Development Level

Tbio 31 | 10,625
Tdark 4 | 7,003

Collection

Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 633
decreased lumbar vertebrae num... 2 | 62
decreased total body fat amoun... 2 | 186
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal head morphology 1 | 10
abnormal lung morphology 1 | 15
abnormal testis morphology 1 | 30
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased erythrocyte cell num... 1 | 43
decreased lactate dehydrogenas... 1 | 14
decreased lean body mass 1 | 195
embryonic lethality prior to t... 1 | 187
hyperactivity 1 | 108
hypoactivity 1 | 89
increased circulating alkaline... 1 | 119
increased circulating chloride... 1 | 43
increased circulating fructosa... 1 | 11
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased sacral vertebrae num... 1 | 62
short tibia 1 | 82
small testis 1 | 37

Disease

ovarian cancer 24 | 8,491
osteosarcoma 16 | 7,933
medulloblastoma, large-cell 13 | 6,234
glioblastoma 12 | 5,572
atypical teratoid / rhabdoid tumor 10 | 4,369
psoriasis 10 | 6,685
lung cancer 9 | 4,473
adult high grade glioma 8 | 2,148
malignant mesothelioma 8 | 3,163
Pick disease 7 | 1,893
pilocytic astrocytoma 7 | 3,086
primitive neuroectodermal tumor 7 | 3,031
oligodendroglioma 6 | 2,849
Breast cancer 5 | 3,098
astrocytic glioma 5 | 2,241
ependymoma 5 | 2,514
lung adenocarcinoma 5 | 2,714
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
pediatric high grade glioma 5 | 2,712
subependymal giant cell astrocytoma 5 | 2,287
Carcinoma 4 | 2,147
Multiple myeloma 4 | 1,327
astrocytoma 4 | 1,493
dermatomyositis 4 | 966
group 4 medulloblastoma 4 | 1,875
hereditary spastic paraplegia 4 | 313
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
invasive ductal carcinoma 4 | 2,950
posterior fossa group A ependymoma 4 | 1,511
primary pancreatic ductal adenocarcinoma 4 | 1,271
tuberculosis and treatment for 6 months 4 | 686
ulcerative colitis 4 | 2,087
Amyotrophic Lateral Sclerosis 3 | 432
Intellectual disability 3 | 573
Neurodegenerative disease 3 | 383
Waldenstrons macroglobulinemia 3 | 764
acute quadriplegic myopathy 3 | 1,157
colon cancer 3 | 1,475
cutaneous lupus erythematosus 3 | 1,056
medulloblastoma 3 | 1,524
pancreatic cancer 3 | 2,300
posterior fossa group B ependymoma 3 | 1,530
IGA Glomerulonephritis 2 | 454
Peripheral Neuropathy 2 | 303
Rheumatoid Arthritis 2 | 1,170
active ulcerative colitis 2 | 477
acute myeloid leukemia 2 | 785
aldosterone-producing adenoma 2 | 664
atypical teratoid/rhabdoid tumor 2 | 1,095
diabetes mellitus 2 | 1,663
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
gastric cancer 2 | 436
group 3 medulloblastoma 2 | 2,254
hepatocellular carcinoma 2 | 550
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
juvenile dermatomyositis 2 | 1,189
lung carcinoma 2 | 2,844
mucosa-associated lymphoid tissue lymphoma 2 | 480
non primary Sjogren syndrome sicca 2 | 840
non-small cell lung cancer 2 | 2,798
pituitary cancer 2 | 1,972
spina bifida 2 | 1,064
Arrhythmogenic right ventricular cardiomyopathy 1 | 27
Arsenic Poisoning 1 | 59
Autosomal dominant cerebellar ataxia 1 | 34
Bipolar Disorder 1 | 266
Cardiomyopathy 1 | 110
Chromosome 17q11.2 deletion syndrome, 1.4Mb 1 | 14
Common variable immunodeficiency 1 | 98
Congenital disorder of glycosylation 1 | 53
Craniofacial Abnormalities 1 | 147
Dermatologic disorders 1 | 65
Gaucher disease type 3 1 | 76
Hydrocephalus 1 | 60
Infectious mononucleosis 1 | 15
Long QT syndrome 1 | 53
Long QT syndrome 1 1 | 12
Long QT syndrome 11 1 | 1
Lymphoma 1 | 57
Mucopolysaccharidosis III 1 | 6
Muscle-eye-brain disease 1 | 8
Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain and Eye Anomalies), Type A, 1 1 | 6
Muscular dystrophy 1 | 48
Periventricular nodular heterotopia 1 | 26
Prostate carcinoma 1 | 1
Radioulnar synostosis 1 | 13
Renal Cell Carcinoma 1 | 199
Retinitis pigmentosa 1 | 156
Romano-Ward Syndrome 1 | 12
Sengers syndrome 1 | 17
Sjogren's syndrome 1 | 23
Testicular cancer 1 | 24
cystic fibrosis and chronic rhinosinusitis 1 | 213
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
limb-girdle muscular dystrophy 1 | 36
ovarian neoplasm 1 | 97
sarcoidosis 1 | 368
thrombocytopenia-absent radius syndrome 1 | 15

Tissue

Blood and immune system 35 | 17,994
Cardiovascular System 35 | 17,957
Digestive Tract 35 | 18,472
Endocrine System 35 | 18,511
Female tissues 35 | 18,646
Liver and Pancreas 35 | 18,135
Male tissues 35 | 17,968
Nervous System 35 | 18,560
Respiratory system 35 | 17,483
Skin and soft tissues 35 | 18,114
Urinary Tract 35 | 18,443

Target Family

Non-IDG 23 | 11,969
Enzyme 8 | 4,146
Transporter 3 | 473
Kinase 1 | 634

Compartment GO Term

cis-Golgi network 35 | 35
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein angel homolog 1 ANGEL1 Tbio Non-IDG -0.17609 0.98 83
Phospholipase DDHD2 DDHD2 Tbio Enzyme -1.21059 15.3 39
Bcl-2-related ovarian killer protein BOK Tbio Non-IDG -1.58634 37.9 184
Thyroid receptor-interacting protein 11 TRIP11 Tbio Non-IDG -1.37484 25.8 66
Ras-related protein Rab-30 RAB30 Tbio Enzyme -0.74252 5.83 78
Solute carrier family 35 member C2 SLC35C2 Tdark Transporter -0.41775 2.77 25
N-terminal kinase-like protein SCYL1 Tbio Kinase -1.67381 51.7 128
Antizyme inhibitor 2 AZIN2 Tbio Enzyme -2.02657 94.5 45
Fukutin FKTN Tbio Non-IDG -2.34002 228.4 116
Transmembrane emp24 domain-containing protein 10 TMED10 Tbio Non-IDG -1.45219 31.4 277