Development Level

Tbio 156 | 11,651
Tchem 23 | 1,388
Tdark 16 | 6,593
Tclin 3 | 612

IMPC Phenotype

preweaning lethality, complete... 37 | 979
embryonic lethality prior to o... 9 | 239
embryonic lethality prior to t... 8 | 278
preweaning lethality, incomple... 8 | 499
abnormal embryo size 6 | 220
embryonic growth retardation 5 | 106
abnormal tail morphology 4 | 25
cataract 4 | 92
increased circulating HDL chol... 4 | 80
abnormal behavior 3 | 298
abnormal bone structure 3 | 187
abnormal coat-hair pigmentatio... 3 | 64
abnormal lens morphology 3 | 81
abnormal seminal vesicle morph... 3 | 114
enlarged lymph nodes 3 | 37
increased bone mineral content 3 | 108
increased circulating alkaline... 3 | 122
increased fasted circulating g... 3 | 76
increased mean corpuscular vol... 3 | 92
abnormal behavioral response t... 2 | 66
abnormal craniofacial morpholo... 2 | 33
abnormal lung morphology 2 | 26
abnormal placenta size 2 | 20
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating choleste... 2 | 93
decreased circulating serum al... 2 | 82
decreased heart left ventricle... 2 | 28
decreased total body fat amoun... 2 | 207
edema 2 | 59
hemorrhage 2 | 23
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased circulating chloride... 2 | 41
increased circulating creatini... 2 | 38
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
small testis 2 | 58
vertebral fusion 2 | 23
abnormal cornea morphology 1 | 31
abnormal embryo turning 1 | 31
abnormal forebrain morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta morphology 1 | 5
abnormal placenta vasculature 1 | 2
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal rib morphology 1 | 10
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
cyanosis 1 | 7
decreased IgG1 level 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating chloride... 1 | 30
decreased circulating free fat... 1 | 31
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased mature B cell number 1 | 7
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
female infertility 1 | 60
hydrometra 1 | 53
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
irregularly shaped pupil 1 | 7
male infertility 1 | 123
microphthalmia 1 | 26
prenatal lethality prior to he... 1 | 87
respiratory system phenotype 1 | 2
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
small kidney 1 | 16
small spleen 1 | 19
syndactyly 1 | 23
urinary bladder obstruction 1 | 4
vertebral transformation 1 | 12

Disease

Carcinoma 126 | 11,493
ovarian cancer 126 | 8,520
medulloblastoma, large-cell 111 | 6,241
psoriasis 101 | 6,694
group 3 medulloblastoma 100 | 4,104
osteosarcoma 97 | 7,950
glioblastoma 95 | 5,792
lung cancer 92 | 4,740
atypical teratoid / rhabdoid tumor 90 | 5,112
Breast cancer 89 | 3,578
primitive neuroectodermal tumor 80 | 3,035
non-small cell lung cancer 68 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 67 | 3,291
ependymoma 65 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 63 | 2,989
adult high grade glioma 61 | 3,801
Cancer 60 | 2,499
adrenocortical carcinoma 60 | 1,428
malignant mesothelioma 60 | 3,232
lung adenocarcinoma 58 | 2,716
invasive ductal carcinoma 56 | 2,951
oligodendroglioma 43 | 2,850
Kidney cancer 41 | 2,613
ductal carcinoma in situ 41 | 1,745
colon cancer 39 | 1,478
pancreatic cancer 37 | 2,398
Endometriosis 35 | 540
astrocytic glioma 34 | 2,597
breast carcinoma 34 | 1,638
nasopharyngeal carcinoma 34 | 1,058
Atopic dermatitis 31 | 952
Waldenstrons macroglobulinemia 30 | 765
Astrocytoma, Pilocytic 28 | 3,081
Multiple myeloma 27 | 1,332
Pick disease 26 | 1,894
ulcerative colitis 25 | 1,819
Intellectual disability 24 | 1,016
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
subependymal giant cell astrocytoma 23 | 2,287
dermatomyositis 22 | 966
interstitial cystitis 20 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
Rheumatoid arthritis 19 | 1,191
pediatric high grade glioma 19 | 1,064
acute quadriplegic myopathy 16 | 1,158
astrocytoma 16 | 1,146
group 4 medulloblastoma 16 | 1,855
lung carcinoma 16 | 2,843
non primary Sjogren syndrome sicca 16 | 891
primary Sjogren syndrome 16 | 735
Cognitive delay 15 | 608
Global developmental delay 15 | 608
Mental and motor retardation 15 | 608
Short stature 15 | 531
juvenile dermatomyositis 15 | 1,187
pituitary cancer 15 | 1,972
tuberculosis 14 | 2,010
acute myeloid leukemia 13 | 783
Alzheimer's disease 12 | 658
Dull intelligence 12 | 645
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Poor school performance 12 | 645
Small head 12 | 374
Autosomal recessive predisposition 11 | 1,442
Hypoplastic mandible condyle 11 | 275
Mandibular hypoplasia 11 | 275
Micrognathism 11 | 275
Schizophrenia 11 | 1,160
progressive supranuclear palsy 11 | 676
Amyotrophic lateral sclerosis 10 | 451
Anteverted nostril 10 | 191
Epilepsy 10 | 792
diabetes mellitus 10 | 1,728
esophageal adenocarcinoma 10 | 737
Cryptorchidism 9 | 296
Liver cancer 9 | 604
Melanoma 9 | 711
Stomach Neoplasms 9 | 300
aldosterone-producing adenoma 9 | 665
medulloblastoma 9 | 720
Concave bridge of nose 8 | 195
Depressed nasal bridge 8 | 195
Depressed nasal root/bridge 8 | 195
Down syndrome 8 | 499
Microcephaly 8 | 166
Muscle hypotonia 8 | 571
Seizures 8 | 596
cutaneous lupus erythematosus 8 | 1,057
cystic fibrosis 8 | 1,696
gastric carcinoma 8 | 807
hepatocellular carcinoma 8 | 547
posterior fossa group A ependymoma 8 | 468
tuberculosis and treatment for 6 months 8 | 409
Congenital hypoplasia of penis 7 | 176
Prostatic Neoplasms 7 | 495
Short neck 7 | 140
gastric cancer 7 | 459
spina bifida 7 | 1,074

Tissue

Endocrine System 198 | 18,159
Male tissues 195 | 17,142
Skin and soft tissues 195 | 17,230
Digestive Tract 194 | 17,369
Female tissues 194 | 17,400
Blood and immune system 193 | 16,909
Respiratory system 193 | 16,393
Liver and Pancreas 192 | 16,750
Urinary Tract 192 | 16,678
Nervous System 191 | 16,725
Cardiovascular System 184 | 15,192

Target Family

Non-IDG 142 | 12,091
Enzyme 24 | 4,145
Kinase 12 | 634
Epigenetic 11 | 242
Transcription Factor 9 | 1,400

Compartment GO Term

chromosome, centromeric region 198 | 198
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Chromosome alignment-maintaining phosphoprotein 1 CHAMP1 Tbio Non-IDG -0.61730 4.58 106
Chromobox protein homolog 3 CBX3 Tbio Epigenetic -2.00023 90.5 366
Securin PTTG1 Tbio Non-IDG -2.42127 261.4 311
Protein ecdysoneless homolog ECD Tbio Non-IDG -0.72245 9.93 113
Cytoplasmic dynein 1 light intermediate chain 1 DYNC1LI1 Tbio Non-IDG -1.67860 45.9 100
Centromere protein O CENPO Tbio Non-IDG -0.67552 5.22 124
Dynactin subunit 5 DCTN5 Tdark Non-IDG -0.32495 0.71 53
Kinesin-like protein KIF22 KIF22 Tbio Non-IDG -1.69996 54.3 147
F-box only protein 28 FBXO28 Tbio Non-IDG -0.76212 5.60 144
Centromere/kinetochore protein zw10 homolog ZW10 Tbio Non-IDG -1.64269 41.5 124