Development Level

Tbio 17 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
abnormal embryo size 2 | 220
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
abnormal skin morphology 1 | 50
cataract 1 | 92
decreased circulating alanine ... 1 | 47
embryonic growth retardation 1 | 106
increased grip strength 1 | 41

Disease

adrenocortical carcinoma 16 | 1,428
group 3 medulloblastoma 15 | 4,104
non-small cell lung cancer 15 | 2,890
lung cancer 14 | 4,740
malignant mesothelioma 14 | 3,232
ovarian cancer 14 | 8,520
Carcinoma 13 | 11,493
medulloblastoma, large-cell 13 | 6,241
psoriasis 13 | 6,694
glioblastoma 12 | 5,792
atypical teratoid / rhabdoid tumor 11 | 5,112
primitive neuroectodermal tumor 11 | 3,035
Breast cancer 10 | 3,578
Cancer 10 | 2,499
lung adenocarcinoma 10 | 2,716
adult high grade glioma 9 | 3,801
invasive ductal carcinoma 9 | 2,951
nasopharyngeal carcinoma 9 | 1,058
osteosarcoma 9 | 7,950
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
EAR, PATELLA, SHORT STATURE SYNDROME 6 | 7
Meier-Gorlin syndrome 6 | 10
colon cancer 6 | 1,478
Atopic dermatitis 5 | 952
Endometriosis 5 | 540
ependymoma 5 | 4,679
oligodendroglioma 5 | 2,850
Autosomal recessive predisposition 4 | 1,442
Fetal Growth Retardation 4 | 189
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Isolated growth hormone deficiency 4 | 30
Seckel syndrome 4 | 34
Small head 4 | 374
astrocytoma 4 | 1,146
Birth length less than 3rd percentile 3 | 6
Congenital small ears 3 | 48
Delayed bone age 3 | 136
Failure to gain weight 3 | 365
Feeding difficulties 3 | 127
Multiple myeloma 3 | 1,332
Pediatric failure to thrive 3 | 365
Slender, gracile long tubular bones 3 | 21
breast carcinoma 3 | 1,638
pediatric high grade glioma 3 | 1,064
Astrocytoma, Pilocytic 2 | 3,081
Cervix endometriosis 2 | 3
Congenital hypoplasia of breast 2 | 25
Cryptorchidism 2 | 296
Decreased projection of maxilla 2 | 66
Deficiency of upper jaw bones 2 | 66
Gastroesophageal reflux disease 2 | 110
Heartburn 2 | 78
Hypertrophy of clitoris 2 | 40
Hypoplasia of the maxilla 2 | 66
Hypoplastic mandible condyle 2 | 275
Hypotrophic maxilla 2 | 66
Kidney cancer 2 | 2,613
Mandibular hypoplasia 2 | 275
Maxillary retrognathia 2 | 66
Melanoacanthoma 2 | 2
Microcephaly 2 | 166
Micrognathism 2 | 275
Microstomia 2 | 78
Polycystic ovary syndrome 2 | 360
Pulmonary emphysema 2 | 48
Retrusion of upper jaw bones 2 | 66
Rothmund-Thomson syndrome 2 | 19
Triangular face 2 | 58
Waldenstrons macroglobulinemia 2 | 765
interstitial cystitis 2 | 2,312
pancreatic cancer 2 | 2,398
primary Sjogren syndrome 2 | 735
ulcerative colitis 2 | 1,819
Acquired immunodeficiency syndrome 1 | 197
Dyspnea 1 | 76
Genu varum 1 | 29
Gout 1 | 106
HIV Infections 1 | 102
Long narrow head 1 | 75
Lymphadenopathy 1 | 62
Melanoma 1 | 711
Microretrognathia 1 | 13
Motor delay 1 | 147
Narrow cranium shape 1 | 75
Narrow head shape 1 | 75
Narrow skull shape 1 | 75
Narrow thorax 1 | 53
Neuronal ceroid lipofuscinosis 1 | 28
No development of motor milestones 1 | 147
Nonsyndromic deafness 1 | 142
Range of joint movement increased 1 | 32
Recurrent respiratory infections 1 | 141
Seborrheic keratosis 1 | 8
Tracheomalacia 1 | 22
Turridolichocephaly 1 | 75
posterior fossa group A ependymoma 1 | 468
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 19 | 16,909
Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Respiratory system 19 | 16,393
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678
Cardiovascular System 18 | 15,192

Target Family

Non-IDG 15 | 12,091
Enzyme 2 | 4,145
Kinase 2 | 634

Compartment GO Term

pre-primosome complex 19 | 19
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cyclin-dependent kinase 2 CDK2 Tchem Kinase -3.44266 2522.8 1114
DNA replication licensing factor MCM2 MCM2 Tbio Non-IDG -2.41622 246.0 777
DNA replication licensing factor MCM7 MCM7 Tbio Non-IDG -2.60651 387.2 575
Cell division control protein 6 homolog CDC6 Tbio Non-IDG -2.51683 336.8 574
DNA replication licensing factor MCM5 MCM5 Tbio Non-IDG -1.91809 76.3 508
DNA replication licensing factor MCM3 MCM3 Tbio Non-IDG -2.04750 101.5 390
DNA replication licensing factor MCM4 MCM4 Tbio Non-IDG -1.94022 86.8 319
Cell division control protein 45 homolog CDC45 Tbio Non-IDG -2.10913 117.6 265
Geminin GMNN Tbio Non-IDG -2.21128 180.7 263
Cell division cycle 7-related protein kinase CDC7 Tchem Kinase -2.24065 184.7 222