Development Level

Tbio 24 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal embryo size 2 | 220
cataract 2 | 92
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
decreased cardiac output 1 | 3
decreased cardiac stroke volum... 1 | 6
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
prenatal lethality prior to he... 1 | 87

Disease

ovarian cancer 16 | 8,520
osteosarcoma 14 | 7,950
Carcinoma 9 | 11,493
Friedreich ataxia 8 | 24
lung cancer 8 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
psoriasis 6 | 6,694
Breast cancer 5 | 3,578
Sideroblastic anemia 5 | 20
medulloblastoma, large-cell 5 | 6,241
Autosomal recessive predisposition 4 | 1,442
group 3 medulloblastoma 4 | 4,104
Anemia 3 | 365
Glycine encephalopathy 3 | 29
Lactic acidosis 3 | 51
Multiple Mitochondrial Dysfunctions Syndrome 3 | 3
Multiple myeloma 3 | 1,332
Muscle Weakness 3 | 170
Xeroderma pigmentosum group D 3 | 33
astrocytic glioma 3 | 2,597
tuberculosis 3 | 2,010
Acidosis, Lactic 2 | 97
Action Tremor 2 | 22
Anemia, Sideroblastic 2 | 7
Babinski Reflex 2 | 100
Cerebellar Ataxia 2 | 304
Cerebellar Dysmetria 2 | 56
Combined oxidative phosphorylation deficiency 2 | 14
Dysarthria 2 | 192
Lactic acidemia 2 | 95
Mitochondrial complex I deficiency 2 | 46
Myoglobinuria 2 | 15
Pearson syndrome 2 | 19
Terminal tremor 2 | 20
adrenocortical carcinoma 2 | 1,428
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
Acquired immunodeficiency syndrome 1 | 197
Ampulla of Vater carcinoma 1 | 2
Areflexia of lower limbs 1 | 9
Ataxia 1 | 15
Ataxia, Appendicular 1 | 25
Atransferrinemia 1 | 8
Brucellosis 1 | 24
COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 19 1 | 1
Cardiomegaly 1 | 116
Cerebrotendinous xanthomatosis 1 | 13
Chlamydia 1 | 21
Clonus 1 | 18
Congenital adrenal hyperplasia 1 | 73
Congenital adrenal insufficiency 1 | 7
Congenital bile acid synthesis defect 1 | 15
Corneal edema 1 | 14
Decreased amplitude of sensory action potentials 1 | 2
Decreased mitochondrial complex I activity 1 | 2
Decreased mitochondrial complex III activity 1 | 2
Decreased sensory nerve conduction velocities (NCV) 1 | 8
Dysdiadochokinesis 1 | 25
Dyspnea 1 | 76
Endophthalmitis 1 | 12
Gait imbalance 1 | 17
Genital herpes 1 | 10
Hemochromatosis 1 | 54
Hyperferritinaemia 1 | 14
Idiopathic pulmonary arterial hypertension 1 | 40
Increased ferritin 1 | 14
Increased intramyocellular lipid droplets 1 | 13
Microcytic hypochromic anemia (disorder) 1 | 10
Mitochondrial Myopathies 1 | 21
Mitochondrial myopathy 1 | 26
Multiple mitochondrial dysfunctions syndrome 1 1 | 1
Muscle Cramp 1 | 55
Nephroblastoma 1 | 51
Palpitations 1 | 18
Pelvic inflammatory disease 1 | 21
Peripheral sensory axonal neuropathy 1 | 7
Pertussis 1 | 20
Polycythemia 1 | 25
Pulmonary hypertension 1 | 85
Respiratory complex I deficiency 1 | 2
Respiratory complex III deficiency 1 | 2
Rigid spine muscular dystrophy 1 1 | 14
Scoliosis 1 | 44
Scrapie 1 | 17
Sensory axonal neuropathy 1 | 7
Sensory neuropathy 1 | 20
Serum ferritin increased 1 | 14
Spastic Ataxia 1 | 18
Spotted fever 1 | 8
Stomatitis 1 | 21
Tetanus 1 | 68
Visual field defects 1 | 19
X- linked recessive 1 | 110
Xeroderma pigmentosum 1 | 43
alcohol-related neurodevelopmental disorder 1 | 13
infantile cerebellar-retinal degeneration 1 | 3
inflammatory breast cancer 1 | 286

Tissue

Blood and immune system 27 | 16,909
Cardiovascular System 27 | 15,192
Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Urinary Tract 27 | 16,678

Target Family

Non-IDG 22 | 12,091
Enzyme 3 | 4,145
Kinase 1 | 634
Transporter 1 | 473

Compartment GO Term

iron-sulfur cluster assembly c... 27 | 27
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Iron-sulfur cluster assembly 1 homolog, mitochondrial ISCA1 Tbio Non-IDG -1.68100 45.7 44
Cysteine desulfurase, mitochondrial NFS1 Tbio Enzyme -1.70267 46.3 131
LYR motif-containing protein 4 LYRM4 Tbio Non-IDG -1.25062 16.6 69
Cytosolic Fe-S cluster assembly factor NUBP1 NUBP1 Tbio Non-IDG -1.31867 20.0 105
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial NFU1 Tbio Non-IDG -1.85151 72.7 20
Ferredoxin-2, mitochondrial FDX2 Tdark Non-IDG -0.85150 6.83 4
Iron-sulfur cluster co-chaperone protein HscB, mitochondrial HSCB Tbio Non-IDG -1.63830 47.3 42
SURP and G-patch domain-containing protein 2 SUGP2 Tbio Non-IDG 0.12 0.80 118
Cytoplasmic aconitate hydratase ACO1 Tbio Enzyme -2.59601 396.5 350
ATP-binding cassette sub-family B member 7, mitochondrial ABCB7 Tbio Transporter -1.60023 40.7 179