Development Level

Tbio 3 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

increased bone mineral density 2 | 72
preweaning lethality, complete... 2 | 979
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal head morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal startle reflex 1 | 15
decreased caudal vertebrae num... 1 | 53
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
decreased total body fat amoun... 1 | 207
increased bone mineral content 1 | 108
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 4 | 11,493
atypical teratoid / rhabdoid tumor 4 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pancreatic cancer 4 | 2,398
primitive neuroectodermal tumor 4 | 3,035
Neurodevelopmental Disorders 3 | 70
Schizophrenia 3 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
glioblastoma 3 | 5,792
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
psoriasis 3 | 6,694
Adenocarcinoma 2 | 122
Alopecia 2 | 115
Bipolar Disorder 2 | 666
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Colonic Neoplasms 2 | 142
Colorectal Neoplasms 2 | 243
Craniofacial Abnormalities 2 | 151
Duchenne muscular dystrophy 2 | 601
Hypoplasia of corpus callosum 2 | 90
Intellectual disability 2 | 1,016
Liver neoplasms 2 | 130
Melanoma 2 | 711
Muscle hypotonia 2 | 571
No-Reflow Phenomenon 2 | 3
Obesity 2 | 678
Pick disease 2 | 1,894
Prostatic Neoplasms 2 | 495
Rheumatoid arthritis 2 | 1,191
Skin cancer 2 | 469
Small head 2 | 374
Strabismus 2 | 270
astrocytic glioma 2 | 2,597
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pediatric high grade glioma 2 | 1,064
Abnormality of the musculature 1 | 16
Acquired flat foot 1 | 72
Adrenal Gland Neoplasms 1 | 11
Adrenal cortical adenocarcinoma 1 | 4
Adrenal gland cancer 1 | 12
Afro-textured hair 1 | 13
Ameloblastoma 1 | 24
Angiosarcoma 1 | 11
Biliary tract cancer 1 | 19
Bone cancer 1 | 16
Cardiomyopathy, right ventricular 1 | 7
Colorectal cancer 1 | 25
Curly hair (finding) 1 | 14
DOID:3858 1 | 6
DOID:8600 1 | 4
Flatfoot 1 | 73
Fragile skin 1 | 18
Heart Diseases 1 | 43
Hemangiosarcoma 1 | 18
Hepatoblastoma 1 | 19
Hepatocellular Adenoma 1 | 10
Hereditary nonpolyposis colorectal carcinoma 1 | 18
Hyperprolactinemia 1 | 27
Increased gastric cancer 1 | 21
Intestinal benign neoplasm 1 | 12
Kinky hair texture 1 | 13
LEOPARD syndrome 1 | 20
Leiomyosarcoma of uterus 1 | 13
Liver Neoplasms, Experimental 1 | 59
Malignant neoplasm of ovary 1 | 4
Micronodular cirrhosis 1 | 12
Nappy hair texture 1 | 13
Papilledema 1 | 11
Pilomatrixoma 1 | 12
Retroperitoneal cancer 1 | 4
Single transverse palmar crease 1 | 29
Sparse eyebrow 1 | 42
Sparse scalp hair 1 | 42
Stomach cancer 1 | 30
Subacute progressive viral hepatitis 1 | 9
Tachycardia, Ventricular 1 | 22
Transitional cell carcinoma of bladder 1 | 17
Uterine adnexa cancer 1 | 4
Widely spaced teeth 1 | 31
osteoporosis-pseudoglioma syndrome 1 | 9

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Non-IDG 2 | 12,091
Transcription Factor 2 | 1,400

Compartment GO Term

catenin-TCF7L2 complex 4 | 4
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Junction plakoglobin JUP Tbio Non-IDG -2.01808 101.8 719
Transcription factor 4 TCF4 Tbio Transcription Factor -2.57908 320.1 249
Catenin beta-1 CTNNB1 Tchem Non-IDG -3.99948 9786.0 3058
Transcription factor 7-like 2 TCF7L2 Tbio Transcription Factor -2.63620 474.2 327