Development Level

Tbio 5 | 11,445

IMPC Phenotype

abnormal bone structure 1 | 187
decreased bone mineral content 1 | 151
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
increased fasted circulating g... 1 | 76

Disease

Carcinoma 4 | 11,493
Kidney cancer 3 | 2,613
malignant mesothelioma 3 | 3,232
ovarian cancer 3 | 8,520
psoriasis 3 | 6,694
Astrocytoma, Pilocytic 2 | 3,081
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
osteosarcoma 2 | 7,950
subependymal giant cell astrocytoma 2 | 2,287
Absent reflex 1 | 92
Absent tendon reflex 1 | 92
Amyotrophic lateral sclerosis type 8 1 | 10
Anal fistula 1 | 6
Autosomal dominant Robinow syndrome 2 1 | 22
Autosomal recessive predisposition 1 | 1,442
Blind Vision 1 | 111
Blindness, Legal 1 | 110
Centronuclear myopathy 1 | 27
Chronic kidney disease stage 5 1 | 31
Constipation 1 | 181
Danon disease 1 | 8
Diffuse mesangial sclerosis (disorder) 1 | 7
Duchenne muscular dystrophy 1 | 601
Ecthyma 1 | 2
Edema 1 | 81
Endometrial cancer 1 | 311
Esophageal atresia 1 | 43
Familial isolated deficiency of vitamin E 1 | 6
Familial nephrotic syndrome 1 | 6
Gastric outlet obstruction 1 | 6
Hiatus hernia 1 | 7
Hirschsprung's disease 1 | 46
Hypoplasia of iris 1 | 10
Hypoplasia of the ciliary body 1 | 1
Hypoproteinemia 1 | 8
Imperforate anus 1 | 25
Intellectual disability 1 | 1,016
Lipoma 1 | 32
Liver cancer 1 | 604
Mesangial sclerosis, diffuse 1 | 1
Muscle hypotonia 1 | 571
Myopia 1 | 176
NEPHROTIC SYNDROME, TYPE 5, WITH OR WITHOUT OCULAR ABNORMALITIES 1 | 1
Neonatal onset 1 | 21
Nephrotic Syndrome 1 | 78
Neurodegenerative disease 1 | 414
Neurogenic bladder 1 | 16
Neurogenic bowel 1 | 6
Nystagmus 1 | 317
Obesity 1 | 678
Pick's disease 1 | 15
Pierson syndrome 1 | 13
Posterior lenticonus 1 | 1
Prostatic Neoplasms 1 | 495
Proteinuria 1 | 144
Rectal prolapse 1 | 19
Reflex, Deep Tendon, Absent 1 | 92
Rhabdomyosarcoma 1 | 39
Sarcoma 1 | 62
Strabismus 1 | 270
Tethered spinal cord syndrome 1 | 11
Urethral diverticulum 1 | 3
VACTERL association 1 | 26
active ulcerative colitis 1 | 764
acute quadriplegic myopathy 1 | 1,158
adult high grade glioma 1 | 3,801
astrocytic glioma 1 | 2,597
astrocytoma 1 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
cystic fibrosis 1 | 1,696
dermatomyositis 1 | 966
hereditary spastic paraplegia 1 | 318
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
invasive ductal carcinoma 1 | 2,951
juvenile dermatomyositis 1 | 1,187
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
medulloblastoma, large-cell 1 | 6,241
non primary Sjogren syndrome sicca 1 | 891
oligodendroglioma 1 | 2,850
pancreatic cancer 1 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
primary pancreatic ductal adenocarcinoma 1 | 1,109
primitive neuroectodermal tumor 1 | 3,035
progressive supranuclear palsy 1 | 676

Tissue

Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Liver and Pancreas 4 | 16,750
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Non-IDG 3 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634

Compartment GO Term

nucleus-vacuole junction 5 | 5
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Oxysterol-binding protein 1 OSBP Tbio Non-IDG -2.22394 167.6 160
Kinase D-interacting substrate of 220 kDa KIDINS220 Tbio Enzyme -2.42897 262.3 191
Histone H1oo H1FOO Tbio Non-IDG -1.48386 31.5 137
Phosphoinositide 3-kinase regulatory subunit 4 PIK3R4 Tbio Kinase -1.49076 28.7 316
Laminin subunit beta-2 LAMB2 Tbio Non-IDG -2.14401 131.7 230