Development Level

Tbio 30 | 11,651
Tdark 3 | 6,593

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal bone structure 2 | 187
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal coat- hair morphology 1 | 19
abnormal embryo size 1 | 220
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged seminal vesicle 1 | 10
hydroencephaly 1 | 14
hyperactivity 1 | 148
hypoactivity 1 | 132
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating fructosa... 1 | 13
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
short tibia 1 | 97
small testis 1 | 58

Disease

ovarian cancer 23 | 8,520
Carcinoma 20 | 11,493
osteosarcoma 16 | 7,950
medulloblastoma, large-cell 12 | 6,241
glioblastoma 11 | 5,792
lung cancer 11 | 4,740
atypical teratoid / rhabdoid tumor 10 | 5,112
psoriasis 10 | 6,694
adult high grade glioma 8 | 3,801
ependymoma 8 | 4,679
Autosomal recessive predisposition 7 | 1,442
Kidney cancer 7 | 2,613
Pick disease 7 | 1,894
malignant mesothelioma 7 | 3,232
Astrocytoma, Pilocytic 6 | 3,081
Breast cancer 6 | 3,578
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
group 3 medulloblastoma 5 | 4,104
lung adenocarcinoma 5 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Amyotrophic lateral sclerosis 4 | 451
Multiple myeloma 4 | 1,332
astrocytic glioma 4 | 2,597
dermatomyositis 4 | 966
group 4 medulloblastoma 4 | 1,855
hereditary spastic paraplegia 4 | 318
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
pediatric high grade glioma 4 | 1,064
primary pancreatic ductal adenocarcinoma 4 | 1,109
subependymal giant cell astrocytoma 4 | 2,287
Intellectual disability 3 | 1,016
Muscle hypotonia 3 | 571
Neurodegenerative disease 3 | 414
Progressive disorder 3 | 142
Short stature 3 | 531
Waldenstrons macroglobulinemia 3 | 765
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
pancreatic cancer 3 | 2,398
tuberculosis and treatment for 6 months 3 | 409
ulcerative colitis 3 | 1,819
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Acquired scoliosis 2 | 281
Bipolar Disorder 2 | 666
Brachycephaly 2 | 88
Cognitive delay 2 | 608
Concave bridge of nose 2 | 195
Congenital small ears 2 | 48
Curvature of spine 2 | 282
Decreased tendon reflex 2 | 122
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Dull intelligence 2 | 645
Epilepsy 2 | 792
Frontal bossing 2 | 157
Global developmental delay 2 | 608
Globe of eye large 2 | 20
Hydrophthalmos 2 | 19
Hypoplasia of corpus callosum 2 | 90
Infantile onset 2 | 238
Low Vision 2 | 174
Low intelligence 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Neurogenic Muscular Atrophy 2 | 139
Poor school performance 2 | 645
Reflex, Deep Tendon, Absent 2 | 92
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Severe mental retardation (I.Q. 20-34) 2 | 99
Short neck 2 | 140
Small head 2 | 374
Strabismus 2 | 270
Uranostaphyloschisis 2 | 167
Visual Impairment 2 | 174
acute myeloid leukemia 2 | 783
aldosterone-producing adenoma 2 | 665
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
gastric cancer 2 | 459
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
mucosa-associated lymphoid tissue lymphoma 2 | 484
muscle degeneration 2 | 139
non-small cell lung cancer 2 | 2,890
periodontitis 2 | 293
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 416
spina bifida 2 | 1,074
tuberculosis 2 | 2,010

Tissue

Blood and immune system 33 | 16,909
Cardiovascular System 33 | 15,192
Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Liver and Pancreas 33 | 16,750
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Respiratory system 33 | 16,393
Skin and soft tissues 33 | 17,230
Urinary Tract 33 | 16,678

Target Family

Non-IDG 21 | 12,091
Enzyme 8 | 4,145
Transporter 3 | 473
Kinase 1 | 634

Compartment GO Term

cis-Golgi network 33 | 33
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
A-kinase anchor protein 9 AKAP9 Tbio Enzyme -2.22554 169.7 142
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 B3GAT3 Tbio Enzyme -1.43805 32.2 112
Protein Hook homolog 3 HOOK3 Tbio Non-IDG -1.22079 6.06 60
Phospholipase DDHD2 DDHD2 Tbio Enzyme -1.23833 16.6 49
Golgin subfamily A member 2 GOLGA2 Tbio Non-IDG -1.95809 83.3 241
Metallophosphoesterase 1 MPPE1 Tbio Enzyme -0.58358 3.78 111
Transmembrane emp24 domain-containing protein 10 TMED10 Tbio Non-IDG -1.46644 31.9 300
Intraflagellar transport protein 20 homolog IFT20 Tbio Non-IDG -1.18376 15.2 90
Antizyme inhibitor 2 AZIN2 Tbio Enzyme -2.05244 97.6 50
GDP-fucose transporter 1 SLC35C1 Tbio Transporter -1.06011 11.8 43