Development Level

Tbio 24 | 11,445
Tdark 4 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
decreased bone mineral density 1 | 126
decreased fasted circulating g... 1 | 65
embryonic lethality prior to o... 1 | 239
increased bone mineral density 1 | 72
increased fasted circulating g... 1 | 76
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

Carcinoma 21 | 11,493
ovarian cancer 17 | 8,520
osteosarcoma 14 | 7,950
ependymoma 8 | 4,679
glioblastoma 8 | 5,792
group 3 medulloblastoma 8 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
lung cancer 8 | 4,740
atypical teratoid / rhabdoid tumor 7 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
medulloblastoma, large-cell 7 | 6,241
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
malignant mesothelioma 6 | 3,232
psoriasis 6 | 6,694
subependymal giant cell astrocytoma 6 | 2,287
Astrocytoma, Pilocytic 5 | 3,081
Kidney cancer 5 | 2,613
adult high grade glioma 5 | 3,801
astrocytic glioma 5 | 2,597
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
Breast cancer 4 | 3,578
acute quadriplegic myopathy 4 | 1,158
non-small cell lung cancer 4 | 2,890
aldosterone-producing adenoma 3 | 665
astrocytoma 3 | 1,146
group 4 medulloblastoma 3 | 1,855
invasive ductal carcinoma 3 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Abnormality of the pharynx 2 | 19
Adult onset 2 | 82
Autosomal recessive predisposition 2 | 1,442
Disease Progression 2 | 136
Kidney disease 2 | 430
Male infertility 2 | 206
Pick disease 2 | 1,894
Rheumatoid arthritis 2 | 1,191
Stomach Neoplasms 2 | 300
Thrombocytopenia 2 | 197
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
hepatocellular carcinoma 2 | 547
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
periodontitis 2 | 293
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
sarcoidosis 2 | 370
Abnormal pigmentation 1 | 25
Abnormality of female internal genitalia 1 | 13
Abnormality of the fingernails 1 | 51
Acute Promyelocytic Leukemia 1 | 40
Age related macular degeneration 1 | 72
Amebiasis 1 | 21
Anorectal Malformations 1 | 8
Aplasia/Hypoplasia of the skin 1 | 16
Benign epilepsy with centrotemporal spikes 1 | 13
Bone marrow hypocellularity 1 | 20
Deglutition Disorders 1 | 132
Doyne honeycomb retinal dystrophy 1 | 9
Dyskeratosis congenita 1 | 24
Endomyocardial Fibrosis 1 | 13
Esophageal Stenosis 1 | 15
Gastroparesis 1 | 22
Gilles de la Tourette syndrome 1 | 47
Gingival Diseases 1 | 19
Glomerulonephritis 1 | 46
Hemolytic-Uremic Syndrome 1 | 30
Hyperpigmented macules 1 | 42
Hypodontia 1 | 81
Hypoplastic-absent toenails 1 | 11
Large elongated pulp chamber 1 | 14
Leukokeratosis 1 | 19
Leukoplakia, Oral 1 | 20
Macular degeneration 1 | 65
Mask-like facies 1 | 25
Muscle weakness of limb 1 | 21
Osteochondritis dissecans 1 | 17
Ovarian serous cystadenocarcinoma 1 | 5
Periodontal Diseases 1 | 21
Premature ovarian failure 1 | 65
Pulmonary Fibrosis 1 | 106
Pyelonephritis 1 | 13
Rectal prolapse 1 | 19
Recurrent otitis media 1 | 42
Recurrent sinus disease 1 | 22
Recurrent sinusitis 1 | 22
Rift Valley fever 1 | 14
Rotting teeth 1 | 73
Rough bone trabeculation 1 | 11
Salivary Gland Neoplasms 1 | 46
Skin Ulcer 1 | 48
Sparse scalp hair 1 | 42
Taurodontism 1 | 14
Tracheoesophageal Fistula 1 | 36
Urethral Stricture 1 | 18
hypopigmented skin patch 1 | 59

Tissue

Cardiovascular System 28 | 15,192
Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Respiratory system 28 | 16,393
Skin and soft tissues 28 | 17,230
Blood and immune system 27 | 16,909
Nervous System 27 | 16,725
Urinary Tract 27 | 16,678

Target Family

Non-IDG 25 | 12,091
Enzyme 3 | 4,145

Compartment GO Term

mRNA cleavage and polyadenylat... 28 | 28
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cleavage and polyadenylation specificity factor subunit 3 CPSF3 Tbio Non-IDG -1.47182 27.3 190
Integrator complex subunit 9 INTS9 Tbio Non-IDG -0.76467 5.03 82
Polyadenylate-binding protein 2 PABPN1 Tbio Non-IDG -2.48757 316.4 120
Cleavage and polyadenylation specificity factor subunit 1 CPSF1 Tbio Non-IDG -1.00806 8.79 51
Pre-mRNA cleavage complex 2 protein Pcf11 PCF11 Tbio Non-IDG -1.38684 23.0 33
Integrator complex subunit 11 INTS11 Tbio Non-IDG -0.83885 6.42 114
Cleavage stimulation factor subunit 3 CSTF3 Tbio Non-IDG -1.06216 10.1 160
RNA polymerase II subunit A C-terminal domain phosphatase SSU72 SSU72 Tbio Enzyme -1.45153 34.4 60
Symplekin SYMPK Tbio Non-IDG -2.60677 393.4 135
Pre-mRNA 3'-end-processing factor FIP1 FIP1L1 Tbio Non-IDG -2.19130 159.7 110