Development Level

Tbio 149 | 11,651
Tchem 27 | 1,388
Tdark 18 | 6,593
Tclin 7 | 612

IMPC Phenotype

preweaning lethality, complete... 18 | 979
embryonic lethality prior to o... 12 | 239
embryonic lethality prior to t... 9 | 278
abnormal embryo size 5 | 220
preweaning lethality, incomple... 4 | 499
abnormal head morphology 2 | 10
abnormal startle reflex 2 | 15
decreased body weight 2 | 161
decreased caudal vertebrae num... 2 | 53
decreased circulating alanine ... 2 | 47
decreased circulating glucose ... 2 | 126
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased prepulse inhibition 2 | 82
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
hypoactivity 2 | 132
increased bone mineral density 2 | 72
increased circulating sodium l... 2 | 71
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
mammalian phenotype 2 | 17
abnormal blood vessel morpholo... 1 | 5
abnormal bone mineralization 1 | 38
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal skin morphology 1 | 50
abnormal spinal cord morpholog... 1 | 9
abnormal stomach morphology 1 | 10
abnormal tooth morphology 1 | 24
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body length 1 | 101
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased coping response 1 | 8
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased total retina thickne... 1 | 17
enlarged heart 1 | 210
increased bone mineral content 1 | 108
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased grip strength 1 | 41
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
male infertility 1 | 123
polycystic kidney 1 | 15
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97

Disease

Carcinoma 108 | 11,493
ovarian cancer 106 | 8,520
psoriasis 99 | 6,694
osteosarcoma 92 | 7,950
lung cancer 91 | 4,740
Cancer 76 | 2,499
medulloblastoma, large-cell 76 | 6,241
malignant mesothelioma 75 | 3,232
Breast cancer 74 | 3,578
group 3 medulloblastoma 71 | 4,104
glioblastoma 68 | 5,792
non-small cell lung cancer 64 | 2,890
atypical teratoid / rhabdoid tumor 62 | 5,112
lung adenocarcinoma 58 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 53 | 3,291
primitive neuroectodermal tumor 52 | 3,035
invasive ductal carcinoma 47 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 46 | 2,989
colon cancer 40 | 1,478
adrenocortical carcinoma 38 | 1,428
ductal carcinoma in situ 38 | 1,745
ependymoma 38 | 4,679
breast carcinoma 36 | 1,638
adult high grade glioma 31 | 3,801
Kidney cancer 30 | 2,613
diabetes mellitus 29 | 1,728
pancreatic cancer 29 | 2,398
oligodendroglioma 26 | 2,850
Waldenstrons macroglobulinemia 24 | 765
nasopharyngeal carcinoma 23 | 1,058
pediatric high grade glioma 23 | 1,064
Multiple myeloma 22 | 1,332
Endometriosis 21 | 540
Intellectual disability 21 | 1,016
Schizophrenia 21 | 1,160
acute quadriplegic myopathy 21 | 1,158
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
pituitary cancer 21 | 1,972
ulcerative colitis 21 | 1,819
Breast Neoplasms 20 | 445
Pick disease 20 | 1,894
astrocytoma 20 | 1,146
subependymal giant cell astrocytoma 20 | 2,287
Autosomal recessive predisposition 19 | 1,442
Mammary Neoplasms 19 | 425
lung carcinoma 19 | 2,843
Astrocytoma, Pilocytic 18 | 3,081
tuberculosis 18 | 2,010
Short stature 17 | 531
acute myeloid leukemia 17 | 783
Small head 16 | 374
group 4 medulloblastoma 16 | 1,855
hepatocellular carcinoma 16 | 547
Atopic dermatitis 15 | 952
Dull intelligence 15 | 645
Low intelligence 15 | 645
Mental Retardation 15 | 645
Mental deficiency 15 | 645
Poor school performance 15 | 645
Rheumatoid arthritis 15 | 1,191
astrocytic glioma 15 | 2,597
cystic fibrosis 15 | 1,696
dermatomyositis 15 | 966
non-small cell lung carcinoma 15 | 317
Cognitive delay 14 | 608
Cryptorchidism 14 | 296
Epilepsy 14 | 792
Global developmental delay 14 | 608
Mental and motor retardation 14 | 608
Seizures 14 | 596
Xeroderma pigmentosum 14 | 43
Cockayne syndrome 13 | 60
Prostatic Neoplasms 13 | 495
cutaneous lupus erythematosus 13 | 1,057
interstitial cystitis 13 | 2,312
juvenile dermatomyositis 13 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Colorectal Neoplasms 12 | 243
Fetal Growth Retardation 12 | 189
Infant, Small for Gestational Age 12 | 176
Intrauterine retardation 12 | 176
Lung Neoplasms 12 | 232
Melanoma 12 | 711
Nijmegen breakage syndrome 11 | 24
Werner syndrome 11 | 29
non primary Sjogren syndrome sicca 11 | 891
pancreatic carcinoma 11 | 562
Alzheimer's disease 10 | 658
Ataxia telangiectasia 10 | 34
Down syndrome 10 | 499
Seckel syndrome 10 | 34
Stomach Neoplasms 10 | 300
aldosterone-producing adenoma 10 | 665
primary Sjogren syndrome 10 | 735
Failure to gain weight 9 | 365
Male infertility 9 | 206
Obesity 9 | 678
Pediatric failure to thrive 9 | 365
Strabismus 9 | 270
esophageal adenocarcinoma 9 | 737

Tissue

Endocrine System 198 | 18,159
Blood and immune system 196 | 16,909
Female tissues 196 | 17,400
Digestive Tract 194 | 17,369
Male tissues 190 | 17,142
Skin and soft tissues 190 | 17,230
Urinary Tract 190 | 16,678
Nervous System 187 | 16,725
Respiratory system 187 | 16,393
Liver and Pancreas 186 | 16,750
Cardiovascular System 181 | 15,192

Target Family

Non-IDG 123 | 12,091
Transcription Factor 33 | 1,400
Enzyme 22 | 4,145
Epigenetic 13 | 242
Kinase 8 | 634
GPCR 1 | 408
Nuclear Receptor 1 | 48

Compartment GO Term

protein-DNA complex 201 | 201
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Eukaryotic translation initiation factor 1 EIF1 Tbio Non-IDG -2.06392 118.5 92
Zinc finger and BTB domain-containing protein 17 ZBTB17 Tbio Transcription Factor -1.57508 40.4 92
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610