Development Level

Tbio 45 | 11,445
Tdark 4 | 6,588
Tchem 2 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal coat-hair pigmentatio... 1 | 64
abnormal iris pigmentation 1 | 4
abnormal retina morphology 1 | 71
decreased basophil cell number 1 | 16
decreased mean platelet volume 1 | 25
decreased spleen weight 1 | 10
improved glucose tolerance 1 | 79
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
small superior vagus ganglion 1 | 74

Disease

Carcinoma 36 | 11,493
Muscular dystrophy 26 | 75
psoriasis 22 | 6,694
Autosomal recessive predisposition 21 | 1,442
glioblastoma 19 | 5,792
medulloblastoma, large-cell 19 | 6,241
osteosarcoma 19 | 7,950
atypical teratoid / rhabdoid tumor 18 | 5,112
limb-girdle muscular dystrophy 18 | 37
Creatine phosphokinase serum increased 17 | 110
Elevated creatine kinase 17 | 110
Myopathy 17 | 185
ependymoma 17 | 4,679
ovarian cancer 17 | 8,520
Muscle biopsy shows dystrophic changes 16 | 39
Congenital muscular dystrophy 15 | 29
lung carcinoma 14 | 2,843
Kidney cancer 13 | 2,613
Lissencephaly 13 | 69
lung cancer 13 | 4,740
Intellectual disability 12 | 1,016
Muscle hypotonia 12 | 571
Walker-Warburg syndrome 12 | 20
group 3 medulloblastoma 12 | 4,104
invasive ductal carcinoma 12 | 2,951
Breast cancer 11 | 3,578
Duchenne muscular dystrophy 11 | 601
Dull intelligence 11 | 645
Hydrocephalus 11 | 152
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Poor school performance 11 | 645
Walker-Warburg congenital muscular dystrophy 11 | 14
ductal carcinoma in situ 11 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Astrocytoma, Pilocytic 10 | 3,081
acute quadriplegic myopathy 10 | 1,158
adult high grade glioma 10 | 3,801
breast carcinoma 10 | 1,638
Cardiomyopathy 9 | 116
Myopia 9 | 176
colon cancer 9 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
lung adenocarcinoma 9 | 2,716
non-small cell lung cancer 9 | 2,890
oligodendroglioma 9 | 2,850
pituitary cancer 9 | 1,972
primitive neuroectodermal tumor 9 | 3,035
Acquired scoliosis 8 | 281
Contracture 8 | 96
Contracture of joint 8 | 93
Curvature of spine 8 | 282
Epilepsy 8 | 792
Flexion contracture 8 | 93
Flexion contractures of joints 8 | 93
Gowers sign 8 | 24
Gowers sign present 8 | 24
MUSCULAR DYSTROPHY, CONGENITAL, 1C 8 | 9
Seizures 8 | 596
Cataract 7 | 297
Cerebellar Hypoplasia 7 | 61
Cleft Palate 7 | 271
Congenital muscular dystrophy (disorder) 7 | 14
Electromyogram abnormal 7 | 49
Infantile onset 7 | 238
Lens Opacities 7 | 231
Muscle eye brain disease 7 | 8
Muscle-eye-brain disease 7 | 8
Uranostaphyloschisis 7 | 167
dermatomyositis 7 | 966
pediatric high grade glioma 7 | 1,064
Cognitive delay 6 | 608
Gait abnormality 6 | 135
Global developmental delay 6 | 608
Highly variable severity 6 | 157
Impaired cognition 6 | 96
Liver cancer 6 | 604
Lordosis 6 | 54
Low Vision 6 | 174
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION), TYPE B, 1 6 | 7
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION), TYPE B, 14 6 | 7
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION), TYPE B, 2 6 | 7
Mental and motor retardation 6 | 608
Mental impairment 6 | 95
Motor delay 6 | 147
Muscle Hypertonia 6 | 88
Neuropathy 6 | 261
No development of motor milestones 6 | 147
Strabismus 6 | 270
Variable expressivity 6 | 157
Visual Impairment 6 | 174
adrenocortical carcinoma 6 | 1,428
astrocytic glioma 6 | 2,597
malignant mesothelioma 6 | 3,232
pancreatic cancer 6 | 2,398
Schizophrenia 5 | 1,160
interstitial cystitis 5 | 2,312
subependymal giant cell astrocytoma 5 | 2,287

Tissue

Endocrine System 50 | 18,159
Blood and immune system 49 | 16,909
Male tissues 49 | 17,142
Skin and soft tissues 49 | 17,230
Urinary Tract 49 | 16,678
Female tissues 48 | 17,400
Liver and Pancreas 48 | 16,750
Digestive Tract 47 | 17,369
Respiratory system 46 | 16,393
Nervous System 45 | 16,725
Cardiovascular System 42 | 15,192

Target Family

Non-IDG 35 | 12,091
Enzyme 13 | 4,145
Kinase 2 | 634
Ion Channel 1 | 344

Compartment GO Term

dystrophin-associated glycopro... 51 | 51
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nitric oxide synthase, brain NOS1 Tchem Enzyme -3.27741 1885.8 661
Muscle, skeletal receptor tyrosine-protein kinase MUSK Tchem Kinase -2.64791 454.9 373
Dystrophin DMD Tbio Non-IDG -3.50403 3129.8 363
Aquaporin-4 AQP4 Tbio Non-IDG -3.33435 2159.1 358
Dysbindin DTNBP1 Tbio Non-IDG -2.43980 286.6 321
Alpha-1-syntrophin SNTA1 Tbio Non-IDG -1.49227 31.4 254
Dystroglycan DAG1 Tbio Enzyme -2.77503 560.0 254
Basement membrane-specific heparan sulfate proteoglycan core protein HSPG2 Tbio Enzyme -2.99264 1021.1 225
Dysferlin DYSF Tbio Non-IDG -2.47585 338.6 210
Caveolin-3 CAV3 Tbio Non-IDG -2.58501 381.9 200