Development Level

Tbio 24 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal embryo size 2 | 220
embryonic growth retardation 2 | 106
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
abnormal vitreous body morphol... 1 | 10
aorta dilation 1 | 3
cataract 1 | 92
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased lactate dehydrogenas... 1 | 16
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hydrometra 1 | 53
increased grip strength 1 | 41
increased heart weight 1 | 62
increased or absent threshold ... 1 | 101
thin ventricular wall 1 | 24

Disease

Carcinoma 17 | 11,493
ovarian cancer 15 | 8,520
medulloblastoma, large-cell 12 | 6,241
osteosarcoma 10 | 7,950
atypical teratoid / rhabdoid tumor 9 | 5,112
glioblastoma 9 | 5,792
lung cancer 9 | 4,740
Cancer 8 | 2,499
psoriasis 8 | 6,694
acute quadriplegic myopathy 7 | 1,158
primitive neuroectodermal tumor 7 | 3,035
astrocytic glioma 6 | 2,597
ependymoma 6 | 4,679
non-small cell lung cancer 6 | 2,890
oligodendroglioma 6 | 2,850
tuberculosis 6 | 2,010
Breast cancer 5 | 3,578
Waldenstrons macroglobulinemia 5 | 765
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287
Amyotrophic lateral sclerosis 4 | 451
Intellectual disability 4 | 1,016
Kidney cancer 4 | 2,613
adult high grade glioma 4 | 3,801
astrocytoma 4 | 1,146
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
juvenile dermatomyositis 4 | 1,187
Astrocytoma, Pilocytic 3 | 3,081
Autistic Disorder 3 | 364
Down syndrome 3 | 499
Duchenne muscular dystrophy 3 | 601
Fragile X-associated tremor/ataxia syndrome 3 | 6
Multiple myeloma 3 | 1,332
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
medulloblastoma 3 | 720
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Cognitive delay 2 | 608
Enophthalmos 2 | 75
Fragile X syndrome 2 | 34
Global developmental delay 2 | 608
HIV Infections 2 | 102
Joint laxity 2 | 54
Lymphoma, Mantle-Cell 2 | 11
Major Depressive Disorder 2 | 301
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse 2 | 12
Mental and motor retardation 2 | 608
Muscle hypotonia 2 | 571
Neurodegenerative disease 2 | 414
Premature ovarian failure 2 | 65
Primary biliary cirrhosis 2 | 51
Retinitis pigmentosa 29 2 | 6
Sunken eyes 2 | 63
Unipolar Depression 2 | 250
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
gastric carcinoma 2 | 807
pediatric high grade glioma 2 | 1,064
posterior fossa group A ependymoma 2 | 468
primary pancreatic ductal adenocarcinoma 2 | 1,109
sarcoidosis 2 | 370
ulcerative colitis 2 | 1,819
Acquired flat foot 1 | 72
Amenorrhea 1 | 58
Amnestic disorder 1 | 35
Cerebellar Dysmetria 1 | 56
Corneal edema 1 | 14
Elevated gonadotropins 1 | 15
Flatfoot 1 | 73
Gonadal Dysgenesis 1 | 28
Human granulocytic anaplasmosis 1 | 7
Mask-like facies 1 | 25
Mitral Valve Prolapse Syndrome 1 | 39
Mood instability 1 | 2
Muscle Rigidity 1 | 49
Narrow face 1 | 54
Obsessive compulsive behavior 1 | 25
Ovarian Failure, Premature 1 | 9
Ovarian dysfunction 1 | 18
Periventricular neuronal heterotopia 1 | 6
Poor eye contact 1 | 12
Precancerous Conditions 1 | 80
Premature Menopause 1 | 31
Premature ovarian failure 1 1 | 2
Resting Tremor 1 | 9
Sparse body hair 1 | 32
Spinocerebellar ataxia type 2 1 | 23
Thin face 1 | 54

Tissue

Endocrine System 27 | 18,159
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Blood and immune system 26 | 16,909
Cardiovascular System 26 | 15,192
Digestive Tract 26 | 17,369
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678

Target Family

Non-IDG 22 | 12,091
Enzyme 4 | 4,145
Epigenetic 1 | 242

Compartment GO Term

mRNA cap binding complex 27 | 27
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RNMT-activating mini protein FAM103A1 Tbio Non-IDG -0.24304 0.91 14
Eukaryotic translation initiation factor 4E-binding protein 2 EIF4EBP2 Tbio Non-IDG -1.55776 33.4 189
U6 snRNA-associated Sm-like protein LSm1 LSM1 Tbio Non-IDG -2.01162 106.0 191
Neuroguidin NGDN Tbio Non-IDG -2.22456 133.1 93
Enhancer of mRNA-decapping protein 4 EDC4 Tbio Non-IDG -2.26552 178.5 97
Eukaryotic translation initiation factor 4E type 1B EIF4E1B Tdark Non-IDG -0.56319 3.72 25
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 CMTR1 Tbio Enzyme -0.58358 4.31 44
m7GpppX diphosphatase DCPS Tbio Enzyme -2.57336 366.1 161
Nuclear cap-binding protein subunit 1 NCBP1 Tbio Non-IDG -2.34134 207.7 172
mRNA cap guanine-N7 methyltransferase RNMT Tbio Enzyme -1.92856 70.6 309