Development Level

Tbio 62 | 11,445
Tchem 13 | 1,598
Tdark 7 | 6,588

IMPC Phenotype

preweaning lethality, complete... 8 | 979
increased startle reflex 3 | 112
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased vertical activity 2 | 208
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal ovary morphology 1 | 7
abnormal placement of pupils 1 | 6
abnormal thymus morphology 1 | 7
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased eosinophil cell numb... 1 | 24
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged thymus 1 | 5
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
polycystic kidney 1 | 15
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small testis 1 | 58
tremors 1 | 39

Disease

Carcinoma 59 | 11,493
ovarian cancer 52 | 8,520
osteosarcoma 42 | 7,950
Cancer 35 | 2,499
lung cancer 35 | 4,740
medulloblastoma, large-cell 35 | 6,241
psoriasis 26 | 6,694
atypical teratoid / rhabdoid tumor 25 | 5,112
Breast cancer 24 | 3,578
glioblastoma 23 | 5,792
group 3 medulloblastoma 23 | 4,104
Kidney cancer 18 | 2,613
Intellectual disability 17 | 1,016
Short stature 17 | 531
malignant mesothelioma 17 | 3,232
Dull intelligence 15 | 645
Low intelligence 15 | 645
Mental Retardation 15 | 645
Mental deficiency 15 | 645
Poor school performance 15 | 645
Small head 15 | 374
pancreatic cancer 15 | 2,398
Autosomal recessive predisposition 14 | 1,442
Cognitive delay 14 | 608
Global developmental delay 14 | 608
Mental and motor retardation 14 | 608
primitive neuroectodermal tumor 14 | 3,035
Fanconi anemia 13 | 56
Melanoma 12 | 711
Thrombocytopenia 12 | 197
adult high grade glioma 12 | 3,801
astrocytic glioma 12 | 2,597
diabetes mellitus 12 | 1,728
ependymoma 12 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
non primary Sjogren syndrome sicca 12 | 891
Decreased platelet count 11 | 111
Nijmegen breakage syndrome 11 | 24
Pick disease 11 | 1,894
oligodendroglioma 11 | 2,850
Anemia 10 | 365
Ataxia telangiectasia 10 | 34
Breast Neoplasms 10 | 445
Dyskeratosis congenita 10 | 24
Mammary Neoplasms 10 | 425
Multiple myeloma 10 | 1,332
Xeroderma pigmentosum 10 | 43
lung adenocarcinoma 10 | 2,716
Fetal Growth Retardation 9 | 189
Glioma 9 | 74
Infant, Small for Gestational Age 9 | 176
Intrauterine retardation 9 | 176
Liver cancer 9 | 604
Lung Neoplasms 9 | 232
Prostatic Neoplasms 9 | 495
Telangiectasia of the skin 9 | 39
hypopigmented skin patch 9 | 59
Bone marrow hypocellularity 8 | 20
Hereditary Breast and Ovarian Cancer Syndrome 8 | 14
Osteoporosis 8 | 363
Pancreatic Neoplasm 8 | 85
Sparse scalp hair 8 | 42
Tracheoesophageal Fistula 8 | 36
Waldenstrons macroglobulinemia 8 | 765
acute quadriplegic myopathy 8 | 1,158
breast carcinoma 8 | 1,638
hepatocellular carcinoma 8 | 547
non-small cell lung cancer 8 | 2,890
ulcerative colitis 8 | 1,819
Aplasia/Hypoplasia of the skin 7 | 16
Cellular immunodeficiency 7 | 17
Chromosome Breakage 7 | 36
DOID:2627 7 | 94
Dental caries 7 | 164
Dry skin 7 | 75
Hyperhidrosis disorder 7 | 81
Hyperpigmented macules 7 | 42
Increased sweating 7 | 81
Leukopenia 7 | 72
Lymphoid leukemia 7 | 160
Pancreatic Neoplasms 7 | 85
Recurrent respiratory infections 7 | 141
Seizures 7 | 596
Skin Ulcer 7 | 48
Stomach Neoplasms 7 | 300
Sweating 7 | 81
Werner syndrome 7 | 29
Xerosis 7 | 75
colon cancer 7 | 1,478
juvenile dermatomyositis 7 | 1,187
non-small cell lung carcinoma 7 | 317
periodontitis 7 | 293
subependymal giant cell astrocytoma 7 | 2,287
Epilepsy 6 | 792
Failure to gain weight 6 | 365
Hemoglobin low 6 | 124
Pediatric failure to thrive 6 | 365
Prostate cancer 6 | 175
progressive supranuclear palsy 6 | 676
tuberculosis 6 | 2,010

Tissue

Endocrine System 81 | 18,159
Blood and immune system 80 | 16,909
Digestive Tract 80 | 17,369
Female tissues 80 | 17,400
Liver and Pancreas 80 | 16,750
Male tissues 80 | 17,142
Respiratory system 79 | 16,393
Skin and soft tissues 79 | 17,230
Urinary Tract 79 | 16,678
Nervous System 77 | 16,725
Cardiovascular System 76 | 15,192

Target Family

Non-IDG 47 | 12,091
Enzyme 21 | 4,145
Transcription Factor 8 | 1,400
Epigenetic 3 | 242
Kinase 2 | 634
GPCR 1 | 408

Compartment GO Term

chromosome, telomeric region 82 | 82
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA repair protein XRCC3 XRCC3 Tbio Non-IDG -2.50791 314.0 414
Telomerase protein component 1 TEP1 Tbio Enzyme -1.74492 50.6 71
TP53-binding protein 1 TP53BP1 Tbio Epigenetic -2.69485 464.8 577
Telomere repeats-binding bouquet formation protein 1 TERB1 Tdark Transcription Factor -0.45230 3.56 26
Telomerase-binding protein EST1A SMG6 Tbio Enzyme -1.48788 32.6 37
H/ACA ribonucleoprotein complex subunit 2 NHP2 Tbio Non-IDG -1.51951 28.7 54
Telomere length regulation protein TEL2 homolog TELO2 Tbio Non-IDG -0.93554 9.48 94
Structural maintenance of chromosomes protein 6 SMC6 Tbio Non-IDG -1.42371 20.0 115
Telomeric repeat-binding factor 2-interacting protein 1 TERF2IP Tchem Non-IDG -0.75509 5.75 308
CST complex subunit CTC1 CTC1 Tbio Non-IDG -1.74818 54.2 49