Development Level

Tbio 35 | 11,445
Tchem 6 | 1,598
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased vertical activity 3 | 208
preweaning lethality, complete... 3 | 979
abnormal heart morphology 2 | 162
decreased circulating serum al... 2 | 82
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hydrometra 2 | 53
hyperactivity 2 | 148
increased circulating choleste... 2 | 66
increased circulating free fat... 2 | 20
small superior vagus ganglion 2 | 74
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal heart shape 1 | 5
abnormal nail morphology 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal tooth morphology 1 | 24
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating glucose ... 1 | 126
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating unsatura... 1 | 2
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased heart rate variabili... 1 | 13
enlarged cecum 1 | 5
enlarged seminal vesicle 1 | 10
hydrops fetalis 1 | 1
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating insulin ... 1 | 3
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26

Disease

Carcinoma 25 | 11,493
psoriasis 25 | 6,694
ovarian cancer 21 | 8,520
diabetes mellitus 14 | 1,728
ependymoma 14 | 4,679
lung carcinoma 14 | 2,843
glioblastoma 13 | 5,792
interstitial cystitis 12 | 2,312
Astrocytoma, Pilocytic 11 | 3,081
atypical teratoid / rhabdoid tumor 11 | 5,112
invasive ductal carcinoma 11 | 2,951
medulloblastoma, large-cell 11 | 6,241
non-small cell lung cancer 11 | 2,890
osteosarcoma 11 | 7,950
Rheumatoid arthritis 10 | 1,191
lung cancer 10 | 4,740
Breast cancer 9 | 3,578
Multiple Sclerosis 9 | 540
astrocytic glioma 9 | 2,597
subependymal giant cell astrocytoma 9 | 2,287
Cancer 8 | 2,499
adult high grade glioma 8 | 3,801
breast carcinoma 8 | 1,638
ductal carcinoma in situ 8 | 1,745
esophageal adenocarcinoma 8 | 737
group 3 medulloblastoma 8 | 4,104
malignant mesothelioma 8 | 3,232
oligodendroglioma 8 | 2,850
tuberculosis 8 | 2,010
cystic fibrosis 7 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
primitive neuroectodermal tumor 7 | 3,035
Autosomal recessive predisposition 6 | 1,442
Cataract 8 multiple types 6 | 33
Hepatitis B 6 | 108
Hypersensitivity reaction type II disease 6 | 253
lung adenocarcinoma 6 | 2,716
Alzheimer's disease 5 | 658
Berylliosis 5 | 28
Down syndrome 5 | 499
Duchenne muscular dystrophy 5 | 601
Kidney cancer 5 | 2,613
Liver disease 5 | 237
Pick disease 5 | 1,894
Type 1 diabetes mellitus 5 | 109
active Crohn's disease 5 | 922
adrenocortical carcinoma 5 | 1,428
head and neck cancer and chronic obstructive pulmonary disease 5 | 239
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
juvenile dermatomyositis 5 | 1,187
pancreatic cancer 5 | 2,398
sarcoidosis 5 | 370
ulcerative colitis 5 | 1,819
Becker muscular dystrophy 4 | 191
Juvenile rheumatoid arthritis 4 | 111
Lung Neoplasms 4 | 232
Narcolepsy 4 | 72
Vasculitis 4 | 80
cutaneous lupus erythematosus 4 | 1,057
gastric carcinoma 4 | 807
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
Adenocarcinoma 3 | 122
Alcoholic Intoxication, Chronic 3 | 289
Arcus Senilis 3 | 11
Arcus juvenilis 3 | 5
Atherosclerosis 3 | 291
Atopic dermatitis 3 | 952
Cardiovascular system disease 3 | 246
Coronary Disease 3 | 25
Coronary artery disease 3 | 268
Coronary heart disease 3 | 16
Diphtheria 3 | 40
Frontal bossing 3 | 157
Hypercholesterolemia 3 | 44
Hyperlipidemia 3 | 43
Hypotrophic malar bone 3 | 129
Lipid metabolism disorder 3 | 114
Liver Cirrhosis 3 | 181
Liver cancer 3 | 604
Long philtrum 3 | 137
Malar flattening 3 | 129
Melanoma 3 | 711
Mucoepidermoid carcinoma 3 | 26
Myocardial Infarction 3 | 151
Myositis 3 | 30
Parkinson's disease 3 | 392
Systemic lupus erythematosus 3 | 194
Vascular disease 3 | 319
active ulcerative colitis 3 | 764
chronic rhinosinusitis 3 | 512
dermatomyositis 3 | 966
fibroadenoma 3 | 559
interstitial lung disease 3 | 298
limb girdle muscular dystrophy 2A 3 | 213
nephrosclerosis 3 | 333
non-small cell lung carcinoma 3 | 317
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Skin and soft tissues 40 | 17,230
Digestive Tract 39 | 17,369
Female tissues 39 | 17,400
Blood and immune system 38 | 16,909
Liver and Pancreas 37 | 16,750
Endocrine System 36 | 18,159
Male tissues 36 | 17,142
Respiratory system 36 | 16,393
Urinary Tract 36 | 16,678
Cardiovascular System 35 | 15,192
Nervous System 35 | 16,725

Target Family

Non-IDG 32 | 12,091
Enzyme 4 | 4,145
GPCR 3 | 408
Kinase 2 | 634
Transporter 1 | 473

Compartment GO Term

clathrin-coated endocytic vesi... 42 | 42
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5,6-dihydroxyindole-2-carboxylic acid oxidase TYRP1 Tbio Enzyme -2.95336 876.7 309
C-type lectin domain family 4 member K CD207 Tbio Non-IDG -2.49714 321.5 295
Clathrin heavy chain 1 CLTC Tbio Non-IDG -1.66258 38.8 231
Keratin, type I cuticular Ha7 KRT37 Tdark Non-IDG -1.63304 35.5 15
Putative tyrosine-protein phosphatase auxilin DNAJC6 Tbio Enzyme -1.74103 58.7 98
Calcium/calmodulin-dependent protein kinase type 1B PNCK Tbio Kinase -2.14753 82.1 161
HLA class II histocompatibility antigen, DQ alpha 2 chain HLA-DQA2 Tbio Non-IDG -2.26047 184.2 169
Unconventional myosin-Ig MYO1G Tbio Non-IDG -1.98465 98.3 35
UDP-glucuronosyltransferase 2B17 UGT2B17 Tbio Enzyme -1.91917 91.6 20
High affinity immunoglobulin gamma Fc receptor IB FCGR1B Tbio Non-IDG -0.35592 2.04 66