Development Level

Tbio 73 | 11,651
Tdark 5 | 6,593
Tchem 4 | 1,388

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
abnormal embryo size 2 | 220
abnormal retina morphology 2 | 71
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
increased lean body mass 2 | 172
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal coping response 1 | 1
abnormal craniofacial morpholo... 1 | 33
abnormal digestive system phys... 1 | 1
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating alanine ... 1 | 47
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating phosphat... 1 | 27
decreased coping response 1 | 8
decreased glycosylated hemoglo... 1 | 1
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
dilated heart left ventricle 1 | 11
edema 1 | 59
embryonic growth retardation 1 | 106
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
increased or absent threshold ... 1 | 101
increased vertical activity 1 | 24
male infertility 1 | 123
mammalian phenotype 1 | 17
pale yolk sac 1 | 25
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged ST segment 1 | 36
small testis 1 | 58
tremors 1 | 39

Disease

Carcinoma 60 | 11,493
ovarian cancer 51 | 8,520
glioblastoma 45 | 5,792
osteosarcoma 44 | 7,950
psoriasis 43 | 6,694
atypical teratoid / rhabdoid tumor 42 | 5,112
medulloblastoma, large-cell 41 | 6,241
ependymoma 38 | 4,679
lung cancer 34 | 4,740
Cancer 32 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,291
malignant mesothelioma 28 | 3,232
non-small cell lung cancer 28 | 2,890
interstitial cystitis 27 | 2,312
pancreatic cancer 27 | 2,398
Breast cancer 26 | 3,578
adult high grade glioma 26 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
lung adenocarcinoma 25 | 2,716
invasive ductal carcinoma 23 | 2,951
pituitary cancer 22 | 1,972
Kidney cancer 20 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
ductal carcinoma in situ 19 | 1,745
group 3 medulloblastoma 19 | 4,104
lung carcinoma 19 | 2,843
primitive neuroectodermal tumor 19 | 3,035
Astrocytoma, Pilocytic 18 | 3,081
subependymal giant cell astrocytoma 18 | 2,287
spina bifida 17 | 1,074
primary pancreatic ductal adenocarcinoma 16 | 1,109
breast carcinoma 15 | 1,638
group 4 medulloblastoma 15 | 1,855
astrocytic glioma 14 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
esophageal adenocarcinoma 13 | 737
oligodendroglioma 13 | 2,850
cystic fibrosis 12 | 1,696
ulcerative colitis 11 | 1,819
acute quadriplegic myopathy 10 | 1,158
colon cancer 10 | 1,478
diabetes mellitus 10 | 1,728
juvenile dermatomyositis 10 | 1,187
tuberculosis 10 | 2,010
Breast Neoplasms 9 | 445
Liver Cirrhosis, Experimental 9 | 769
dermatomyositis 9 | 966
Mammary Neoplasms 8 | 425
Prostatic Neoplasms 8 | 495
Rheumatoid arthritis 8 | 1,191
Waldenstrons macroglobulinemia 8 | 765
adrenocortical carcinoma 8 | 1,428
aldosterone-producing adenoma 8 | 665
Autosomal recessive predisposition 7 | 1,442
Cardiomyopathy 7 | 116
Duchenne muscular dystrophy 7 | 601
Melanoma 7 | 711
Neoplasm Invasiveness 7 | 161
astrocytoma 7 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
cutaneous lupus erythematosus 7 | 1,057
gastric carcinoma 7 | 807
pediatric high grade glioma 7 | 1,064
Atopic dermatitis 6 | 952
Cleft lip-palate-ectodermal dysplasia syndrome 6 | 8
Dilated cardiomyopathy 6 | 56
Down syndrome 6 | 499
Liver cancer 6 | 604
Osteoporosis 6 | 363
fibroadenoma 6 | 559
non primary Sjogren syndrome sicca 6 | 891
Alopecia 5 | 115
Amyotrophic lateral sclerosis 5 | 451
Arrhythmogenic right ventricular cardiomyopathy 5 | 30
Autistic Disorder 5 | 364
Becker muscular dystrophy 5 | 191
Endometrial cancer 5 | 311
Multiple Sclerosis 5 | 540
Multiple myeloma 5 | 1,332
Neoplasm Metastasis 5 | 168
Parkinson's disease 5 | 392
Pick disease 5 | 1,894
Skin cancer 5 | 469
active ulcerative colitis 5 | 764
acute myeloid leukemia 5 | 783
hereditary spastic paraplegia 5 | 318
limb girdle muscular dystrophy 2A 5 | 213
medulloblastoma 5 | 720
mucosa-associated lymphoid tissue lymphoma 5 | 484
posterior fossa group A ependymoma 5 | 468
Alzheimer's disease 4 | 658
Inflammatory bowel disease 4 | 151
Kidney disease 4 | 430
Prostate cancer 4 | 175
Schizophrenia 4 | 1,160
nasopharyngeal carcinoma 4 | 1,058
primary Sjogren syndrome 4 | 735
sonic hedgehog group medulloblastoma 4 | 467
tuberculosis and treatment for 3 months 4 | 179
urothelial carcinoma 4 | 318

Tissue

Blood and immune system 80 | 16,909
Digestive Tract 80 | 17,369
Endocrine System 79 | 18,159
Female tissues 79 | 17,400
Liver and Pancreas 79 | 16,750
Male tissues 79 | 17,142
Nervous System 79 | 16,725
Skin and soft tissues 79 | 17,230
Urinary Tract 79 | 16,678
Respiratory system 78 | 16,393
Cardiovascular System 73 | 15,192

Target Family

Non-IDG 71 | 12,091
Enzyme 8 | 4,145
Kinase 2 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

cell-cell adherens junction 82 | 82
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-cell immunoreceptor with Ig and ITIM domains TIGIT Tbio Non-IDG -1.72549 54.9 142
Tropomodulin-3 TMOD3 Tbio Non-IDG -1.07490 13.0 95
Actin-related protein 3 ACTR3 Tbio Non-IDG -1.28334 17.7 202
Cell adhesion molecule 1 CADM1 Tbio Non-IDG -2.77749 549.7 479
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit PPP1CA Tchem Enzyme -2.17010 139.0 378
Cell division cycle-associated protein 3 CDCA3 Tbio Non-IDG -0.69544 5.16 140
Fibroblast growth factor receptor substrate 2 FRS2 Tbio Non-IDG -2.37203 224.0 344
Nectin-4 NECTIN4 Tbio Non-IDG -2.04277 114.0 151
Poliovirus receptor PVR Tbio Non-IDG -3.43049 2640.6 432
Catenin alpha-3 CTNNA3 Tbio Non-IDG -1.63017 40.4 140