Development Level

Tbio 49 | 11,445
Tchem 7 | 1,598
Tclin 3 | 613
Tdark 2 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

embryonic lethality prior to t... 3 | 278
preweaning lethality, complete... 3 | 979
embryonic lethality prior to o... 2 | 239
impaired glucose tolerance 2 | 75
preweaning lethality, incomple... 2 | 499
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
decreased bone mineral density 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
head bobbing 1 | 5
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating thyroxin... 1 | 7
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
microphthalmia 1 | 26
short tibia 1 | 97
thrombocytopenia 1 | 56

Disease

Carcinoma 45 | 11,493
ovarian cancer 34 | 8,520
osteosarcoma 32 | 7,950
lung carcinoma 24 | 2,843
lung cancer 22 | 4,740
glioblastoma 20 | 5,792
malignant mesothelioma 20 | 3,232
non-small cell lung cancer 20 | 2,890
psoriasis 20 | 6,694
interstitial cystitis 18 | 2,312
Breast cancer 17 | 3,578
lung adenocarcinoma 17 | 2,716
medulloblastoma, large-cell 16 | 6,241
mucosa-associated lymphoid tissue lymphoma 16 | 484
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
subependymal giant cell astrocytoma 14 | 2,287
tuberculosis 14 | 2,010
Cancer 13 | 2,499
ependymoma 13 | 4,679
pancreatic cancer 13 | 2,398
ulcerative colitis 13 | 1,819
Astrocytoma, Pilocytic 12 | 3,081
Kidney cancer 12 | 2,613
group 3 medulloblastoma 12 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
invasive ductal carcinoma 12 | 2,951
adult high grade glioma 11 | 3,801
diabetes mellitus 11 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Autosomal recessive predisposition 9 | 1,442
Melanoma 9 | 711
atypical teratoid / rhabdoid tumor 9 | 5,112
cutaneous lupus erythematosus 9 | 1,057
Rheumatoid arthritis 8 | 1,191
Waldenstrons macroglobulinemia 8 | 765
acute quadriplegic myopathy 8 | 1,158
dermatomyositis 8 | 966
primary pancreatic ductal adenocarcinoma 8 | 1,109
Multiple Sclerosis 7 | 540
Multiple myeloma 7 | 1,332
Skin cancer 7 | 469
head and neck cancer and chronic obstructive pulmonary disease 7 | 239
oligodendroglioma 7 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
spina bifida 7 | 1,074
Down syndrome 6 | 499
Duchenne muscular dystrophy 6 | 601
Liver Cirrhosis, Experimental 6 | 769
astrocytoma 6 | 1,146
breast carcinoma 6 | 1,638
colon cancer 6 | 1,478
gastric carcinoma 6 | 807
group 4 medulloblastoma 6 | 1,855
juvenile dermatomyositis 6 | 1,187
nasopharyngeal carcinoma 6 | 1,058
pediatric high grade glioma 6 | 1,064
primary Sjogren syndrome 6 | 735
Anemia 5 | 365
Atopic dermatitis 5 | 952
chronic lymphosyte leukemia 5 | 204
esophageal adenocarcinoma 5 | 737
primitive neuroectodermal tumor 5 | 3,035
Asthma 4 | 385
Atherosclerosis 4 | 291
Dermatitis 4 | 157
Epilepsy 4 | 792
Kidney disease 4 | 430
Liver cancer 4 | 604
Neurodegenerative disease 4 | 414
Pick disease 4 | 1,894
acute myeloid leukemia 4 | 783
adrenocortical carcinoma 4 | 1,428
astrocytic glioma 4 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
cystic fibrosis 4 | 1,696
hepatocellular carcinoma 4 | 547
non primary Sjogren syndrome sicca 4 | 891
pancreatic carcinoma 4 | 562
periodontitis 4 | 293
Allergic hypersensitivity disease 3 | 126
Alzheimer's disease 3 | 658
Cardiomyopathy 3 | 116
Cardiomyopathy, Dilated 3 | 83
Chronic Lymphocytic Leukemia 3 | 262
Chronic obstructive pulmonary disease 3 | 184
Failure to gain weight 3 | 365
Heart disease 3 | 306
Hypertension 3 | 396
Nail Diseases 3 | 24
Palmoplantar keratosis 3 | 74
Pediatric failure to thrive 3 | 365
Recurrent respiratory infections 3 | 141
Splenomegaly 3 | 190
Wolff-Parkinson-White syndrome 3 | 19
ductal carcinoma in situ 3 | 1,745
gastric cancer 3 | 459
interstitial lung disease 3 | 298
nephrosclerosis 3 | 333
pituitary cancer 3 | 1,972
posterior fossa group A ependymoma 3 | 468

Tissue

Blood and immune system 60 | 16,909
Digestive Tract 60 | 17,369
Skin and soft tissues 60 | 17,230
Endocrine System 59 | 18,159
Female tissues 59 | 17,400
Male tissues 59 | 17,142
Liver and Pancreas 57 | 16,750
Nervous System 57 | 16,725
Respiratory system 57 | 16,393
Urinary Tract 57 | 16,678
Cardiovascular System 54 | 15,192

Target Family

Non-IDG 40 | 12,091
Enzyme 15 | 4,145
GPCR 3 | 408
Transporter 2 | 473
Ion Channel 1 | 344

Compartment GO Term

ficolin-1-rich granule membran... 61 | 61
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.52158 32564.4 32
Transforming protein RhoA RHOA Tbio Enzyme -3.54095 3332.7 501
Galectin-3 LGALS3 Tchem Non-IDG -3.36655 2447.4 1101
Complement receptor type 1 CR1 Tbio Non-IDG -3.36509 2362.6 700
Integrin alpha-X ITGAX Tbio Non-IDG -3.23986 1600.6 1515
Lysosomal alpha-glucosidase GAA Tclin Enzyme -3.09870 1217.4 183
Complement decay-accelerating factor CD55 Tbio Non-IDG -3.05523 1115.2 1004
Desmoplakin DSP Tbio Non-IDG -2.95735 853.9 198
Lysosome-associated membrane glycoprotein 1 LAMP1 Tbio Non-IDG -2.98689 817.3 959
Disintegrin and metalloproteinase domain-containing protein 8 ADAM8 Tchem Enzyme -2.88367 768.4 279