Development Level

Tbio 111 | 11,445
Tchem 24 | 1,598
Tclin 12 | 613
Tdark 10 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 18 | 979
embryonic lethality prior to t... 6 | 278
abnormal embryo size 5 | 220
embryonic growth retardation 5 | 106
abnormal retina morphology 4 | 71
decreased body weight 4 | 161
edema 4 | 59
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
decreased circulating glucose ... 3 | 126
decreased leukocyte cell numbe... 3 | 73
decreased startle reflex 3 | 75
embryonic lethality prior to o... 3 | 239
hypoactivity 3 | 132
increased body weight 3 | 25
abnormal bone mineralization 2 | 38
abnormal pericardium morpholog... 2 | 26
decreased circulating choleste... 2 | 93
decreased circulating iron lev... 2 | 32
decreased circulating serum al... 2 | 82
decreased eosinophil cell numb... 2 | 24
decreased grip strength 2 | 116
decreased hematocrit 2 | 46
decreased lymphocyte cell numb... 2 | 83
decreased total body fat amoun... 2 | 207
increased blood urea nitrogen ... 2 | 48
increased bone mineral density 2 | 72
increased circulating choleste... 2 | 66
increased circulating triglyce... 2 | 42
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
absent teeth 1 | 3
brachydactyly 1 | 19
decreased NK cell number 1 | 2
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased mature B cell number 1 | 7
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased vertical activity 1 | 208
enlarged kidney 1 | 14
enlarged pancreas 1 | 2
enlarged spleen 1 | 41
hemorrhage 1 | 23
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
mydriasis 1 | 6
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened ST segment 1 | 10
small thymus 1 | 16
syndactyly 1 | 23
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 122 | 11,493
ovarian cancer 100 | 8,520
osteosarcoma 92 | 7,950
glioblastoma 79 | 5,792
psoriasis 67 | 6,694
Cancer 66 | 2,499
medulloblastoma, large-cell 63 | 6,241
lung cancer 60 | 4,740
non-small cell lung cancer 55 | 2,890
atypical teratoid / rhabdoid tumor 53 | 5,112
ependymoma 52 | 4,679
Breast cancer 48 | 3,578
Astrocytoma, Pilocytic 47 | 3,081
group 3 medulloblastoma 47 | 4,104
adult high grade glioma 46 | 3,801
invasive ductal carcinoma 46 | 2,951
pancreatic cancer 46 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 43 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 43 | 3,291
lung carcinoma 42 | 2,843
Kidney cancer 41 | 2,613
malignant mesothelioma 40 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 39 | 2,955
oligodendroglioma 38 | 2,850
subependymal giant cell astrocytoma 38 | 2,287
primitive neuroectodermal tumor 37 | 3,035
interstitial cystitis 35 | 2,312
lung adenocarcinoma 33 | 2,716
tuberculosis 31 | 2,010
astrocytic glioma 28 | 2,597
ulcerative colitis 28 | 1,819
Pick disease 27 | 1,894
astrocytoma 27 | 1,146
breast carcinoma 26 | 1,638
colon cancer 26 | 1,478
diabetes mellitus 26 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,962
cystic fibrosis 24 | 1,696
dermatomyositis 24 | 966
ductal carcinoma in situ 24 | 1,745
group 4 medulloblastoma 23 | 1,855
primary pancreatic ductal adenocarcinoma 23 | 1,109
adrenocortical carcinoma 22 | 1,428
Liver Cirrhosis, Experimental 21 | 769
juvenile dermatomyositis 21 | 1,187
acute quadriplegic myopathy 18 | 1,158
pituitary cancer 18 | 1,972
Intellectual disability 17 | 1,016
pediatric high grade glioma 17 | 1,064
Rheumatoid arthritis 16 | 1,191
spina bifida 16 | 1,074
Prostatic Neoplasms 15 | 495
Breast Neoplasms 14 | 445
Mammary Neoplasms 14 | 425
Neoplasm Invasiveness 14 | 161
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 510
gastric carcinoma 14 | 807
pancreatic carcinoma 14 | 562
Schizophrenia 13 | 1,160
Vascular disease 13 | 319
Autosomal recessive predisposition 12 | 1,442
Kidney disease 12 | 430
Melanoma 12 | 711
Stomach Neoplasms 12 | 300
active Crohn's disease 12 | 922
esophageal adenocarcinoma 12 | 737
primary Sjogren syndrome 12 | 735
Duchenne muscular dystrophy 11 | 601
Dull intelligence 11 | 645
Low intelligence 11 | 645
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Neoplasm Metastasis 11 | 168
Poor school performance 11 | 645
Waldenstrons macroglobulinemia 11 | 765
cutaneous lupus erythematosus 11 | 1,057
medulloblastoma 11 | 720
nasopharyngeal carcinoma 11 | 1,058
Carcinoma, Squamous Cell 10 | 110
Down syndrome 10 | 499
Multiple myeloma 10 | 1,332
Renal Cell Carcinoma 10 | 214
Short stature 10 | 531
Squamous cell carcinoma 10 | 129
fibroadenoma 10 | 559
Arthritis 9 | 290
Colorectal Neoplasms 9 | 243
Heart disease 9 | 306
Liver cancer 9 | 604
Skin cancer 9 | 469
gastric cancer 9 | 459
posterior fossa group A ependymoma 9 | 468
Bipolar Disorder 8 | 666
Cognitive delay 8 | 608
Global developmental delay 8 | 608
Lung disease 8 | 142
Mental and motor retardation 8 | 608
Osteoporosis 8 | 363
hereditary spastic paraplegia 8 | 318
non primary Sjogren syndrome sicca 8 | 891

Tissue

Endocrine System 155 | 18,159
Blood and immune system 154 | 16,909
Digestive Tract 154 | 17,369
Female tissues 154 | 17,400
Liver and Pancreas 154 | 16,750
Male tissues 154 | 17,142
Skin and soft tissues 154 | 17,230
Nervous System 153 | 16,725
Urinary Tract 153 | 16,678
Respiratory system 152 | 16,393
Cardiovascular System 149 | 15,192

Target Family

Non-IDG 100 | 12,091
Enzyme 24 | 4,145
Kinase 24 | 634
Transcription Factor 4 | 1,400
Epigenetic 2 | 242
GPCR 1 | 408
Ion Channel 1 | 344
Transporter 1 | 473

Compartment GO Term

cell-substrate adherens juncti... 157 | 157
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 ALKBH6 Tdark Enzyme 0.38 0.31 58
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Tensin-1 TNS1 Tbio Non-IDG -2.74141 354.5 133
LIM domain and actin-binding protein 1 LIMA1 Tbio Non-IDG -1.26880 23.6 187
Nebulin-related-anchoring protein NRAP Tbio Non-IDG -0.50644 3.42 54
Small muscular protein SMPX Tbio Non-IDG -1.24150 17.2 48
ARF GTPase-activating protein GIT1 GIT1 Tbio Enzyme -1.84352 75.7 358
Talin-2 TLN2 Tbio Non-IDG -1.36153 20.0 101