Development Level

Tbio 81 | 11,445
Tchem 12 | 1,598
Tclin 9 | 613
Tdark 5 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 6 | 979
hyperactivity 4 | 148
preweaning lethality, incomple... 4 | 499
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
increased circulating sodium l... 3 | 71
increased total body fat amoun... 3 | 134
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
abnormal sleep behavior 2 | 70
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hydrometra 2 | 53
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased circulating free fat... 2 | 20
increased circulating potassiu... 2 | 29
increased erythrocyte cell num... 2 | 39
small superior vagus ganglion 2 | 74
abnormal cecum morphology 1 | 7
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal heart shape 1 | 5
abnormal nail morphology 1 | 8
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal tooth morphology 1 | 24
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating glucose ... 1 | 126
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating unsatura... 1 | 2
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased heart rate variabili... 1 | 13
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
enlarged cecum 1 | 5
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
enlarged seminal vesicle 1 | 10
hydrops fetalis 1 | 1
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating insulin ... 1 | 3
increased circulating iron lev... 1 | 30
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
increased vertical activity 1 | 24
microphthalmia 1 | 26
mydriasis 1 | 6
thin ventricular wall 1 | 24
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 69 | 11,493
psoriasis 58 | 6,694
ovarian cancer 55 | 8,520
osteosarcoma 44 | 7,950
medulloblastoma, large-cell 43 | 6,241
glioblastoma 42 | 5,792
ependymoma 35 | 4,679
atypical teratoid / rhabdoid tumor 34 | 5,112
lung carcinoma 33 | 2,843
Astrocytoma, Pilocytic 32 | 3,081
lung cancer 32 | 4,740
malignant mesothelioma 30 | 3,232
adult high grade glioma 28 | 3,801
invasive ductal carcinoma 27 | 2,951
diabetes mellitus 25 | 1,728
astrocytic glioma 24 | 2,597
subependymal giant cell astrocytoma 24 | 2,287
group 3 medulloblastoma 23 | 4,104
non-small cell lung cancer 23 | 2,890
Breast cancer 22 | 3,578
oligodendroglioma 22 | 2,850
Cancer 21 | 2,499
Pick disease 21 | 1,894
interstitial cystitis 21 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
Rheumatoid arthritis 20 | 1,191
Autosomal recessive predisposition 19 | 1,442
Kidney cancer 18 | 2,613
lung adenocarcinoma 18 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
pancreatic cancer 17 | 2,398
primitive neuroectodermal tumor 17 | 3,035
tuberculosis 17 | 2,010
cutaneous lupus erythematosus 16 | 1,057
ductal carcinoma in situ 16 | 1,745
pituitary cancer 16 | 1,972
Schizophrenia 15 | 1,160
esophageal adenocarcinoma 15 | 737
Bipolar Disorder 14 | 666
breast carcinoma 14 | 1,638
cystic fibrosis 14 | 1,696
Alzheimer's disease 13 | 658
Multiple Sclerosis 13 | 540
adrenocortical carcinoma 13 | 1,428
Multiple myeloma 12 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
Alcoholic Intoxication, Chronic 11 | 289
Cataract 8 multiple types 11 | 33
Down syndrome 11 | 499
Epilepsy 10 | 792
Kidney disease 10 | 430
Liver cancer 10 | 604
gastric carcinoma 10 | 807
juvenile dermatomyositis 10 | 1,187
Hypersensitivity reaction type II disease 9 | 253
Parkinson's disease 9 | 392
acute quadriplegic myopathy 9 | 1,158
astrocytoma 9 | 1,146
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
pediatric high grade glioma 9 | 1,064
Atopic dermatitis 8 | 952
Diarrhea 8 | 253
Duchenne muscular dystrophy 8 | 601
Hepatitis B 8 | 108
Liver Cirrhosis, Experimental 8 | 769
Major Depressive Disorder 8 | 301
Obesity 8 | 678
group 4 medulloblastoma 8 | 1,855
primary pancreatic ductal adenocarcinoma 8 | 1,109
sarcoidosis 8 | 370
ulcerative colitis 8 | 1,819
Gaucher disease type 1 7 | 180
Liver disease 7 | 237
Melanoma 7 | 711
Neurodegenerative disease 7 | 414
Prostatic Neoplasms 7 | 495
Vascular disease 7 | 319
active Crohn's disease 7 | 922
spina bifida 7 | 1,074
Atherosclerosis 6 | 291
Cognitive delay 6 | 608
Depressive disorder 6 | 409
Dull intelligence 6 | 645
Global developmental delay 6 | 608
Heart disease 6 | 306
Hypertension 6 | 396
Hypertensive disease 6 | 292
Intellectual disability 6 | 1,016
Low intelligence 6 | 645
Lung Neoplasms 6 | 232
Mental Retardation 6 | 645
Mental and motor retardation 6 | 608
Mental deficiency 6 | 645
Poor school performance 6 | 645
Unipolar Depression 6 | 250
Waldenstrons macroglobulinemia 6 | 765
acute myeloid leukemia 6 | 783
dermatomyositis 6 | 966
nephrosclerosis 6 | 333
progressive supranuclear palsy 6 | 676

Tissue

Skin and soft tissues 104 | 17,230
Digestive Tract 102 | 17,369
Endocrine System 101 | 18,159
Female tissues 101 | 17,400
Blood and immune system 99 | 16,909
Liver and Pancreas 99 | 16,750
Male tissues 98 | 17,142
Urinary Tract 98 | 16,678
Respiratory system 97 | 16,393
Nervous System 96 | 16,725
Cardiovascular System 90 | 15,192

Target Family

Non-IDG 78 | 12,091
Enzyme 8 | 4,145
Transporter 8 | 473
GPCR 7 | 408
Kinase 3 | 634
Transcription Factor 2 | 1,400
Ion Channel 1 | 344

Compartment GO Term

clathrin-coated vesicle membra... 107 | 107
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor-like 5 protein TCFL5 Tbio Transcription Factor -2.62447 404.7 161
Solute carrier family 2, facilitated glucose transporter member 8 SLC2A8 Tbio Transporter -1.54482 35.6 110
C-type lectin domain family 4 member K CD207 Tbio Non-IDG -2.49714 321.5 295
5,6-dihydroxyindole-2-carboxylic acid oxidase TYRP1 Tbio Enzyme -2.95336 876.7 309
Synaptotagmin-2 SYT2 Tbio Non-IDG -1.93503 86.7 222
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.52158 32564.4 32
Synergin gamma SYNRG Tdark Non-IDG -1.69335 48.2 24
Serotransferrin TF Tbio Non-IDG -4.15070 13447.9 1168
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.43851 2558.3 1677
Clathrin heavy chain 1 CLTC Tbio Non-IDG -1.66258 38.8 231