Development Level

Tbio 16 | 11,445
Tchem 6 | 1,598

IMPC Phenotype

abnormal QT variability 1 | 10
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal skin morphology 1 | 50
abnormal tooth morphology 1 | 24
cataract 1 | 92
decreased circulating sodium l... 1 | 22
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to t... 1 | 278
increased circulating alkaline... 1 | 122
increased erythrocyte cell num... 1 | 39
increased red blood cell distr... 1 | 34
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 18 | 11,493
Autosomal recessive predisposition 16 | 1,442
Breast cancer 14 | 3,578
malignant mesothelioma 14 | 3,232
psoriasis 14 | 6,694
Cancer 13 | 2,499
Epidermolysis bullosa 13 | 21
non-small cell lung cancer 13 | 2,890
glioblastoma 12 | 5,792
pancreatic cancer 12 | 2,398
ependymoma 11 | 4,679
interstitial cystitis 11 | 2,312
osteosarcoma 11 | 7,950
Atrophic scar 10 | 18
Dental caries 10 | 164
Dystrophia unguium 10 | 53
Kidney cancer 10 | 2,613
Milium Cyst 10 | 16
lung cancer 10 | 4,740
lung carcinoma 10 | 2,843
ovarian cancer 10 | 8,520
Anemia 9 | 365
Dental Enamel Hypoplasia 9 | 43
Nail dysplasia 9 | 52
Rotting teeth 9 | 73
esophageal adenocarcinoma 9 | 737
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
lung adenocarcinoma 9 | 2,716
Abnormal blistering of the skin 8 | 54
Aplasia Cutis Congenita 8 | 14
Blister of skin 8 | 54
Congenital scar 8 | 13
Defective enamel matrix 8 | 35
Dysplasia of tooth enamel 8 | 35
Hemoglobin low 8 | 124
Oral mucosal blistering 8 | 10
Prenatal onset 8 | 139
Scarring alopecia of scalp 8 | 13
Skin bulla 8 | 54
Thin dental enamel 8 | 35
atypical teratoid / rhabdoid tumor 8 | 5,112
breast carcinoma 8 | 1,638
cystic fibrosis 8 | 1,696
ANONYCHIA 7 | 20
Astrocytoma, Pilocytic 7 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
invasive ductal carcinoma 7 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Death in early childhood 6 | 82
Death in infancy 6 | 82
Failure to gain weight 6 | 365
Fragile nails 6 | 16
Junctional split 6 | 6
Pediatric failure to thrive 6 | 365
Plantar hyperkeratosis 6 | 7
Skin Erosion 6 | 12
cutaneous lupus erythematosus 6 | 1,057
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
Abnormal pigmentation 5 | 25
Adult junctional epidermolysis bullosa (disorder) 5 | 5
Arthritis 5 | 290
Breast Neoplasms 5 | 445
Bullous pemphigoid 5 | 18
Dehydration 5 | 40
Ectropion 5 | 38
Epidermolysis Bullosa, Junctional, Non-Herlitz Type 5 | 5
Esophageal Stenosis 5 | 15
Flexion contracture of proximal interphalangeal joint 5 | 75
Fragile skin 5 | 18
Hypodontia 5 | 81
Junctional epidermolysis bullosa 5 | 7
Mammary Neoplasms 5 | 425
Osteoporosis 5 | 363
Palmar hyperhidrosis 5 | 5
Sparse body hair 5 | 32
adult high grade glioma 5 | 3,801
astrocytic glioma 5 | 2,597
medulloblastoma, large-cell 5 | 6,241
nasopharyngeal carcinoma 5 | 1,058
oligodendroglioma 5 | 2,850
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Arthrogryposis 4 | 54
Constipation 4 | 181
Contracture 4 | 96
Contracture of joint 4 | 93
Duchenne muscular dystrophy 4 | 601
Flexion contracture 4 | 93
Flexion contractures of joints 4 | 93
Heart disease 4 | 306
Hypertension 4 | 396
Liver cancer 4 | 604
Microstomia 4 | 78
active Crohn's disease 4 | 922
active ulcerative colitis 4 | 764
dermatomyositis 4 | 966
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
pediatric high grade glioma 4 | 1,064
subependymal giant cell astrocytoma 4 | 2,287

Tissue

Blood and immune system 22 | 16,909
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Liver and Pancreas 21 | 16,750
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 15 | 12,091
Enzyme 6 | 4,145
Transcription Factor 1 | 1,400

Compartment GO Term

laminin-5 complex 22 | 22
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Collagen alpha-1(XVII) chain COL17A1 Tbio Non-IDG -2.75473 576.3 123
Tryptophan--tRNA ligase, cytoplasmic WARS Tbio Enzyme -2.74520 518.6 163
CD151 antigen CD151 Tbio Non-IDG -2.40013 244.5 420
Nidogen-1 NID1 Tbio Non-IDG -2.80605 647.4 267
Keratin, type I cytoskeletal 14 KRT14 Tbio Non-IDG -2.90790 721.6 780
Class E basic helix-loop-helix protein 22 BHLHE22 Tbio Transcription Factor -3.02886 950.7 108
Dystonin DST Tbio Non-IDG -2.73231 506.0 127
Plectin PLEC Tbio Non-IDG -2.50749 337.2 130
Integrin beta-4 ITGB4 Tbio Non-IDG -2.26591 177.4 704
Integrin alpha-3 ITGA3 Tchem Non-IDG -2.08360 104.1 587