Development Level

Tbio 12 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

increased grip strength 2 | 41
abnormal bone structure 1 | 187
abnormal motor capabilities-co... 1 | 5
abnormal spinal cord morpholog... 1 | 9
decreased B cell number 1 | 5
decreased body weight 1 | 161
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mature B cell number 1 | 7
decreased total retina thickne... 1 | 17
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating alkaline... 1 | 122
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
preweaning lethality, complete... 1 | 979
short tibia 1 | 97

Disease

Carcinoma 12 | 11,493
osteosarcoma 11 | 7,950
ovarian cancer 11 | 8,520
atypical teratoid / rhabdoid tumor 7 | 5,112
medulloblastoma, large-cell 7 | 6,241
glioblastoma 6 | 5,792
interstitial cystitis 6 | 2,312
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
ulcerative colitis 5 | 1,819
Amyotrophic lateral sclerosis 4 | 451
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
Frontotemporal dementia 3 | 51
Kidney cancer 3 | 2,613
Pick disease 3 | 1,894
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
cystic fibrosis 3 | 1,696
ependymoma 3 | 4,679
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
Bipolar Disorder 2 | 666
Familial hemophagocytic lymphohistiocytosis 1 2 | 11
Familial hemophagocytic lymphohistiocytosis 2 2 | 15
Lupus Erythematosus, Systemic 2 | 67
Motor neuron disease 2 | 49
Smith-Magenis syndrome 2 | 29
Systemic lupus erythematosus 2 | 194
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary Sjogren syndrome 2 | 735
primitive neuroectodermal tumor 2 | 3,035
progressive supranuclear palsy 2 | 676
psoriasis 2 | 6,694
sarcoidosis 2 | 370
tuberculosis 2 | 2,010
Alzheimer's disease 1 | 658
Arthritis, Juvenile 1 | 126
Atopic dermatitis 1 | 952
Atrial Fibrillation 1 | 124
Autistic Disorder 1 | 364
Bleeding time prolonged 1 | 31
Celiac disease 1 | 116
Chronic heart failure 1 | 46
Dementia 1 | 175
Diabetic Nephropathies 1 | 37
Disease of mental health 1 | 36
Disseminated intravascular coagulation 1 | 38
Down syndrome 1 | 499
Endometriosis 1 | 540
Epistaxis 1 | 43
Glanzmann's thrombasthenia 1 | 23
Heart conduction disease 1 | 83
Hermansky-Pudlak syndrome 1 | 42
Huntington's disease 1 | 76
Infantile onset 1 | 238
Juvenile arthritis 1 | 126
Kidney disease 1 | 430
Leukemia 1 | 104
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Liver Cirrhosis, Experimental 1 | 769
Liver cancer 1 | 604
Mental Depression 1 | 333
Multiple system atrophy 1 | 29
Neurodegenerative disease 1 | 414
Nonorganic psychosis 1 | 84
Polycystic ovary syndrome 1 | 360
Psychotic Disorders 1 | 151
Schizoaffective Disorder 1 | 55
Stevens-Johnson syndrome 1 | 92
Substance-Related Disorders 1 | 115
Type 2 diabetes mellitus 1 | 272
Waldenstrons macroglobulinemia 1 | 765
acute quadriplegic myopathy 1 | 1,158
aldosterone-producing adenoma 1 | 665
chronic rhinosinusitis 1 | 512
fibroadenoma 1 | 559
hepatocellular carcinoma 1 | 547
medulloblastoma 1 | 720
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
posterior fossa group A ependymoma 1 | 468
posterior fossa group B ependymoma 1 | 416
tuberculosis and treatment for 3 months 1 | 179
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 16 | 16,909
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Cardiovascular System 15 | 15,192

Target Family

Non-IDG 13 | 12,091
Enzyme 3 | 4,145

Compartment GO Term

guanyl-nucleotide exchange fac... 16 | 16
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ankyrin repeat domain-containing protein 27 ANKRD27 Tbio Non-IDG -1.12548 14.6 65
GTPase-activating protein and VPS9 domain-containing protein 1 GAPVD1 Tbio Enzyme -0.69565 4.71 73
RAS guanyl-releasing protein 1 RASGRP1 Tchem Non-IDG -1.99263 105.6 99
Protein very KIND KNDC1 Tdark Non-IDG -0.08517 1.17 53
Guanine nucleotide exchange protein SMCR8 SMCR8 Tbio Non-IDG -0.57883 3.03 21
Ras guanyl-releasing protein 3 RASGRP3 Tchem Non-IDG -1.50862 36.3 186
RAS guanyl-releasing protein 2 RASGRP2 Tbio Non-IDG -1.23693 18.9 108
RAB6A-GEF complex partner protein 1 RIC1 Tbio Non-IDG -1.24586 19.1 10
WD repeat-containing protein 41 WDR41 Tbio Non-IDG -0.28817 1.20 77
cGMP-inhibited 3',5'-cyclic phosphodiesterase B PDE3B Tclin Enzyme -1.88988 77.5 151