Development Level

Tbio 35 | 11,651
Tchem 13 | 1,388
Tclin 2 | 612
Tdark 1 | 6,593

Collection

Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal lens morphology 3 | 81
cataract 3 | 92
abnormal embryo size 2 | 220
abnormal epididymis morphology 2 | 42
abnormal heart morphology 2 | 162
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged epididymis 2 | 31
enlarged heart 2 | 210
female infertility 2 | 60
male infertility 2 | 123
preweaning lethality, incomple... 2 | 499
abnormal eye morphology 1 | 68
abnormal incisor morphology 1 | 4
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vertebral arch morpho... 1 | 9
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased grip strength 1 | 116
decreased kidney weight 1 | 1
decreased leukocyte cell numbe... 1 | 73
edema 1 | 59
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
fusion of vertebral arches 1 | 7
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating creatine... 1 | 5
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart rate 1 | 23
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased vertical activity 1 | 24
microphthalmia 1 | 26
shortened RR interval 1 | 17
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytopenia 1 | 56
urinary bladder obstruction 1 | 4
vertebral transformation 1 | 12

Disease

ovarian cancer 38 | 8,520
Carcinoma 32 | 11,493
Cancer 27 | 2,499
psoriasis 27 | 6,694
osteosarcoma 24 | 7,950
medulloblastoma, large-cell 23 | 6,241
glioblastoma 21 | 5,792
group 3 medulloblastoma 21 | 4,104
lung cancer 21 | 4,740
Breast cancer 17 | 3,578
malignant mesothelioma 17 | 3,232
ependymoma 16 | 4,679
adult high grade glioma 15 | 3,801
atypical teratoid / rhabdoid tumor 15 | 5,112
primitive neuroectodermal tumor 15 | 3,035
lung adenocarcinoma 14 | 2,716
oligodendroglioma 14 | 2,850
astrocytic glioma 12 | 2,597
pancreatic cancer 12 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
non-small cell lung cancer 11 | 2,890
astrocytoma 10 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
subependymal giant cell astrocytoma 10 | 2,287
Pick disease 9 | 1,894
colon cancer 9 | 1,478
invasive ductal carcinoma 9 | 2,951
nasopharyngeal carcinoma 9 | 1,058
ulcerative colitis 9 | 1,819
Kidney cancer 8 | 2,613
acute myeloid leukemia 8 | 783
acute quadriplegic myopathy 8 | 1,158
adrenocortical carcinoma 8 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
juvenile dermatomyositis 8 | 1,187
pituitary cancer 8 | 1,972
tuberculosis 8 | 2,010
Astrocytoma, Pilocytic 7 | 3,081
Intellectual disability 7 | 1,016
Rheumatoid arthritis 7 | 1,191
ductal carcinoma in situ 7 | 1,745
interstitial cystitis 7 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Atopic dermatitis 6 | 952
Multiple myeloma 6 | 1,332
Stomach Neoplasms 6 | 300
breast carcinoma 6 | 1,638
lung carcinoma 6 | 2,843
primary pancreatic ductal adenocarcinoma 6 | 1,109
progressive supranuclear palsy 6 | 676
Adenoma 5 | 167
Carcinoma, Hepatocellular 5 | 228
Colonic Neoplasms 5 | 142
Leukemia 5 | 104
Liver carcinoma 5 | 240
Prostatic Neoplasms 5 | 495
Schizophrenia 5 | 1,160
cystic fibrosis 5 | 1,696
diabetes mellitus 5 | 1,728
primary Sjogren syndrome 5 | 735
Breast Neoplasms 4 | 445
Dressler's syndrome 4 | 6
Endometriosis 4 | 540
Immune system cancer 4 | 140
Liver Cirrhosis, Experimental 4 | 769
Lung Neoplasms 4 | 232
Lymphoid leukemia 4 | 160
Mammary Neoplasms 4 | 425
Mammary Neoplasms, Experimental 4 | 154
Melanoma 4 | 711
Myocardial Infarction 4 | 151
Myopathy 4 | 185
Papilloma 4 | 44
Stomach cancer 4 | 30
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
dermatomyositis 4 | 966
interstitial lung disease 4 | 298
Acquired immunodeficiency syndrome 3 | 197
Adenocarcinoma 3 | 122
Anemia 3 | 365
Animal Mammary Neoplasms 3 | 136
Esophageal Squamous Cell Carcinoma 3 | 77
Hyperparathyroidism 3 | 48
Liver neoplasms 3 | 130
Mammary Neoplasms, Animal 3 | 136
Mental Depression 3 | 333
Mesothelioma, Malignant 3 | 105
Squamous cell carcinoma of esophagus 3 | 77
Vascular disease 3 | 319
Waldenstrons macroglobulinemia 3 | 765
chronic lymphosyte leukemia 3 | 204
cutaneous lupus erythematosus 3 | 1,057
familial melanoma 3 | 10
gastric carcinoma 3 | 807
hepatocellular carcinoma 3 | 547
medulloblastoma 3 | 720
pancreatic carcinoma 3 | 562
pediatric high grade glioma 3 | 1,064
sonic hedgehog group medulloblastoma 3 | 467
spina bifida 3 | 1,074

Tissue

Blood and immune system 50 | 16,909
Digestive Tract 50 | 17,369
Endocrine System 50 | 18,159
Female tissues 50 | 17,400
Liver and Pancreas 50 | 16,750
Male tissues 50 | 17,142
Nervous System 50 | 16,725
Skin and soft tissues 50 | 17,230
Urinary Tract 50 | 16,678
Cardiovascular System 49 | 15,192
Respiratory system 49 | 16,393

Target Family

Non-IDG 26 | 12,091
Kinase 14 | 634
Enzyme 7 | 4,145
Transcription Factor 3 | 1,400
Epigenetic 1 | 242

Compartment GO Term

cyclin-dependent protein kinas... 51 | 51
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cyclin-dependent kinase 6 CDK6 Tclin Kinase -2.71197 390.1 730
Protein HEXIM1 HEXIM1 Tbio Non-IDG -1.82459 64.7 348
Cyclin-L2 CCNL2 Tbio Non-IDG -2.03003 102.4 104
Cyclin-dependent kinase 3 CDK3 Tchem Kinase -1.44123 25.3 65
Cyclin-L1 CCNL1 Tbio Non-IDG -0.82661 6.96 183
AF4/FMR2 family member 4 AFF4 Tbio Transcription Factor -2.54994 350.8 174
Cyclin-dependent kinase inhibitor 2A CDKN2A Tbio Enzyme -3.72848 9058.6 1063
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.16448 1415.1 94
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.14393 1189.3 1251
Cyclin-dependent kinases regulatory subunit 1 CKS1B Tbio Enzyme -1.84127 63.8 192