Development Level

Tbio 11 | 11,445
Tchem 6 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
decreased bone mineral content 1 | 151
decreased circulating insulin ... 1 | 76
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased basophil cell number 1 | 7
increased eosinophil cell numb... 1 | 11
increased large unstained cell... 1 | 5
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
small superior vagus ganglion 1 | 74

Disease

Cancer 16 | 2,499
ovarian cancer 13 | 8,520
lung cancer 11 | 4,740
Carcinoma 10 | 11,493
glioblastoma 10 | 5,792
osteosarcoma 9 | 7,950
psoriasis 9 | 6,694
Astrocytoma, Pilocytic 7 | 3,081
Hypersensitivity reaction type II disease 7 | 253
atypical teratoid / rhabdoid tumor 7 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung carcinoma 7 | 2,843
Multiple Sclerosis 6 | 540
cutaneous lupus erythematosus 6 | 1,057
ependymoma 6 | 4,679
pancreatic cancer 6 | 2,398
subependymal giant cell astrocytoma 6 | 2,287
ulcerative colitis 6 | 1,819
Arthritis 5 | 290
Autoimmune lymphoproliferative syndrome 5 | 11
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Diabetes Mellitus, Type 2 5 | 142
Liver disease 5 | 237
Rheumatoid arthritis 5 | 1,191
Schizophrenia 5 | 1,160
Splenomegaly 5 | 190
Vasculitis 5 | 80
adult high grade glioma 5 | 3,801
diabetes mellitus 5 | 1,728
pituitary cancer 5 | 1,972
Diabetes Mellitus, Experimental 4 | 108
Edema 4 | 81
Inflammatory bowel disease 4 | 151
Lung Neoplasms 4 | 232
Lung disease 4 | 142
Melanoma 4 | 711
Pancreatic Neoplasm 4 | 85
Pancreatic Neoplasms 4 | 85
Urticaria 4 | 67
colon cancer 4 | 1,478
gastric carcinoma 4 | 807
hepatocellular carcinoma 4 | 547
interstitial cystitis 4 | 2,312
juvenile dermatomyositis 4 | 1,187
malignant mesothelioma 4 | 3,232
medulloblastoma, large-cell 4 | 6,241
primary pancreatic ductal adenocarcinoma 4 | 1,109
tuberculosis 4 | 2,010
Adenocarcinoma 3 | 122
Anorexia 3 | 43
Anti-nuclear factor positive 3 | 18
Antiphospholipid antibody positivity 3 | 4
Atherosclerosis 3 | 291
Autoimmune hemolytic anemia 3 | 31
Autoimmune thrombocytopenia 3 | 22
Bipolar Disorder 3 | 666
Brain Injuries 3 | 65
Brain Ischemia 3 | 110
Breast Neoplasms 3 | 445
Breast cancer 3 | 3,578
Carcinoma, Hepatocellular 3 | 228
Cardiomyopathies 3 | 110
Colonic Neoplasms 3 | 142
Colorectal Neoplasms 3 | 243
Defective lymphocyte apoptosis 3 | 4
Drug Hypersensitivity 3 | 34
Drug allergy 3 | 36
Elevated serum IgA 3 | 5
Eosinophilia 3 | 28
Fever 3 | 138
Follicular hyperplasia 3 | 4
Hepatomegaly 3 | 285
Human immunodeficiency virus infectious disease 3 | 138
Idiopathic thrombocytopenia 3 | 22
Immune thrombocytopenic purpura 3 | 24
Increased IgM levels 3 | 16
Iron deficiency anemia 3 | 12
Kidney disease 3 | 430
Liver Failure, Acute 3 | 29
Liver carcinoma 3 | 240
Mammary Neoplasms 3 | 425
Neoplasm Metastasis 3 | 168
Platelet antibody positive 3 | 4
Pneumonia 3 | 174
Prostatic Neoplasms 3 | 495
Reduced delayed hypersensitivity 3 | 4
Reperfusion Injury 3 | 86
Rheumatoid factor positive (finding) 3 | 3
Status Epilepticus 3 | 98
Stomach Neoplasms 3 | 300
Toxic encephalopathy 3 | 141
Vascular disease 3 | 319
acute myeloid leukemia 3 | 783
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962

Tissue

Blood and immune system 18 | 16,909
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678
Cardiovascular System 17 | 15,192

Target Family

Non-IDG 14 | 12,091
Enzyme 3 | 4,145
Kinase 1 | 634

Compartment GO Term

death-inducing signaling compl... 18 | 18
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
FAS-associated factor 1 FAF1 Tbio Non-IDG -1.71858 56.5 209
Astrocytic phosphoprotein PEA-15 PEA15 Tbio Non-IDG -1.95527 108.9 355
Caspase-8 CASP8 Tchem Enzyme -3.54224 3121.4 1045
Receptor-interacting serine/threonine-protein kinase 1 RIPK1 Tchem Kinase -2.33991 211.8 375
Caspase-3 CASP3 Tchem Enzyme -4.32112 18132.3 1689
Protein AATF AATF Tbio Non-IDG -2.20561 160.5 230
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.32299 2090.2 2060
Tumor necrosis factor ligand superfamily member 10 TNFSF10 Tbio Non-IDG -2.87006 661.9 949
CASP8 and FADD-like apoptosis regulator CFLAR Tbio Non-IDG -2.89793 871.7 683
Tumor necrosis factor ligand superfamily member 6 FASLG Tbio Non-IDG -3.53551 3585.2 953