Development Level

Tbio 2,978 | 10,625
Tdark 620 | 7,003
Tchem 606 | 1,890
Tclin 127 | 602

Collection

Eligible Kinase Proteins 29 | 134
Eligible non-olfactory GPCR Proteins 3 | 143

IMPC Term

preweaning lethality, complete... 264 | 633
embryonic lethality prior to o... 76 | 148
embryonic lethality prior to t... 76 | 187
preweaning lethality, incomple... 75 | 260
abnormal behavior 65 | 226
decreased body weight 57 | 174
decreased total body fat amoun... 55 | 186
decreased lean body mass 52 | 195
abnormal embryo size 45 | 112
decreased body length 40 | 108
abnormal bone structure 38 | 131
increased or absent threshold ... 37 | 128
abnormal retina morphology 36 | 100
decreased bone mineral content 35 | 157
decreased circulating glucose ... 35 | 121
enlarged heart 35 | 111
increased circulating alkaline... 34 | 119
increased lean body mass 34 | 107
decreased grip strength 32 | 123
increased bone mineral content 32 | 92
decreased bone mineral density 31 | 126
hyperactivity 31 | 108
abnormal lens morphology 28 | 73
decreased circulating choleste... 28 | 85
increased grip strength 28 | 83
decreased circulating HDL chol... 27 | 77
increased mean corpuscular hem... 26 | 93
increased mean corpuscular vol... 26 | 91
prenatal lethality prior to he... 26 | 64
short tibia 24 | 82
abnormal bone mineralization 22 | 55
decreased circulating serum al... 22 | 79
decreased circulating triglyce... 22 | 83
decreased hemoglobin content 21 | 53
increased sacral vertebrae num... 21 | 62
abnormal retinal pigmentation 20 | 61
decreased lumbar vertebrae num... 20 | 62
abnormal coat/hair pigmentatio... 19 | 54
decreased circulating insulin ... 19 | 75
decreased leukocyte cell numbe... 19 | 54
decreased rib number 19 | 59
hypoactivity 19 | 89
increased bone mineral density 19 | 52
increased circulating HDL chol... 19 | 63
abnormal heart morphology 18 | 51
decreased caudal vertebrae num... 18 | 49
decreased prepulse inhibition 17 | 52
increased fasted circulating g... 17 | 68
male infertility 17 | 62
decreased erythrocyte cell num... 16 | 43
decreased fasted circulating g... 16 | 49
increased circulating choleste... 16 | 53
decreased circulating LDL chol... 15 | 37
decreased mean corpuscular vol... 15 | 50
embryonic growth retardation 15 | 28
abnormal eye morphology 14 | 38
abnormal gait 14 | 51
impaired glucose tolerance 14 | 52
increased blood urea nitrogen ... 14 | 44
increased circulating sodium l... 14 | 71
abnormal seminal vesicle morph... 13 | 47
decreased heart weight 13 | 44
increased circulating creatini... 13 | 29
thrombocytopenia 13 | 46
abnormal behavioral response t... 12 | 52
abnormal sleep behavior 12 | 63
decreased circulating alanine ... 12 | 53
decreased circulating total pr... 12 | 41
decreased mean corpuscular hem... 12 | 34
decreased startle reflex 12 | 48
increased heart weight 12 | 37
increased hemoglobin content 12 | 45
increased total body fat amoun... 12 | 57
polydactyly 12 | 22
abnormal locomotor activation 11 | 26
abnormal neural tube closure 11 | 37
corneal opacity 11 | 25
decreased T cell number 11 | 31
decreased circulating alkaline... 11 | 41
decreased eosinophil cell numb... 11 | 41
decreased hematocrit 11 | 25
increased circulating triglyce... 11 | 24
increased mean corpuscular hem... 11 | 25
increased startle reflex 11 | 38
abnormal cornea morphology 10 | 24
abnormal kidney morphology 10 | 30
cataract 10 | 26
decreased Ly6C low monocyte nu... 10 | 23
decreased circulating fructosa... 10 | 31
decreased circulating iron lev... 10 | 25
female infertility 10 | 34
hydrops fetalis 10 | 22
improved glucose tolerance 10 | 56
increased exploration in new e... 10 | 56
small testis 10 | 37
tremors 10 | 34
anophthalmia 9 | 20
cardiovascular system phenotyp... 9 | 35
decreased circulating aspartat... 9 | 27
increased circulating chloride... 9 | 43

Disease

ovarian cancer 2,549 | 8,484
osteosarcoma 2,114 | 7,933
psoriasis 1,619 | 6,685
medulloblastoma, large-cell 1,573 | 6,234
glioblastoma 1,420 | 5,572
lung cancer 1,417 | 4,466
atypical teratoid / rhabdoid tumor 1,074 | 4,369
Cancer 940 | 2,346
malignant mesothelioma 933 | 3,162
Breast cancer 879 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 860 | 3,289
primitive neuroectodermal tumor 795 | 3,031
non-small cell lung cancer 733 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 732 | 2,988
group 3 medulloblastoma 726 | 2,254
pediatric high grade glioma 723 | 2,712
invasive ductal carcinoma 713 | 2,950
oligodendroglioma 710 | 2,849
lung adenocarcinoma 677 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 659 | 2,956
ependymoma 626 | 2,514
pilocytic astrocytoma 593 | 3,086
Multiple myeloma 587 | 1,327
pancreatic cancer 568 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 540 | 1,795
Carcinoma 531 | 2,147
subependymal giant cell astrocytoma 516 | 2,287
astrocytic glioma 513 | 2,241
Pick disease 500 | 1,893
diabetes mellitus 468 | 1,663
lung carcinoma 466 | 2,844
ulcerative colitis 464 | 2,087
astrocytoma 455 | 1,493
group 4 medulloblastoma 449 | 1,875
adult high grade glioma 427 | 2,148
pituitary cancer 422 | 1,972
breast carcinoma 420 | 1,614
colon cancer 418 | 1,475
ductal carcinoma in situ 418 | 1,745
interstitial cystitis 404 | 2,299
sonic hedgehog group medulloblastoma 403 | 1,482
acute quadriplegic myopathy 401 | 1,157
adrenocortical carcinoma 390 | 1,427
juvenile dermatomyositis 383 | 1,189
Waldenstrons macroglobulinemia 354 | 765
tuberculosis 354 | 1,557
medulloblastoma 351 | 1,524
posterior fossa group A ependymoma 351 | 1,511
dermatomyositis 344 | 933
Rheumatoid Arthritis 329 | 1,160
primary pancreatic ductal adenocarcinoma 322 | 1,271
cystic fibrosis 319 | 1,665
atypical teratoid/rhabdoid tumor 282 | 1,095
nasopharyngeal carcinoma 276 | 1,056
acute myeloid leukemia 275 | 780
spina bifida 262 | 1,064
non primary Sjogren syndrome sicca 255 | 840
posterior fossa group B ependymoma 255 | 1,530
Atopic dermatitis 221 | 944
cutaneous lupus erythematosus 221 | 1,056
tuberculosis and treatment for 6 months 208 | 686
gastric carcinoma 203 | 832
Intellectual disability 198 | 573
active Crohn's disease 197 | 918
Alzheimer's disease 193 | 644
progressive supranuclear palsy 192 | 674
Mammary Neoplasms 188 | 410
primary Sjogren syndrome 188 | 789
Endometriosis 185 | 535
aldosterone-producing adenoma 180 | 664
esophageal adenocarcinoma 179 | 737
Prostatic Neoplasms 171 | 471
hepatocellular carcinoma 170 | 532
pancreatic carcinoma 158 | 567
Obesity 157 | 616
Amyotrophic Lateral Sclerosis 152 | 431
Down syndrome 148 | 548
IGA Glomerulonephritis 140 | 454
Neurodegenerative disease 137 | 383
autosomal dominant Emery-Dreifuss muscular dystrophy 134 | 499
Duchenne muscular dystrophy 130 | 602
Stomach Neoplasms 129 | 282
Kidney disease 123 | 396
gastric cancer 123 | 430
inflammatory breast cancer 120 | 404
Polycystic Ovary Syndrome 118 | 332
Vascular disease 112 | 281
fibroadenoma 105 | 557
Parkinson's disease 104 | 364
Schizophrenia 103 | 501
Liver carcinoma 100 | 217
mucosa-associated lymphoid tissue lymphoma 100 | 480
Atherosclerosis 96 | 275
Peripheral Neuropathy 95 | 303
active ulcerative colitis 94 | 477
hereditary spastic paraplegia 94 | 313
non-small cell lung carcinoma 94 | 413
Heart disease 93 | 279
Multiple Sclerosis 91 | 498
chronic rhinosinusitis 90 | 512

Tissue

Female tissues 4,288 | 18,647
Nervous System 4,282 | 18,561
Digestive Tract 4,276 | 18,473
Endocrine System 4,273 | 18,512
Urinary Tract 4,271 | 18,444
Blood and immune system 4,269 | 17,995
Male tissues 4,269 | 17,969
Liver and Pancreas 4,268 | 18,136
Cardiovascular System 4,258 | 17,958
Skin and soft tissues 4,231 | 18,115
Respiratory system 4,223 | 17,484

Target Family

Non-IDG 2,267 | 11,971
Enzyme 1,172 | 4,146
Transcription Factor 434 | 1,400
Kinase 184 | 634
Epigenetic 168 | 242
Nuclear Receptor 46 | 48
TF/Epigenetic 26 | 38
Transporter 22 | 473
GPCR 7 | 406
Ion Channel 5 | 341

Compartment GO Term

membrane-enclosed lumen 4,331 | 4,331
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger and BTB domain-containing protein 1 ZBTB1 Tbio Transcription Factor -0.57513 5.01 57
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Syntaxin-1B STX1B Tbio Non-IDG -1.74488 52.6 27
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
ADP/ATP translocase 1 SLC25A4 Tbio Transporter -2.05462 110.8 89
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Histone deacetylase 5 HDAC5 Tclin Epigenetic -2.11372 127.6 466
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Forkhead box protein M1 FOXM1 Tbio Transcription Factor -3.09305 1275.4 345