Development Level

Tbio 7 | 11,445

IMPC Phenotype

impaired glucose tolerance 2 | 75
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased large unstained cell... 1 | 5
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 7 | 11,493
Kidney cancer 6 | 2,613
Kidney disease 4 | 430
Pierson syndrome 4 | 13
astrocytoma 4 | 1,146
atypical teratoid / rhabdoid tumor 4 | 5,112
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
malignant mesothelioma 4 | 3,232
ovarian cancer 4 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
psoriasis 4 | 6,694
Alport syndrome 3 | 21
Astrocytoma, Pilocytic 3 | 3,081
Liver cancer 3 | 604
invasive ductal carcinoma 3 | 2,951
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
Breast cancer 2 | 3,578
Chronic kidney disease stage 5 2 | 31
Duchenne muscular dystrophy 2 | 601
Endometrial cancer 2 | 311
Melanoma 2 | 711
Myopia 2 | 176
Nephrotic Syndrome 2 | 78
Pick disease 2 | 1,894
Prostatic Neoplasms 2 | 495
Proteinuria 2 | 144
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
fibroadenoma 2 | 559
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Absent reflex 1 | 92
Absent tendon reflex 1 | 92
Age related macular degeneration 1 | 72
Age related macular degeneration 1 1 | 4
Blind Vision 1 | 111
Blindness, Legal 1 | 110
Cholestasis 1 | 155
Congenital Bilateral Cataracts 1 | 50
Congenital Myasthenic Syndromes, Postsynaptic 1 | 11
Congenital cataract 1 | 50
Congenital myasthenic syndrome 1 | 25
Decreased platelet count 1 | 111
Edema 1 | 81
Epidermolysis bullosa 1 | 21
Fuchs' endothelial dystrophy 1 | 24
Galloway-Mowat syndrome 1 | 15
Goodpasture syndrome 1 | 6
Hemolytic-Uremic Syndrome 1 | 30
Hirschsprung's disease 1 | 46
Hypoparathyroidism 1 | 41
Ichthyoses 1 | 41
Lambert-Eaton myasthenic syndrome 1 | 12
Leiomyoma 1 | 32
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Liver Cirrhosis, Experimental 1 | 769
Microscopic hematuria 1 | 9
Multiple Sclerosis 1 | 540
Myopathy 1 | 185
Neonatal onset 1 | 21
Nephritis 1 | 51
Polycystic ovary syndrome 1 | 360
Posterior polymorphous corneal dystrophy 1 | 19
Progressive disorder 1 | 142
Reflex, Deep Tendon, Absent 1 | 92
Sensorineural Hearing Loss (disorder) 1 | 284
Sensorineural hearing loss 1 | 106
Skin cancer 1 | 469
Spina bifida occulta 1 | 19
Strabismus 1 | 270
Thickening of glomerular basement membrane 1 | 7
Thrombocytopenia 1 | 197
Weight Gain 1 | 100
X-linked dominant 1 | 57
active Crohn's disease 1 | 922
adrenocortical adenoma 1 | 131
glioblastoma multiforme 1 | 142
inflammatory breast cancer 1 | 286
medulloblastoma 1 | 720
tuberculosis 1 | 2,010

Tissue

Endocrine System 7 | 18,159
Liver and Pancreas 7 | 16,750
Urinary Tract 7 | 16,678
Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Female tissues 6 | 17,400
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230

Target Family

Non-IDG 7 | 12,091

Compartment GO Term

laminin-11 complex 7 | 7
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Laminin subunit gamma-1 LAMC1 Tbio Non-IDG -1.79184 56.7 318
Nidogen-1 NID1 Tbio Non-IDG -2.80605 647.4 267
Complement factor H-related protein 5 CFHR5 Tbio Non-IDG -1.46067 30.5 146
Laminin subunit alpha-5 LAMA5 Tbio Non-IDG -1.43472 26.4 217
Agrin AGRN Tbio Non-IDG -2.73844 569.8 122
Laminin subunit beta-2 LAMB2 Tbio Non-IDG -2.14401 131.7 230
Collagen alpha-5(IV) chain COL4A5 Tbio Non-IDG -2.44387 275.7 90