Development Level
Tbio | 2,587 | 10,625 | |
Tdark | 661 | 7,003 | |
Tchem | 467 | 1,890 | |
Tclin | 124 | 602 |
Collection
Eligible Kinase Proteins | 19 | 134 | |
Eligible Ion Channel Proteins | 6 | 117 | |
Eligible non-olfactory GPCR Proteins | 2 | 145 |
IMPC Term
preweaning lethality, complete... | 216 | 633 | |
preweaning lethality, incomple... | 82 | 260 | |
embryonic lethality prior to t... | 66 | 187 | |
embryonic lethality prior to o... | 56 | 148 | |
abnormal behavior | 53 | 226 | |
decreased body weight | 53 | 174 | |
decreased total body fat amoun... | 50 | 186 | |
decreased lean body mass | 49 | 195 | |
decreased bone mineral content | 42 | 157 | |
abnormal embryo size | 39 | 112 | |
decreased body length | 36 | 108 | |
decreased bone mineral density | 36 | 126 | |
increased or absent threshold ... | 36 | 128 | |
decreased grip strength | 33 | 123 | |
abnormal bone structure | 32 | 131 | |
hyperactivity | 31 | 108 | |
decreased circulating glucose ... | 29 | 121 | |
increased circulating alkaline... | 29 | 119 | |
increased lean body mass | 29 | 107 | |
abnormal retina morphology | 27 | 100 | |
decreased circulating choleste... | 26 | 85 | |
increased mean corpuscular hem... | 25 | 93 | |
increased mean corpuscular vol... | 25 | 91 | |
increased grip strength | 24 | 83 | |
decreased circulating HDL chol... | 23 | 77 | |
abnormal lens morphology | 22 | 73 | |
increased bone mineral content | 22 | 92 | |
male infertility | 20 | 62 | |
improved glucose tolerance | 18 | 56 | |
increased circulating HDL chol... | 18 | 63 | |
increased circulating chloride... | 18 | 43 | |
decreased circulating serum al... | 17 | 79 | |
decreased lumbar vertebrae num... | 17 | 62 | |
enlarged heart | 17 | 111 | |
increased fasted circulating g... | 17 | 68 | |
increased sacral vertebrae num... | 17 | 62 | |
prenatal lethality prior to he... | 17 | 64 | |
short tibia | 17 | 82 | |
abnormal coat/hair pigmentatio... | 16 | 54 | |
abnormal sleep behavior | 16 | 63 | |
decreased mean corpuscular vol... | 16 | 50 | |
increased circulating choleste... | 16 | 53 | |
abnormal bone mineralization | 14 | 55 | |
decreased circulating alanine ... | 14 | 53 | |
decreased circulating triglyce... | 14 | 83 | |
increased blood urea nitrogen ... | 14 | 44 | |
hypoactivity | 13 | 89 | |
increased body weight | 13 | 42 | |
increased bone mineral density | 13 | 52 | |
increased circulating sodium l... | 13 | 71 | |
increased heart weight | 13 | 37 | |
thrombocytopenia | 13 | 46 | |
abnormal behavioral response t... | 12 | 52 | |
abnormal retinal pigmentation | 12 | 61 | |
decreased caudal vertebrae num... | 12 | 49 | |
decreased fasted circulating g... | 12 | 49 | |
decreased heart weight | 12 | 44 | |
decreased startle reflex | 12 | 48 | |
increased exploration in new e... | 12 | 56 | |
abnormal gait | 11 | 51 | |
decreased circulating LDL chol... | 11 | 37 | |
decreased circulating free fat... | 11 | 39 | |
decreased circulating insulin ... | 11 | 75 | |
decreased rib number | 11 | 59 | |
embryonic growth retardation | 11 | 28 | |
increased rib number | 11 | 41 | |
abnormal cornea morphology | 10 | 24 | |
abnormal limb bud morphology | 10 | 15 | |
abnormal neural tube closure | 10 | 37 | |
abnormal spleen morphology | 10 | 36 | |
cardiovascular system phenotyp... | 10 | 35 | |
cataract | 10 | 26 | |
decreased eosinophil cell numb... | 10 | 41 | |
decreased leukocyte cell numbe... | 10 | 54 | |
decreased prepulse inhibition | 10 | 52 | |
female infertility | 10 | 34 | |
increased hemoglobin content | 10 | 45 | |
increased startle reflex | 10 | 38 | |
decreased blood urea nitrogen ... | 9 | 31 | |
decreased circulating aspartat... | 9 | 27 | |
decreased circulating iron lev... | 9 | 25 | |
decreased hemoglobin content | 9 | 53 | |
decreased mean corpuscular hem... | 9 | 34 | |
hydrops fetalis | 9 | 22 | |
impaired glucose tolerance | 9 | 52 | |
increased circulating iron lev... | 9 | 25 | |
increased circulating triglyce... | 9 | 24 | |
increased leukocyte cell numbe... | 9 | 37 | |
increased mean corpuscular hem... | 9 | 25 | |
increased total body fat amoun... | 9 | 57 | |
limb grasping | 9 | 35 | |
polydactyly | 9 | 22 | |
abnormal coat appearance | 8 | 25 | |
decreased circulating alkaline... | 8 | 41 | |
decreased circulating total pr... | 8 | 41 | |
increased circulating serum al... | 8 | 25 | |
increased hematocrit | 8 | 36 | |
shortened RR interval | 8 | 19 | |
small testis | 8 | 37 | |
tremors | 8 | 34 |
Disease
Tissue
Female tissues | 3,790 | 18,647 | |
Nervous System | 3,780 | 18,561 | |
Endocrine System | 3,771 | 18,512 | |
Digestive Tract | 3,768 | 18,473 | |
Urinary Tract | 3,757 | 18,444 | |
Male tissues | 3,755 | 17,969 | |
Liver and Pancreas | 3,752 | 18,136 | |
Blood and immune system | 3,744 | 17,995 | |
Cardiovascular System | 3,743 | 17,958 | |
Skin and soft tissues | 3,722 | 18,115 | |
Respiratory system | 3,699 | 17,484 |
Target Family
Non-IDG | 2,555 | 11,969 | |
Enzyme | 676 | 4,146 | |
Transcription Factor | 235 | 1,400 | |
Kinase | 165 | 634 | |
Epigenetic | 106 | 242 | |
Ion Channel | 32 | 341 | |
Transporter | 22 | 473 | |
Nuclear Receptor | 19 | 48 | |
TF/Epigenetic | 15 | 38 | |
GPCR | 13 | 408 | |
oGPCR | 1 | 421 |
Compartment GO Term
non-membrane-bounded organelle | 3,839 | 3,839 | |
cellular_component | 18,238 | 18,238 | |
Cell | 15,807 | 15,807 | |
Cell part | 15,807 | 15,807 | |
Intracellular | 13,612 | 13,612 | |
Intracellular part | 13,475 | 13,475 | |
Organelle | 12,649 | 12,649 | |
membrane-bounded organelle | 11,794 | 11,794 | |
Intracellular organelle | 11,618 | 11,618 | |
Intracellular membrane-bounded... | 10,619 | 10,619 | |
Cytoplasm | 10,353 | 10,353 | |
Membrane | 8,871 | 8,871 | |
Organelle part | 8,169 | 8,169 | |
Intracellular organelle part | 8,012 | 8,012 | |
Cytoplasmic part | 7,831 | 7,831 | |
Nucleus | 7,577 | 7,577 | |
Membrane part | 6,469 | 6,469 | |
Cytosol | 6,034 | 6,034 | |
Plasma membrane | 5,673 | 5,673 | |
Intrinsic component of membran... | 5,445 | 5,445 | |
Integral component of membrane | 5,315 | 5,315 | |
Macromolecular complex | 5,171 | 5,171 | |
Cell periphery | 5,146 | 5,146 | |
Nucleoplasm | 4,930 | 4,930 | |
Extracellular region | 4,607 | 4,607 | |
Protein complex | 4,439 | 4,439 | |
Intracellular organelle lumen | 4,331 | 4,331 | |
Organelle lumen | 4,331 | 4,331 | |
membrane-enclosed lumen | 4,331 | 4,331 | |
Extracellular region part | 3,874 | 3,874 | |
Intracellular non-membrane-bou... | 3,840 | 3,840 | |
Nuclear part | 3,808 | 3,808 | |
Endomembrane system | 3,720 | 3,720 | |
Vesicle | 3,667 | 3,667 | |
membrane-bounded vesicle | 3,495 | 3,495 | |
Nuclear lumen | 3,465 | 3,465 | |
Extracellular organelle | 2,850 | 2,850 | |
Extracellular vesicle | 2,849 | 2,849 | |
Extracellular exosome | 2,829 | 2,829 | |
Organelle membrane | 2,592 | 2,592 | |
Plasma membrane part | 2,564 | 2,564 | |
Cytoskeleton | 2,046 | 2,046 | |
Golgi apparatus | 1,946 | 1,946 | |
Endoplasmic reticulum | 1,872 | 1,872 | |
Intrinsic component of plasma ... | 1,783 | 1,783 | |
Bounding membrane of organelle | 1,729 | 1,729 | |
Integral component of plasma m... | 1,723 | 1,723 | |
Vesicles | 1,625 | 1,625 | |
Cytoskeletal part | 1,568 | 1,568 | |
Mitochondrion | 1,530 | 1,530 | |
Cell projection | 1,425 | 1,425 | |
Extracellular space | 1,329 | 1,329 | |
Whole membrane | 1,320 | 1,320 | |
GO:0098796 | 1,304 | 1,304 | |
Cell junction | 1,301 | 1,301 | |
Vacuole | 1,263 | 1,263 | |
Intracellular vesicle | 1,256 | 1,256 | |
Cytoplasmic vesicle | 1,255 | 1,255 | |
Catalytic complex | 1,234 | 1,234 | |
Endoplasmic reticulum part | 1,230 | 1,230 | |
cytoplasmic, membrane-bounded ... | 1,125 | 1,125 | |
GO:0031975 | 1,092 | 1,092 | |
Microtubule cytoskeleton | 1,087 | 1,087 | |
Organelle envelope | 1,084 | 1,084 | |
Nuclear outer membrane-endopla... | 1,079 | 1,079 | |
Endoplasmic reticulum membrane | 1,062 | 1,062 | |
Mitochondria | 1,003 | 1,003 | |
Chromosome | 999 | 999 | |
Mitochondrial part | 988 | 988 | |
Nucleoli | 950 | 950 | |
Golgi apparatus part | 940 | 940 | |
Neuron part | 913 | 913 | |
Chromosomal part | 862 | 862 | |
Endosome | 857 | 857 | |
Nucleolus | 839 | 839 | |
Cell surface | 836 | 836 | |
Transferase complex | 815 | 815 | |
Ribonucleoprotein complex | 794 | 794 | |
Intracellular ribonucleoprotei... | 790 | 790 | |
Nucleoplasm part | 781 | 781 | |
Plasma membrane region | 777 | 777 | |
Vacuolar part | 776 | 776 | |
Polymeric cytoskeletal fiber | 758 | 758 | |
Supramolecular fiber | 758 | 758 | |
Cell projection part | 739 | 739 | |
Plasma membrane protein comple... | 721 | 721 | |
Mitochondrial envelope | 716 | 716 | |
Golgi membrane | 710 | 710 | |
Anchoring junction | 702 | 702 | |
Adherens junction | 687 | 687 | |
Cytoplasmic vesicle part | 682 | 682 | |
Neuron projection | 681 | 681 | |
Microtubule organizing center | 680 | 680 | |
Centrosome | 676 | 676 | |
Vacuolar membrane | 667 | 667 | |
Mitochondrial membrane | 663 | 663 | |
Receptor complex | 656 | 656 | |
Extracellular matrix | 633 | 633 | |
Synapse | 594 | 594 | |
Lytic vacuole | 571 | 571 |
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