Development Level

Tbio 145 | 10,625
Tchem 26 | 1,890
Tdark 22 | 7,003
Tclin 3 | 602

IMPC Phenotype

preweaning lethality, complete... 23 | 633
embryonic lethality prior to t... 7 | 187
embryonic lethality prior to o... 6 | 148
abnormal coat-hair pigmentatio... 3 | 54
abnormal embryo size 3 | 112
increased fasted circulating g... 3 | 68
increased sacral vertebrae num... 3 | 62
preweaning lethality, incomple... 3 | 260
abnormal behavior 2 | 226
abnormal forebrain development 2 | 18
abnormal hindbrain development 2 | 24
abnormal lens morphology 2 | 73
abnormal midbrain development 2 | 22
abnormal neural tube closure 2 | 37
abnormal placenta size 2 | 10
abnormal retina morphology 2 | 100
abnormal rib morphology 2 | 28
abnormal tail morphology 2 | 17
decreased basophil cell number 2 | 11
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased circulating serum al... 2 | 79
decreased eosinophil cell numb... 2 | 41
decreased lumbar vertebrae num... 2 | 62
decreased mean corpuscular hem... 2 | 34
decreased total body fat amoun... 2 | 186
embryonic growth retardation 2 | 28
enlarged lymph nodes 2 | 27
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased circulating alkaline... 2 | 119
increased circulating chloride... 2 | 43
increased circulating creatini... 2 | 29
increased circulating sodium l... 2 | 71
increased grip strength 2 | 83
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
vertebral fusion 2 | 23
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal craniofacial morpholo... 1 | 12
abnormal gait 1 | 51
abnormal kidney morphology 1 | 30
abnormal limb bud morphology 1 | 15
abnormal lung morphology 1 | 15
abnormal optic disc morphology 1 | 10
abnormal placenta morphology 1 | 4
abnormal placenta vasculature 1 | 2
abnormal spinal cord morpholog... 1 | 8
abnormal testis morphology 1 | 30
abnormal thoracic vertebrae mo... 1 | 16
cataract 1 | 26
craniofacial phenotype 1 | 9
cyanosis 1 | 6
decreased B cell number 1 | 30
decreased IgG1 level 1 | 4
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating LDL chol... 1 | 37
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating iron lev... 1 | 25
decreased circulating triglyce... 1 | 83
decreased effector memory CD4-... 1 | 6
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased lean body mass 1 | 195
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
edema 1 | 11
female infertility 1 | 34
hemorrhage 1 | 12
hydrops fetalis 1 | 22
hypoactivity 1 | 89
increased blood urea nitrogen ... 1 | 44
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating glucose ... 1 | 16
increased circulating total pr... 1 | 20
increased hematocrit 1 | 36
increased mean platelet volume 1 | 19
increased or absent threshold ... 1 | 128
increased red blood cell distr... 1 | 21
increased rib number 1 | 41
increased thermal nociceptive ... 1 | 9
increased thoracic vertebrae n... 1 | 8
narrow eye opening 1 | 15
polydactyly 1 | 22
respiratory system phenotype 1 | 2
shortened PQ interval 1 | 6
small testis 1 | 37
thrombocytopenia 1 | 46
tremors 1 | 34
urinary bladder obstruction 1 | 2
vertebral transformation 1 | 12

Disease

ovarian cancer 125 | 8,491
medulloblastoma, large-cell 107 | 6,234
psoriasis 100 | 6,685
osteosarcoma 95 | 7,933
glioblastoma 89 | 5,572
lung cancer 89 | 4,473
primitive neuroectodermal tumor 79 | 3,031
Breast cancer 77 | 3,098
group 3 medulloblastoma 70 | 2,254
pediatric high grade glioma 67 | 2,712
intraductal papillary-mucinous neoplasm (IPMN) 66 | 3,289
non-small cell lung cancer 66 | 2,798
atypical teratoid / rhabdoid tumor 64 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 61 | 2,988
malignant mesothelioma 59 | 3,163
adrenocortical carcinoma 57 | 1,427
lung adenocarcinoma 57 | 2,714
invasive ductal carcinoma 55 | 2,950
Cancer 52 | 2,346
oligodendroglioma 42 | 2,849
ductal carcinoma in situ 40 | 1,745
colon cancer 39 | 1,475
pancreatic cancer 34 | 2,300
Carcinoma 33 | 2,147
Endometriosis 33 | 535
nasopharyngeal carcinoma 33 | 1,056
breast carcinoma 32 | 1,614
posterior fossa group A ependymoma 32 | 1,511
astrocytic glioma 31 | 2,241
ependymoma 31 | 2,514
Atopic dermatitis 29 | 944
Waldenstrons macroglobulinemia 29 | 764
atypical teratoid/rhabdoid tumor 28 | 1,095
pilocytic astrocytoma 27 | 3,086
Multiple myeloma 26 | 1,327
Pick disease 26 | 1,893
IGA Glomerulonephritis 24 | 454
ulcerative colitis 24 | 2,087
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,956
sonic hedgehog group medulloblastoma 23 | 1,482
subependymal giant cell astrocytoma 23 | 2,287
dermatomyositis 22 | 966
Rheumatoid Arthritis 20 | 1,170
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,795
interstitial cystitis 19 | 2,299
Intellectual disability 17 | 573
astrocytoma 17 | 1,493
group 4 medulloblastoma 17 | 1,875
acute quadriplegic myopathy 16 | 1,157
lung carcinoma 16 | 2,844
primary Sjogren syndrome 16 | 788
juvenile dermatomyositis 15 | 1,189
medulloblastoma 15 | 1,524
non primary Sjogren syndrome sicca 15 | 840
pituitary cancer 14 | 1,972
acute myeloid leukemia 13 | 785
posterior fossa group B ependymoma 13 | 1,530
adult high grade glioma 11 | 2,148
inflammatory breast cancer 11 | 404
progressive supranuclear palsy 11 | 674
Alzheimer's disease 10 | 644
Down syndrome 10 | 548
diabetes mellitus 10 | 1,663
esophageal adenocarcinoma 10 | 737
aldosterone-producing adenoma 9 | 664
gastric carcinoma 9 | 832
tuberculosis 9 | 1,563
tuberculosis and treatment for 6 months 9 | 686
Amyotrophic Lateral Sclerosis 8 | 432
Microcephaly 8 | 149
Prostatic Neoplasms 8 | 471
Stomach Neoplasms 8 | 282
cutaneous lupus erythematosus 8 | 1,056
gastric cancer 8 | 436
hepatocellular carcinoma 8 | 550
Mammary Neoplasms 7 | 410
Roberts syndrome 7 | 16
cystic fibrosis 7 | 1,670
hereditary spastic paraplegia 7 | 313
non-small cell lung carcinoma 7 | 413
spina bifida 7 | 1,064
Adenoid Cystic Carcinoma 6 | 99
Cornelia de Lange syndrome 6 | 21
Infertility 6 | 163
Lupus erythematosus 6 | 80
Male infertility 6 | 170
Melanoma 6 | 261
Neurodegenerative disease 6 | 383
Schizophrenia 6 | 503
Systemic scleroderma 6 | 66
active Crohn's disease 6 | 918
pancreatic carcinoma 6 | 567
Acquired metabolic disease 5 | 267
Bladder Neoplasm 5 | 109
Colorectal Neoplasms 5 | 217
Peripheral Neuropathy 5 | 303
Polycystic Ovary Syndrome 5 | 334
cystic fibrosis and chronic rhinosinusitis 5 | 213
periodontitis 5 | 269
primary pancreatic ductal adenocarcinoma 5 | 1,271

Tissue

Blood and immune system 196 | 17,994
Digestive Tract 196 | 18,472
Endocrine System 196 | 18,511
Cardiovascular System 195 | 17,957
Female tissues 195 | 18,646
Male tissues 195 | 17,968
Nervous System 195 | 18,560
Skin and soft tissues 195 | 18,114
Urinary Tract 195 | 18,443
Liver and Pancreas 194 | 18,135
Respiratory system 193 | 17,483

Target Family

Non-IDG 141 | 11,969
Enzyme 24 | 4,146
Epigenetic 12 | 242
Kinase 12 | 634
Transcription Factor 7 | 1,400

Compartment GO Term

chromosome, centromeric region 196 | 196
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pyrin domain-containing protein 1 PYDC1 Tbio Non-IDG -2.87047 721.5 92
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.25806 19000.3 3336
Trafficking protein particle complex subunit 12 TRAPPC12 Tbio Non-IDG -0.28255 1.52 54
Tumor suppressor p53-binding protein 1 TP53BP1 Tbio Epigenetic -2.65153 422.5 514
Protein Mis18-beta OIP5 Tbio Non-IDG -1.17135 15.6 42
Histone-lysine N-methyltransferase SUV39H1 SUV39H1 Tchem Epigenetic -2.21810 149.4 267
Cat eye syndrome critical region protein 2 CECR2 Tchem Epigenetic -2.16064 142.8 42
Centromere protein X CENPX Tbio Non-IDG -0.76927 5.02 24
BUB3-interacting and GLEBS motif-containing protein ZNF207 ZNF207 Tbio Non-IDG -0.70005 4.45 248
Mitotic checkpoint serine/threonine-protein kinase BUB1 BUB1 Tchem Kinase -2.28810 192.8 356