Development Level

Tbio 62 | 11,178
Tchem 13 | 1,885
Tdark 7 | 6,569

IMPC Phenotype

preweaning lethality, complete... 8 | 979
increased startle reflex 3 | 112
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased vertical activity 2 | 208
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal ovary morphology 1 | 7
abnormal placement of pupils 1 | 6
abnormal thymus morphology 1 | 7
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased eosinophil cell numb... 1 | 24
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged thymus 1 | 5
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
polycystic kidney 1 | 15
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small testis 1 | 58
tremors 1 | 39

Disease

Carcinoma 59 | 11,192
ovarian cancer 52 | 8,297
osteosarcoma 42 | 7,766
Cancer 35 | 2,388
lung cancer 35 | 4,607
medulloblastoma, large-cell 35 | 6,086
psoriasis 26 | 6,514
atypical teratoid / rhabdoid tumor 25 | 4,971
Breast cancer 24 | 3,469
glioblastoma 23 | 5,635
group 3 medulloblastoma 23 | 4,002
Kidney cancer 18 | 2,548
Intellectual disability 17 | 998
Short stature 17 | 514
malignant mesothelioma 17 | 3,135
Dull intelligence 15 | 634
Low intelligence 15 | 634
Mental Retardation 15 | 634
Mental deficiency 15 | 634
Poor school performance 15 | 634
Small head 15 | 366
pancreatic cancer 15 | 2,322
Autosomal recessive predisposition 14 | 1,407
Cognitive delay 14 | 596
Global developmental delay 14 | 596
Mental and motor retardation 14 | 596
primitive neuroectodermal tumor 14 | 2,957
Fanconi anemia 13 | 56
Melanoma 12 | 689
Thrombocytopenia 12 | 193
adult high grade glioma 12 | 3,701
astrocytic glioma 12 | 2,530
diabetes mellitus 12 | 1,683
ependymoma 12 | 4,559
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,204
non primary Sjogren syndrome sicca 12 | 861
Decreased platelet count 11 | 110
Nijmegen breakage syndrome 11 | 23
Pick disease 11 | 1,856
oligodendroglioma 11 | 2,768
Anemia 10 | 353
Ataxia telangiectasia 10 | 33
Breast Neoplasms 10 | 423
Dyskeratosis congenita 10 | 24
Mammary Neoplasms 10 | 403
Multiple myeloma 10 | 1,296
Xeroderma pigmentosum 10 | 42
lung adenocarcinoma 10 | 2,627
Fetal Growth Retardation 9 | 186
Glioma 9 | 73
Infant, Small for Gestational Age 9 | 174
Intrauterine retardation 9 | 174
Liver cancer 9 | 589
Lung Neoplasms 9 | 217
Prostatic Neoplasms 9 | 472
Telangiectasia of the skin 9 | 38
hypopigmented skin patch 9 | 59
Bone marrow hypocellularity 8 | 20
Hereditary Breast and Ovarian Cancer Syndrome 8 | 13
Osteoporosis 8 | 348
Pancreatic Neoplasm 8 | 82
Sparse scalp hair 8 | 41
Tracheoesophageal Fistula 8 | 33
Waldenstrons macroglobulinemia 8 | 742
acute quadriplegic myopathy 8 | 1,133
breast carcinoma 8 | 1,589
hepatocellular carcinoma 8 | 536
non-small cell lung cancer 8 | 2,799
ulcerative colitis 8 | 1,765
Aplasia/Hypoplasia of the skin 7 | 16
Cellular immunodeficiency 7 | 17
Chromosome Breakage 7 | 35
DOID:2627 7 | 89
Dental caries 7 | 157
Dry skin 7 | 74
Hyperhidrosis disorder 7 | 78
Hyperpigmented macules 7 | 41
Increased sweating 7 | 78
Leukopenia 7 | 72
Lymphoid leukemia 7 | 156
Pancreatic Neoplasms 7 | 82
Recurrent respiratory infections 7 | 138
Seizures 7 | 584
Skin Ulcer 7 | 48
Stomach Neoplasms 7 | 287
Sweating 7 | 78
Werner syndrome 7 | 29
Xerosis 7 | 74
colon cancer 7 | 1,428
juvenile dermatomyositis 7 | 1,147
non-small cell lung carcinoma 7 | 302
periodontitis 7 | 280
subependymal giant cell astrocytoma 7 | 2,230
Epilepsy 6 | 775
Failure to gain weight 6 | 359
Hemoglobin low 6 | 123
Pediatric failure to thrive 6 | 359
Prostate cancer 6 | 164
progressive supranuclear palsy 6 | 656
tuberculosis 6 | 1,963

Tissue

Endocrine System 81 | 18,159
Blood and immune system 80 | 16,909
Digestive Tract 80 | 17,369
Female tissues 80 | 17,400
Liver and Pancreas 80 | 16,750
Male tissues 80 | 17,142
Respiratory system 79 | 16,393
Skin and soft tissues 79 | 17,230
Urinary Tract 79 | 16,678
Nervous System 77 | 16,725
Cardiovascular System 76 | 15,192

Target Family

Non-IDG 47 | 12,091
Enzyme 21 | 4,145
Transcription Factor 8 | 1,400
Epigenetic 3 | 242
Kinase 2 | 634
GPCR 1 | 408

Compartment GO Term

chromosome, telomeric region 82 | 82
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA cross-link repair 1A protein DCLRE1A Tbio Non-IDG -1.94675 90.4 92
Non-structural maintenance of chromosomes element 3 homolog NSMCE3 Tbio Non-IDG -1.07832 11.9 26
E3 SUMO-protein ligase NSE2 NSMCE2 Tbio Enzyme -1.37520 25.7 196
Telomeric repeat-binding factor 2 TERF2 Tbio Transcription Factor -2.23836 174.6 367
Tuftelin-interacting protein 11 TFIP11 Tbio Non-IDG -1.75990 66.6 84
H/ACA ribonucleoprotein complex subunit 3 NOP10 Tbio Non-IDG -1.36742 17.7 34
Telomere length regulation protein TEL2 homolog TELO2 Tbio Non-IDG -0.93554 9.48 94
Leucine-rich repeat and WD repeat-containing protein 1 LRWD1 Tbio Non-IDG -1.08139 12.9 65
Cleft lip and palate transmembrane protein 1-like protein CLPTM1L Tbio Non-IDG -1.73603 53.2 158
Telomerase-binding protein EST1A SMG6 Tbio Enzyme -1.48788 32.6 37