Development Level

Tbio 9 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

decreased KLRG1+ CD4 alpha bet... 1 | 5
increased anti-nuclear antigen... 1 | 19
preweaning lethality, complete... 1 | 979

Disease

Photosensitive trichothiodystrophy 8 | 30
Carcinoma 7 | 11,493
Cockayne syndrome 7 | 60
Xeroderma pigmentosum group B 6 | 20
Xeroderma pigmentosum group D 5 | 33
ovarian cancer 5 | 8,520
Cancer 4 | 2,499
Xeroderma pigmentosum 4 | 43
lung cancer 4 | 4,740
Xeroderma pigmentosum group G 3 | 16
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
glioblastoma 3 | 5,792
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
Asthma 2 | 385
Astrocytoma, Pilocytic 2 | 3,081
Kidney cancer 2 | 2,613
Melanoma 2 | 711
Trichothiodystrophy 1, photosensitive 2 | 4
Trichothiodystrophy Syndromes 2 | 6
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
hepatocellular carcinoma 2 | 547
malignant mesothelioma 2 | 3,232
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
Abnormal nasal morphology 1 | 16
Achromatopsia 1 | 16
Alopecia areata 1 | 41
Animal Mammary Neoplasms 1 | 136
Arthralgia 1 | 90
Atrophic condition of skin 1 | 25
Basal cell carcinoma 1 | 54
Basal cell nevi 1 | 23
Brittle hair 1 | 25
Cachexia 1 | 50
Carcinoma, Squamous Cell 1 | 110
Cerebral calcification 1 | 43
Choreoathetoid movements 1 | 32
Choreoathetosis 1 | 32
Congenital Nonbullous Ichthyosiform Erythroderma 1 | 16
Conjunctival telangiectasis 1 | 14
Conjunctivitis 1 | 53
Conjunctivitis, recurrent 1 | 37
Death in childhood 1 | 14
Dental abnormalities 1 | 60
Dry skin 1 | 75
Ectropion 1 | 38
Enophthalmos 1 | 75
Entropion 1 | 22
Erythema 1 | 58
Everted lower lip vermilion 1 | 54
Exfoliative dermatitis 1 | 24
Fatigue 1 | 182
Flushing 1 | 60
Fractured hair 1 | 25
Fragile hair 1 | 25
Fragile nails 1 | 16
Freckles 1 | 33
Hyperkeratosis 1 | 50
Hyperkeratosis, Epidermolytic 1 | 7
Hyperpigmented macules 1 | 42
Hypoplasia of scrotum 1 | 24
IgG Deficiency 1 | 22
Joint stiffness 1 | 84
Kyphoscoliosis deformity of spine 1 | 60
Large beaked nose 1 | 5
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Mental deterioration 1 | 32
Muscular atrophy 1 | 71
Occupational Diseases 1 | 12
Papilloma 1 | 44
Peripheral demyelinating neuropathy 1 | 7
Photodysphoria 1 | 121
Photophobia 1 | 121
Photosensitivity of skin 1 | 51
Poikiloderma 1 | 14
Precociously senile appearance 1 | 18
Progressive mental retardation 1 | 37
Prominent metopic ridge 1 | 15
Protruding lower lip 1 | 54
Recurrent infections 1 | 48
Reduced tensile strength of hair 1 | 25
Rift Valley fever 1 | 14
Skin Abnormalities 1 | 37
Skin Neoplasms 1 | 69
Skin benign neoplasm 1 | 6
Spider Veins 1 | 17
Spinal muscular atrophy 1 | 34
Squamous cell carcinoma 1 | 129
Squamous cell carcinoma of skin 1 | 11
Sunken eyes 1 | 63
Telangiectasia of the skin 1 | 39
Telangiectasis 1 | 36
Tooth Abnormalities 1 | 69
Xeroderma pigmentosum group F 1 | 22
Xerosis 1 | 75
hypopigmented skin patch 1 | 59

Tissue

Blood and immune system 11 | 16,909
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Respiratory system 10 | 16,393

Target Family

Non-IDG 6 | 12,091
Enzyme 2 | 4,145
Kinase 2 | 634
Transporter 1 | 473

Compartment GO Term

cyclin-dependent protein kinas... 11 | 11
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium/calcium exchanger 2 SLC24A2 Tbio Transporter -1.39605 25.7 32
General transcription factor IIH subunit 2 GTF2H2 Tbio Non-IDG -1.32757 20.2 148
General transcription factor IIE subunit 1 GTF2E1 Tbio Non-IDG 0.16 0.68 153
TFIIH basal transcription factor complex helicase XPD subunit ERCC2 Tbio Enzyme -2.58326 365.8 191
Cyclin-dependent kinase 7 CDK7 Tchem Kinase -2.35186 219.0 582
Cyclin-H CCNH Tbio Non-IDG -2.02278 96.3 378
CDK-activating kinase assembly factor MAT1 MNAT1 Tbio Enzyme -2.13005 133.6 161
Cyclin-dependent kinase 2 CDK2 Tchem Kinase -3.44266 2522.8 1114
General transcription factor IIH subunit 1 GTF2H1 Tbio Non-IDG -1.65323 46.0 231
General transcription factor IIH subunit 5 GTF2H5 Tbio Non-IDG -1.62301 48.3 44