Development Level

Tbio 181 | 10,625
Tchem 23 | 1,890
Tdark 20 | 7,003
Tclin 1 | 602

Collection

GPCR: IDG Consortium (Targets) 1 | 127
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 13 | 633
abnormal bone structure 9 | 131
abnormal bone mineralization 6 | 55
abnormal sleep behavior 6 | 63
decreased grip strength 6 | 123
embryonic lethality prior to t... 6 | 187
increased heart weight 6 | 37
decreased lean body mass 5 | 195
decreased total body fat amoun... 5 | 186
increased mean corpuscular vol... 5 | 91
increased or absent threshold ... 5 | 128
preweaning lethality, incomple... 5 | 260
abnormal behavior 4 | 226
abnormal lens morphology 4 | 73
decreased body weight 4 | 174
decreased bone mineral content 4 | 157
decreased circulating HDL chol... 4 | 77
increased bone mineral content 4 | 92
increased grip strength 4 | 83
abnormal QRS complex 3 | 25
abnormal behavioral response t... 3 | 52
abnormal embryo size 3 | 112
abnormal retinal pigmentation 3 | 61
decreased body length 3 | 108
decreased circulating insulin ... 3 | 75
decreased circulating triglyce... 3 | 83
decreased fasted circulating g... 3 | 49
decreased prepulse inhibition 3 | 52
increased bone mineral density 3 | 52
increased circulating alkaline... 3 | 119
increased lean body mass 3 | 107
increased sacral vertebrae num... 3 | 62
male infertility 3 | 62
abnormal epididymis morphology 2 | 31
abnormal limb bud morphology 2 | 15
abnormal neural tube closure 2 | 37
cataract 2 | 26
decreased B cell number 2 | 30
decreased CD8-positive, alpha-... 2 | 26
decreased NK T cell number 2 | 28
decreased T cell number 2 | 31
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 49
decreased circulating alanine ... 2 | 53
decreased erythrocyte cell num... 2 | 43
decreased gamma-delta T cell n... 2 | 18
decreased heart weight 2 | 44
decreased hemoglobin content 2 | 53
decreased lumbar vertebrae num... 2 | 62
decreased monocyte cell number 2 | 28
decreased respiratory quotient 2 | 12
decreased rib number 2 | 59
decreased startle reflex 2 | 48
decreased vertical activity 2 | 22
embryonic lethality prior to o... 2 | 148
enlarged epididymis 2 | 27
enlarged heart 2 | 111
hyperactivity 2 | 108
hypoactivity 2 | 89
impaired glucose tolerance 2 | 52
increased blood urea nitrogen ... 2 | 44
increased circulating potassiu... 2 | 31
increased circulating sodium l... 2 | 71
increased erythrocyte cell num... 2 | 26
increased hematocrit 2 | 36
increased mean corpuscular hem... 2 | 25
increased startle reflex 2 | 38
limb grasping 2 | 35
premature death 2 | 5
straub tail 2 | 26
abnormal coping response 1 | 12
abnormal cranium morphology 1 | 32
abnormal facial morphology 1 | 9
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal respiratory quotient 1 | 9
abnormal sensory capabilities-... 1 | 3
abnormal snout morphology 1 | 18
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 30
abnormal tooth morphology 1 | 24
decreased CD11b-low dendritic ... 1 | 3
decreased KLRG1-positive NK ce... 1 | 9
decreased NK cell number 1 | 16
decreased alpha-beta T cell nu... 1 | 12
decreased circulating creatini... 1 | 31
decreased effector memory CD8-... 1 | 24
decreased heart rate 1 | 10
decreased hematocrit 1 | 25
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased total retina thickne... 1 | 20
embryonic growth retardation 1 | 28
enlarged lymph nodes 1 | 27
female infertility 1 | 34
hemorrhage 1 | 12
hydrometra 1 | 13
impaired righting response 1 | 19
increased CD5-positive Ly6C-po... 1 | 4
increased circulating triglyce... 1 | 24

Disease

ovarian cancer 137 | 8,491
osteosarcoma 120 | 7,933
psoriasis 100 | 6,685
medulloblastoma, large-cell 95 | 6,234
glioblastoma 83 | 5,572
lung cancer 65 | 4,473
atypical teratoid / rhabdoid tumor 64 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 52 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 51 | 2,956
lung carcinoma 49 | 2,844
pilocytic astrocytoma 49 | 3,086
malignant mesothelioma 48 | 3,163
intraductal papillary-mucinous carcinoma (IPMC) 47 | 2,988
Breast cancer 44 | 3,098
invasive ductal carcinoma 41 | 2,950
pediatric high grade glioma 40 | 2,712
subependymal giant cell astrocytoma 40 | 2,287
Carcinoma 39 | 2,147
pancreatic cancer 39 | 2,300
Pick disease 37 | 1,893
ependymoma 37 | 2,514
astrocytic glioma 35 | 2,241
oligodendroglioma 34 | 2,849
adult high grade glioma 33 | 2,148
primitive neuroectodermal tumor 32 | 3,031
astrocytoma 31 | 1,493
diabetes mellitus 31 | 1,663
group 4 medulloblastoma 31 | 1,875
interstitial cystitis 31 | 2,299
non-small cell lung cancer 31 | 2,798
ductal carcinoma in situ 30 | 1,745
Cancer 29 | 2,346
lung adenocarcinoma 29 | 2,714
breast carcinoma 28 | 1,614
Alzheimer's disease 27 | 644
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,795
cystic fibrosis 24 | 1,670
pituitary cancer 24 | 1,972
Multiple myeloma 23 | 1,327
colon cancer 23 | 1,475
tuberculosis 23 | 1,563
ulcerative colitis 23 | 2,087
group 3 medulloblastoma 22 | 2,254
juvenile dermatomyositis 22 | 1,189
Waldenstrons macroglobulinemia 21 | 764
dermatomyositis 21 | 966
medulloblastoma 21 | 1,524
tuberculosis and treatment for 6 months 21 | 686
acute quadriplegic myopathy 20 | 1,157
posterior fossa group B ependymoma 20 | 1,530
Rheumatoid Arthritis 19 | 1,170
adrenocortical carcinoma 19 | 1,427
posterior fossa group A ependymoma 19 | 1,511
primary pancreatic ductal adenocarcinoma 19 | 1,271
Down syndrome 17 | 548
Neurodegenerative disease 17 | 383
Duchenne muscular dystrophy 15 | 602
Intellectual disability 15 | 573
primary Sjogren syndrome 15 | 788
spina bifida 15 | 1,064
aldosterone-producing adenoma 14 | 664
atypical teratoid/rhabdoid tumor 14 | 1,095
progressive supranuclear palsy 14 | 674
active Crohn's disease 13 | 918
acute myeloid leukemia 13 | 785
gastric carcinoma 13 | 832
esophageal adenocarcinoma 12 | 737
nasopharyngeal carcinoma 12 | 1,056
Kidney disease 11 | 397
Multiple Sclerosis 11 | 498
hereditary spastic paraplegia 11 | 313
mucosa-associated lymphoid tissue lymphoma 11 | 480
pancreatic carcinoma 11 | 567
Atopic dermatitis 10 | 944
active ulcerative colitis 10 | 477
cutaneous lupus erythematosus 10 | 1,056
sarcoidosis 10 | 368
Adenoma 9 | 165
IGA Glomerulonephritis 9 | 454
Obesity 9 | 616
non primary Sjogren syndrome sicca 9 | 840
Becker muscular dystrophy 8 | 187
Congenital disorder of glycosylation 8 | 53
Gaucher disease type 1 8 | 171
Mammary Neoplasms 8 | 410
Polycystic Ovary Syndrome 8 | 334
Prostatic Neoplasms 8 | 471
Schizophrenia 8 | 503
head and neck cancer and chronic obstructive pulmonary disease 8 | 237
sonic hedgehog group medulloblastoma 8 | 1,482
Colorectal Neoplasms 7 | 217
Hermansky-Pudlak syndrome 7 | 43
Liver disease 7 | 219
Microcephaly 7 | 149
Parkinson's disease 7 | 364
chronic lymphocytic leukemia 7 | 244
limb girdle muscular dystrophy 2A 7 | 156
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
gastric cancer 6 | 436
hepatocellular carcinoma 6 | 550

Tissue

Endocrine System 221 | 18,511
Cardiovascular System 220 | 17,957
Female tissues 220 | 18,646
Nervous System 220 | 18,560
Urinary Tract 220 | 18,443
Blood and immune system 219 | 17,994
Digestive Tract 219 | 18,472
Liver and Pancreas 219 | 18,135
Male tissues 219 | 17,968
Respiratory system 218 | 17,483
Skin and soft tissues 216 | 18,114

Target Family

Non-IDG 158 | 11,969
Enzyme 50 | 4,146
Transporter 9 | 473
GPCR 4 | 408
Kinase 4 | 634

Compartment GO Term

trans-Golgi network 225 | 225
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Trafficking protein particle complex subunit 9 TRAPPC9 Tbio Non-IDG -2.14008 133.3 71
Inositol polyphosphate 5-phosphatase K INPP5K Tbio Enzyme -0.84616 8.89 74
Cyclin-dependent kinase inhibitor 2A CDKN2A Tbio Enzyme -3.70375 8561.3 896
Vacuolar protein sorting-associated protein 53 homolog VPS53 Tbio Non-IDG -0.76155 5.77 94
Conserved oligomeric Golgi complex subunit 5 COG5 Tbio Non-IDG -0.92957 8.17 15
ADP-ribosylation factor-like protein 1 ARL1 Tbio Enzyme -0.40932 3.58 187
Carboxypeptidase E CPE Tbio Enzyme -2.99888 983.1 216
WD repeat domain phosphoinositide-interacting protein 1 WIPI1 Tbio Non-IDG -1.58031 37.0 174
Calcium-binding protein 8 CALN1 Tbio Non-IDG -0.86575 6.50 101
Sodium/potassium/calcium exchanger 5 SLC24A5 Tbio Transporter -1.59093 38.9 49