Development Level

Tbio 30 | 10,625
Tchem 8 | 1,890
Tclin 2 | 602
Tdark 2 | 7,003

IMPC Phenotype

embryonic lethality prior to t... 2 | 187
preweaning lethality, complete... 2 | 633
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal placement of pupils 1 | 4
abnormal retina morphology 1 | 100
abnormal spleen morphology 1 | 36
anophthalmia 1 | 20
cataract 1 | 26
corneal opacity 1 | 25
decreased body weight 1 | 174
embryonic lethality prior to o... 1 | 148
increased bone mineral density 1 | 52
increased circulating potassiu... 1 | 31
increased hemoglobin content 1 | 45
male infertility 1 | 62
narrow eye opening 1 | 15
small testis 1 | 37
thrombocytopenia 1 | 46

Disease

osteosarcoma 29 | 7,933
ovarian cancer 28 | 8,491
Cancer 26 | 2,346
Xeroderma pigmentosum 24 | 41
Cockayne syndrome 21 | 54
group 3 medulloblastoma 19 | 2,254
lung cancer 15 | 4,473
malignant mesothelioma 14 | 3,163
medulloblastoma, large-cell 14 | 6,234
psoriasis 13 | 6,685
Breast cancer 12 | 3,098
Photosensitive trichothiodystrophy 11 | 24
Carcinoma 10 | 2,147
Prostatic Neoplasms 9 | 471
Stomach Neoplasms 9 | 282
atypical teratoid / rhabdoid tumor 9 | 4,369
primitive neuroectodermal tumor 9 | 3,031
glioblastoma 8 | 5,572
Colorectal Neoplasms 7 | 217
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
lung adenocarcinoma 7 | 2,714
Bloom syndrome 6 | 30
Lynch syndrome 6 | 35
Micronuclei, Chromosome-Defective 6 | 20
non-small cell lung cancer 6 | 2,798
pediatric high grade glioma 6 | 2,712
pilocytic astrocytoma 6 | 3,086
Familial adenomatous polyposis 5 | 33
Fanconi's anemia 5 | 50
Peripheral Neuropathy 5 | 303
Waldenstrons macroglobulinemia 5 | 764
diabetes mellitus 5 | 1,663
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
invasive ductal carcinoma 5 | 2,950
nasopharyngeal carcinoma 5 | 1,056
oligodendroglioma 5 | 2,849
pancreatic cancer 5 | 2,300
tuberculosis 5 | 1,563
Adenocarcinoma of lung (disorder) 4 | 48
Adenoma 4 | 165
Arsenic Poisoning 4 | 59
Bladder Neoplasm 4 | 109
CAMFAK syndrome 4 | 4
COFS syndrome 4 | 4
Cerebrooculofacioskeletal Syndrome 1 4 | 4
Endometrial cancer 4 | 32
Lung Neoplasms 4 | 171
Melanoma 4 | 261
Neoplasm Metastasis 4 | 138
Pena Shokeir syndrome Type 2 4 | 4
Skin Neoplasms 4 | 49
Xeroderma pigmentosum-Cockayne syndrome complex 4 | 4
acute myeloid leukemia 4 | 785
adrenocortical carcinoma 4 | 1,427
dermatomyositis 4 | 966
ductal carcinoma in situ 4 | 1,745
hepatocellular carcinoma 4 | 550
pancreatic carcinoma 4 | 567
pituitary cancer 4 | 1,972
sonic hedgehog group medulloblastoma 4 | 1,482
tuberculosis and treatment for 6 months 4 | 686
Anemia 3 | 252
Basal cell carcinoma 3 | 31
Cataract 3 | 104
Cerebro-oculo-facio-skeletal syndrome 3 | 3
Chromosome Aberrations 3 | 15
Cockayne Syndrome, Type I 3 | 3
Cockayne Syndrome, Type II 3 | 3
Disease Progression 3 | 125
Fanconi Anemia 3 | 22
Male infertility 3 | 170
Mammary Neoplasms 3 | 410
Multiple myeloma 3 | 1,327
Neoplastic Syndromes, Hereditary 3 | 48
Skin benign neoplasm 3 | 5
Trichothiodystrophy 1, photosensitive 3 | 4
Trichothiodystrophy Syndromes 3 | 5
UV-sensitive syndrome 3 | 7
Werner syndrome 3 | 29
acute quadriplegic myopathy 3 | 1,157
astrocytic glioma 3 | 2,241
astrocytoma 3 | 1,493
ovarian neoplasm 3 | 97
posterior fossa group A ependymoma 3 | 1,511
subependymal giant cell astrocytoma 3 | 2,287
Amyotrophic Lateral Sclerosis 2 | 432
Craniofacial Abnormalities 2 | 147
Dermatologic disorders 2 | 65
Liver carcinoma 2 | 217
Lymphoma 2 | 57
Mammary Neoplasms, Experimental 2 | 149
Mesothelioma 2 | 40
Microcephaly 2 | 149
Neurodegenerative disease 2 | 383
Pancreatic Neoplasm 2 | 79
Seckel syndrome 2 | 35
Squamous cell carcinoma 2 | 96
Squamous cell carcinoma of esophagus 2 | 82
atypical teratoid/rhabdoid tumor 2 | 1,095
glioblastoma multiforme 2 | 347

Tissue

Blood and immune system 42 | 17,994
Cardiovascular System 42 | 17,957
Digestive Tract 42 | 18,472
Endocrine System 42 | 18,511
Female tissues 42 | 18,646
Liver and Pancreas 42 | 18,135
Male tissues 42 | 17,968
Nervous System 42 | 18,560
Respiratory system 42 | 17,483
Skin and soft tissues 42 | 18,114
Urinary Tract 42 | 18,443

Target Family

Non-IDG 23 | 11,969
Enzyme 18 | 4,146
Transcription Factor 1 | 1,400

Compartment GO Term

nucleotide-excision repair com... 42 | 42
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA repair protein XRCC3 XRCC3 Tbio Non-IDG -2.49911 286.4 377
DNA repair protein complementing XP-C cells XPC Tbio Non-IDG -2.18675 151.0 193
Flap endonuclease 1 FEN1 Tchem Enzyme -2.77484 533.8 332
DNA repair protein complementing XP-G cells ERCC5 Tchem Enzyme -2.05009 296.8 215
MMS19 nucleotide excision repair protein homolog MMS19 Tbio Non-IDG -1.63430 40.6 112
General transcription factor IIH subunit 1 GTF2H1 Tbio Non-IDG -1.64263 41.9 218
DNA polymerase epsilon subunit 3 POLE3 Tbio Enzyme -0.73319 5.86 173
DNA excision repair protein ERCC-1 ERCC1 Tbio Non-IDG -3.01167 969.9 606
Chromatin accessibility complex protein 1 CHRAC1 Tdark Non-IDG -0.47787 3.02 104
DNA polymerase epsilon subunit 4 POLE4 Tdark Enzyme -0.36530 2.18 29