Development Level

Tbio 123 | 10,625
Tchem 31 | 1,890
Tdark 22 | 7,003
Tclin 4 | 602

IMPC Term

preweaning lethality, complete... 14 | 633
embryonic lethality prior to o... 6 | 148
embryonic lethality prior to t... 4 | 187
increased circulating sodium l... 3 | 71
abnormal embryo size 2 | 112
abnormal head morphology 2 | 10
abnormal startle reflex 2 | 14
decreased body length 2 | 108
decreased caudal vertebrae num... 2 | 49
decreased fasted circulating g... 2 | 49
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
hypoactivity 2 | 89
increased grip strength 2 | 83
abnormal blood vessel morpholo... 1 | 2
abnormal bone mineralization 1 | 55
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal maxilla morphology 1 | 16
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal tooth morphology 1 | 24
anophthalmia 1 | 20
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
decreased Ly6C low monocyte nu... 1 | 23
decreased body weight 1 | 174
decreased circulating alanine ... 1 | 53
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating total pr... 1 | 41
decreased coping response 1 | 5
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased heart rate variabili... 1 | 11
edema 1 | 11
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating fructosa... 1 | 11
increased effector memory CD4-... 1 | 15
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased or absent threshold ... 1 | 128
increased plasma cell number 1 | 5
male infertility 1 | 62
microphthalmia 1 | 15
polydactyly 1 | 22
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
shortened head 1 | 2

Disease

ovarian cancer 96 | 8,492
psoriasis 90 | 6,685
osteosarcoma 81 | 7,933
lung cancer 77 | 4,473
medulloblastoma, large-cell 68 | 6,234
malignant mesothelioma 66 | 3,163
Cancer 64 | 2,346
Breast cancer 58 | 3,099
glioblastoma 58 | 5,572
non-small cell lung cancer 55 | 2,798
lung adenocarcinoma 51 | 2,714
atypical teratoid / rhabdoid tumor 49 | 4,369
primitive neuroectodermal tumor 49 | 3,031
intraductal papillary-mucinous neoplasm (IPMN) 48 | 3,289
group 3 medulloblastoma 45 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 44 | 2,988
invasive ductal carcinoma 44 | 2,950
pediatric high grade glioma 42 | 2,712
colon cancer 38 | 1,475
adrenocortical carcinoma 35 | 1,427
ductal carcinoma in situ 35 | 1,745
breast carcinoma 29 | 1,614
diabetes mellitus 24 | 1,663
pancreatic cancer 24 | 2,300
oligodendroglioma 23 | 2,849
Carcinoma 22 | 2,147
Waldenstrons macroglobulinemia 22 | 765
nasopharyngeal carcinoma 22 | 1,056
posterior fossa group A ependymoma 21 | 1,511
sonic hedgehog group medulloblastoma 21 | 1,482
ulcerative colitis 21 | 2,087
Endometriosis 20 | 535
astrocytoma 19 | 1,493
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,956
Multiple myeloma 18 | 1,328
Pick disease 18 | 1,893
pituitary cancer 18 | 1,972
Mammary Neoplasms 17 | 410
acute quadriplegic myopathy 17 | 1,157
pilocytic astrocytoma 17 | 3,086
group 4 medulloblastoma 16 | 1,875
lung carcinoma 16 | 2,844
acute myeloid leukemia 15 | 785
atypical teratoid/rhabdoid tumor 15 | 1,095
non-small cell lung carcinoma 15 | 413
subependymal giant cell astrocytoma 15 | 2,287
Atopic dermatitis 14 | 944
dermatomyositis 14 | 967
ependymoma 14 | 2,514
Rheumatoid Arthritis 13 | 1,171
cystic fibrosis 13 | 1,670
hepatocellular carcinoma 13 | 550
cutaneous lupus erythematosus 12 | 1,056
interstitial cystitis 12 | 2,299
Nijmegen breakage syndrome 11 | 23
Seckel syndrome 11 | 35
astrocytic glioma 11 | 2,241
pancreatic carcinoma 11 | 567
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,795
tuberculosis 11 | 1,563
Cockayne syndrome 10 | 54
Colorectal Neoplasms 10 | 217
Intellectual disability 10 | 573
Werner syndrome 10 | 29
aldosterone-producing adenoma 10 | 664
inflammatory breast cancer 10 | 404
juvenile dermatomyositis 10 | 1,189
Ataxia telangiectasia 9 | 32
IGA Glomerulonephritis 9 | 454
Lung Neoplasms 9 | 171
primary Sjogren syndrome 9 | 789
Colonic Neoplasms 8 | 126
Liver carcinoma 8 | 217
Meier-Gorlin syndrome 8 | 12
Melanoma 8 | 261
Obesity 8 | 616
Peripheral Neuropathy 8 | 303
Prostatic Neoplasms 8 | 471
esophageal adenocarcinoma 8 | 737
medulloblastoma 8 | 1,524
non primary Sjogren syndrome sicca 8 | 840
spina bifida 8 | 1,064
tuberculosis and treatment for 6 months 8 | 686
Fanconi's anemia 7 | 50
Male infertility 7 | 170
Multiple Sclerosis 7 | 498
Schizophrenia 7 | 503
Stomach Neoplasms 7 | 282
Toxic encephalopathy 7 | 131
adult high grade glioma 7 | 2,148
chronic lymphocytic leukemia 7 | 244
gastric cancer 7 | 436
glioblastoma multiforme 7 | 347
Alzheimer's disease 6 | 644
Cerebrovascular disease 6 | 231
Crohn's disease 6 | 304
Down syndrome 6 | 548
Kidney disease 6 | 397
gastric carcinoma 6 | 832
progressive supranuclear palsy 6 | 674

Tissue

Female tissues 178 | 18,647
Blood and immune system 177 | 17,995
Endocrine System 177 | 18,512
Nervous System 177 | 18,561
Urinary Tract 177 | 18,444
Male tissues 176 | 17,969
Cardiovascular System 175 | 17,958
Digestive Tract 175 | 18,473
Liver and Pancreas 173 | 18,136
Respiratory system 172 | 17,484
Skin and soft tissues 165 | 18,115

Target Family

Non-IDG 119 | 11,969
Transcription Factor 24 | 1,400
Enzyme 19 | 4,146
Epigenetic 12 | 242
Kinase 6 | 634

Compartment GO Term

protein-DNA complex 180 | 180
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA polymerase delta catalytic subunit POLD1 Tclin Enzyme -2.02098 96.6 198
DNA replication complex GINS protein SLD5 GINS4 Tdark Non-IDG -1.25647 17.0 45
Protection of telomeres protein 1 POT1 Tbio Non-IDG -1.79851 58.3 169
Cell division control protein 6 homolog CDC6 Tchem Non-IDG -2.49821 321.6 473
Probable global transcription activator SNF2L1 SMARCA1 Tbio Non-IDG -2.18842 137.5 94
TERF1-interacting nuclear factor 2 TINF2 Tbio Non-IDG -1.98986 89.8 128
Myogenin MYOG Tbio Transcription Factor -2.95734 772.0 578
Replication protein A 70 kDa DNA-binding subunit RPA1 Tchem Non-IDG -2.46324 281.9 299
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.12726 13094.7 961
Myc proto-oncogene protein MYC Tbio Transcription Factor -4.09050 11730.8 2241