Development Level

Tbio 8 | 11,445

IMPC Phenotype

decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
increased circulating alkaline... 1 | 122
increased mean corpuscular hem... 1 | 36
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 8 | 11,493
osteosarcoma 7 | 7,950
Astrocytoma, Pilocytic 5 | 3,081
Kidney cancer 5 | 2,613
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
medulloblastoma, large-cell 5 | 6,241
Anemia 4 | 365
Anemia, Hemolytic 4 | 55
Breast cancer 4 | 3,578
Congenital hemolytic anemia 4 | 32
Hereditary elliptocytosis 4 | 22
primitive neuroectodermal tumor 4 | 3,035
Anemia, hereditary spherocytic hemolytic 3 | 5
Elliptocytosis, Hereditary 3 | 9
Hereditary spherocytosis 3 | 16
Liver cancer 3 | 604
Melanoma 3 | 711
Spherocytosis 3 | 5
lung adenocarcinoma 3 | 2,716
oligodendroglioma 3 | 2,850
psoriasis 3 | 6,694
Autosomal recessive predisposition 2 | 1,442
Dull intelligence 2 | 645
Elliptocytosis found 2 | 7
Endometrial cancer 2 | 311
Icterus 2 | 82
Increased bilirubin level (finding) 2 | 18
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Poor school performance 2 | 645
Reticulocytosis 2 | 20
Skin cancer 2 | 469
Splenomegaly 2 | 190
Type 2 diabetes mellitus 2 | 272
acute quadriplegic myopathy 2 | 1,158
astrocytic glioma 2 | 2,597
ductal carcinoma in situ 2 | 1,745
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
mucosa-associated lymphoid tissue lymphoma 2 | 484
ovarian cancer 2 | 8,520
pancreatic cancer 2 | 2,398
subependymal giant cell astrocytoma 2 | 2,287
Acquired metabolic disease 1 | 336
Aggressive behavior 1 | 75
Aggressive reaction 1 | 75
Autistic Disorder 1 | 364
Azoospermia 1 | 110
Brugada syndrome 1 | 29
Byzanthine arch palate 1 | 194
Craniosynostosis 1 | 74
DOID:2627 1 | 94
DOID:9917 1 | 31
Down syndrome 1 | 499
Doyne honeycomb retinal dystrophy 1 | 9
Gestational diabetes 1 | 26
Globe disease 1 | 67
Hyperactive behavior 1 | 91
Hypercalcemia 1 | 59
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Large intestine cancer 1 | 126
Lung Neoplasms 1 | 232
Lymphoid leukemia 1 | 160
Major Depressive Disorder 1 | 301
Malaria 1 | 160
Malformed pinnae 1 | 37
Metabolic acidosis 1 | 90
Moderate mental retardation (I.Q. 35-49) 1 | 28
Mood Disorders 1 | 184
Muscle Spasticity 1 | 195
Neuropathy 1 | 261
Nonorganic psychosis 1 | 84
Osteomalacia 1 | 35
Osteoporosis 1 | 363
Physical aggression 1 | 76
Polycystic ovary syndrome 1 | 360
Postpartum depression 1 | 8
Pre-Eclampsia 1 | 68
Preauricular Fistulae, Congenital 1 | 27
Preauricular dimple 1 | 27
Preauricular sinus 1 | 27
Psychotic Disorders 1 | 151
Rickets 1 | 49
Sickle Cell Anemia 1 | 53
Sleep disturbances 1 | 37
Status Epilepticus 1 | 98
Waldenstrons macroglobulinemia 1 | 765
Weight Gain 1 | 100
breast carcinoma 1 | 1,638
cystic fibrosis 1 | 1,696
hepatocellular carcinoma 1 | 547
sarcoidosis 1 | 370
tuberculosis and treatment for 6 months 1 | 409

Tissue

Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Skin and soft tissues 8 | 17,230
Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Male tissues 7 | 17,142
Urinary Tract 7 | 16,678
Nervous System 6 | 16,725
Respiratory system 6 | 16,393

Target Family

Non-IDG 8 | 12,091

Compartment GO Term

spectrin-associated cytoskelet... 8 | 8
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Spectrin beta chain, non-erythrocytic 1 SPTBN1 Tbio Non-IDG -1.69564 46.5 98
Ankyrin-1 ANK1 Tbio Non-IDG -2.56553 282.2 214
Ankyrin-3 ANK3 Tbio Non-IDG -2.25280 172.9 170
Protein 4.1 EPB41 Tbio Non-IDG -2.85166 692.3 245
Spectrin beta chain, erythrocytic SPTB Tbio Non-IDG -2.45982 275.1 59
Spectrin alpha chain, erythrocytic 1 SPTA1 Tbio Non-IDG -2.93650 850.7 86
Dematin DMTN Tbio Non-IDG -1.73686 56.6 158
Ammonium transporter Rh type B RHBG Tbio Non-IDG -1.63669 46.4 105