112
preweaning lethality, incomple... 2 | 499
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal placenta vasculature 1 | 2
abnormal sensory capabilities-... 1 | 8
cardiovascular system phenotyp... 1 | 36
cyanosis 1 | 7
decreased circulating alkaline... 1 | 46
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
embryonic growth retardation 1 | 106
hemorrhage 1 | 23
hyperactivity 1 | 148
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
male infertility 1 | 123
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
respiratory system phenotype 1 | 2
small epididymis 1 | 3

Disease

Carcinoma 42 | 11,493
medulloblastoma, large-cell 29 | 6,241
psoriasis 28 | 6,694
atypical teratoid / rhabdoid tumor 26 | 5,112
glioblastoma 26 | 5,792
adult high grade glioma 24 | 3,801
osteosarcoma 24 | 7,950
ovarian cancer 24 | 8,520
Kidney cancer 22 | 2,613
ependymoma 22 | 4,679
group 3 medulloblastoma 22 | 4,104
primitive neuroectodermal tumor 20 | 3,035
oligodendroglioma 19 | 2,850
Astrocytoma, Pilocytic 18 | 3,081
Breast cancer 17 | 3,578
lung cancer 16 | 4,740
Epilepsy 15 | 792
astrocytic glioma 15 | 2,597
lung carcinoma 15 | 2,843
Malignant hyperthermia 14 | 26
Pick disease 14 | 1,894
subependymal giant cell astrocytoma 14 | 2,287
malignant mesothelioma 12 | 3,232
Bipolar Disorder 11 | 666
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
lung adenocarcinoma 11 | 2,716
pituitary cancer 11 | 1,972
Schizophrenia 10 | 1,160
Autosomal recessive predisposition 9 | 1,442
Heart disease 9 | 306
Liver cancer 9 | 604
colon cancer 9 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
Endometrial cancer 8 | 311
invasive ductal carcinoma 8 | 2,951
Intellectual disability 7 | 1,016
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
pancreatic cancer 7 | 2,398
Cancer 6 | 2,499
Hypertension 6 | 396
Hypertensive disorder 6 | 56
Seizures 6 | 596
Skin cancer 6 | 469
cystic fibrosis 6 | 1,696
tuberculosis 6 | 2,010
Angina Pectoris 5 | 32
Catecholaminergic polymorphic ventricular tachycardia 5 | 12
Dizziness 5 | 26
Liver Cirrhosis, Experimental 5 | 769
Melanoma 5 | 711
Myopathy 5 | 185
Syncope 5 | 22
Type 2 diabetes mellitus 5 | 272
Ventricular arrhythmia 5 | 27
Vertigo 5 | 29
acute quadriplegic myopathy 5 | 1,158
astrocytoma 5 | 1,146
non-small cell lung cancer 5 | 2,890
pediatric high grade glioma 5 | 1,064
ulcerative colitis 5 | 1,819
Amenorrhea Secondary to Ovarian Dysfunction 4 | 8
Atopic dermatitis 4 | 952
Atrophic vaginitis 4 | 14
Cerebellar Ataxia 4 | 304
Cognitive delay 4 | 608
Contraception 4 | 15
Corpus Luteum Insufficiency Syndrome 4 | 8
Dysfunctional uterine bleeding 4 | 9
Endometrial Hyperplasia Prevention 4 | 9
Endometrial carcinoma 4 | 15
Endometriosis 4 | 540
Global developmental delay 4 | 608
Infertility Secondary to Progesterone Deficiency 4 | 8
Male infertility 4 | 206
Menopausal flushing 4 | 17
Mental and motor retardation 4 | 608
Postmenopausal osteoporosis 4 | 19
Prevention of Premature Labor 4 | 9
Prinzmetal angina 4 | 6
Rheumatoid arthritis 4 | 1,191
Secondary malignant neoplasm of kidney 4 | 9
Secondary physiologic amenorrhea 4 | 32
Sudden death 4 | 16
Tachycardia, Ventricular 4 | 22
VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder) 4 | 5
active ulcerative colitis 4 | 764
chronic rhinosinusitis 4 | 512
cutaneous lupus erythematosus 4 | 1,057
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
nasopharyngeal carcinoma 4 | 1,058
Alzheimer's disease 3 | 658
Atrial Fibrillation 3 | 124
Cerebrovascular disease 3 | 238
Myocardial Ischemia 3 | 169
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
esophageal adenocarcinoma 3 | 737
head and neck cancer 3 | 271

Tissue

Endocrine System 56 | 18,159
Nervous System 53 | 16,725
Digestive Tract 52 | 17,369
Blood and immune system 51 | 16,909
Male tissues 51 | 17,142
Skin and soft tissues 51 | 17,230
Female tissues 50 | 17,400
Respiratory system 47 | 16,393
Liver and Pancreas 46 | 16,750
Urinary Tract 46 | 16,678
Cardiovascular System 40 | 15,192

Target Family

Ion Channel 33 | 344
Non-IDG 17 | 12,091
Enzyme 5 | 4,145
Transporter 1 | 473

Compartment GO Term

voltage-gated calcium channel ... 56 | 56
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Heat shock-related 70 kDa protein 2 HSPA2 Tbio Non-IDG -1.98655 104.3 162
Junctophilin-2 JPH2 Tbio Non-IDG -2.21890 163.0 229
Cation channel sperm-associated protein subunit zeta CATSPERZ Tdark Non-IDG 0.15 0.79 0
Potassium channel subfamily U member 1 KCNU1 Tbio Ion Channel -1.65772 43.3 45
Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G Tclin Ion Channel -2.16668 140.8 217
Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 Tbio Ion Channel -1.46356 25.4 471
Nucleoporin GLE1 GLE1 Tbio Non-IDG -2.24700 173.6 150
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 CD38 Tclin Enzyme -3.44680 2663.1 1493
Sorcin SRI Tbio Non-IDG -2.69915 481.5 119