Development Level

Tbio 23 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 3 | 278
abnormal embryo size 2 | 220
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
abnormal skin morphology 1 | 50
cataract 1 | 92
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
embryonic growth retardation 1 | 106
increased circulating creatini... 1 | 38
increased grip strength 1 | 41
prenatal lethality prior to he... 1 | 87

Disease

group 3 medulloblastoma 20 | 4,104
Carcinoma 19 | 11,493
adrenocortical carcinoma 18 | 1,428
non-small cell lung cancer 18 | 2,890
ovarian cancer 18 | 8,520
malignant mesothelioma 17 | 3,232
medulloblastoma, large-cell 17 | 6,241
psoriasis 17 | 6,694
lung cancer 16 | 4,740
primitive neuroectodermal tumor 15 | 3,035
Breast cancer 14 | 3,578
atypical teratoid / rhabdoid tumor 14 | 5,112
glioblastoma 14 | 5,792
osteosarcoma 13 | 7,950
Cancer 12 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
lung adenocarcinoma 11 | 2,716
nasopharyngeal carcinoma 11 | 1,058
invasive ductal carcinoma 10 | 2,951
adult high grade glioma 9 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
Meier-Gorlin syndrome 8 | 10
colon cancer 8 | 1,478
EAR, PATELLA, SHORT STATURE SYNDROME 7 | 7
Endometriosis 7 | 540
ductal carcinoma in situ 7 | 1,745
Atopic dermatitis 6 | 952
Autosomal recessive predisposition 6 | 1,442
ependymoma 6 | 4,679
oligodendroglioma 6 | 2,850
pediatric high grade glioma 6 | 1,064
Fetal Growth Retardation 5 | 189
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Isolated growth hormone deficiency 5 | 30
Multiple myeloma 5 | 1,332
Seckel syndrome 5 | 34
Small head 5 | 374
Birth length less than 3rd percentile 4 | 6
Congenital small ears 4 | 48
Delayed bone age 4 | 136
Failure to gain weight 4 | 365
Pediatric failure to thrive 4 | 365
Slender, gracile long tubular bones 4 | 21
astrocytoma 4 | 1,146
Astrocytoma, Pilocytic 3 | 3,081
Congenital hypoplasia of breast 3 | 25
Cryptorchidism 3 | 296
Decreased projection of maxilla 3 | 66
Deficiency of upper jaw bones 3 | 66
Feeding difficulties 3 | 127
Gastroesophageal reflux disease 3 | 110
Heartburn 3 | 78
Hypertrophy of clitoris 3 | 40
Hypoplasia of the maxilla 3 | 66
Hypoplastic mandible condyle 3 | 275
Hypotrophic maxilla 3 | 66
Mandibular hypoplasia 3 | 275
Maxillary retrognathia 3 | 66
Microcephaly 3 | 166
Micrognathism 3 | 275
Microstomia 3 | 78
Retrusion of upper jaw bones 3 | 66
Waldenstrons macroglobulinemia 3 | 765
breast carcinoma 3 | 1,638
primary Sjogren syndrome 3 | 735
Absent bone maturation in sternum 2 | 4
Absent sternal ossification 2 | 4
Acquired immunodeficiency syndrome 2 | 197
Cervix endometriosis 2 | 3
Cleft Palate 2 | 271
Colonic Neoplasms 2 | 142
Congenital hypoplasia of penis 2 | 176
Full lower lip 2 | 64
Genu varum 2 | 29
Kidney cancer 2 | 2,613
Low set ears 2 | 181
Melanoacanthoma 2 | 2
Patella aplasia-hypoplasia 2 | 12
Polycystic ovary syndrome 2 | 360
Premature ovarian failure 2 | 65
Prominent lower lip 2 | 64
Pulmonary emphysema 2 | 48
Rothmund-Thomson syndrome 2 | 19
Short ribs 2 | 30
Small labia majora 2 | 16
Triangular face 2 | 58
acute myeloid leukemia 2 | 783
esophageal adenocarcinoma 2 | 737
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
non diabetic and post-ischemic heart failure 2 | 200
pancreatic cancer 2 | 2,398
ulcerative colitis 2 | 1,819
Autosomal recessive polycystic kidney disease 1 | 41
Burkitt Lymphoma 1 | 20
Lactose intolerance 1 | 7
MASA syndrome 1 | 8
OVARIAN DYSGENESIS 4 1 | 1
Short thorax 1 | 21

Tissue

Blood and immune system 25 | 16,909
Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Respiratory system 25 | 16,393
Skin and soft tissues 25 | 17,230
Urinary Tract 25 | 16,678
Cardiovascular System 24 | 15,192

Target Family

Non-IDG 18 | 12,091
Enzyme 3 | 4,145
Kinase 2 | 634
TF/Epigenetic 1 | 38
Transcription Factor 1 | 1,400

Compartment GO Term

pre-replicative complex 25 | 25
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Origin recognition complex subunit 1 ORC1 Tbio Non-IDG -1.42573 28.0 148
Origin recognition complex subunit 5 ORC5 Tbio Non-IDG -1.50983 31.3 71
DNA replication factor Cdt1 CDT1 Tbio Non-IDG -2.19436 151.0 136
Cell division control protein 45 homolog CDC45 Tbio Non-IDG -2.10913 117.6 265
DNA replication licensing factor MCM2 MCM2 Tbio Non-IDG -2.41622 246.0 777
Cell division cycle 7-related protein kinase CDC7 Tchem Kinase -2.24065 184.7 222
DNA replication licensing factor MCM6 MCM6 Tbio Non-IDG -1.99059 90.3 260
Origin recognition complex subunit 3 ORC3 Tbio Non-IDG -1.25409 17.4 192
Lamin-B2 LMNB2 Tbio Non-IDG -2.00661 99.1 208
Myc proto-oncogene protein MYC Tbio Transcription Factor -4.11278 12358.0 2705