Development Level

Tbio 9 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal kidney morphology 1 | 65
abnormal response to tactile s... 1 | 17
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased circulating triglyce... 1 | 79
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
prenatal lethality 1 | 28

Disease

ovarian cancer 7 | 8,520
Carcinoma 6 | 11,493
adult high grade glioma 4 | 3,801
osteosarcoma 4 | 7,950
pancreatic cancer 4 | 2,398
astrocytic glioma 3 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung cancer 3 | 4,740
psoriasis 3 | 6,694
subependymal giant cell astrocytoma 3 | 2,287
Bilateral fifth finger clinodactyly 2 | 110
Brachycephaly 2 | 88
Brachydactyly 2 | 156
Breast cancer 2 | 3,578
Broad cranium shape 2 | 88
Broad forehead 2 | 59
Cancer 2 | 2,499
Concave bridge of nose 2 | 195
Curvature of little finger 2 | 110
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Frontal bossing 2 | 157
Multiple myeloma 2 | 1,332
Orbital separation excessive 2 | 244
Short stature 2 | 531
Strabismus 2 | 270
Syndactyly of the toes 2 | 45
Wide skull shape 2 | 88
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
malignant mesothelioma 2 | 3,232
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010
Acquired flat foot 1 | 72
Acrocephaly 1 | 12
Asymmetry of the posterior cranium 1 | 20
Autosomal recessive Robinow syndrome 1 | 27
Bejel 1 | 5
Bunion 1 | 26
Cellulitis 1 | 20
Convex nasal bridge 1 | 57
Convex nasal ridge 1 | 37
Coronal craniosynostosis 1 | 14
Decreased pain sensation 1 | 17
Decreased projection of maxilla 1 | 66
Decreased projection of midface 1 | 105
Deficiency of upper jaw bones 1 | 66
Epidermolysis bullosa acquisita 1 | 10
Ewing sarcoma 1 | 25
Exocrine pancreatic insufficiency 1 | 32
Facial asymmetry 1 | 32
Fatty liver disease 1 | 103
Flat forehead 1 | 5
Flatfoot 1 | 73
Flattening of cranial vault 1 | 20
Flattening of head 1 | 20
Hallux Valgus 1 | 26
Hoarseness 1 | 31
Hyperacusis 1 | 11
Hypertriglyceridemia result 1 | 37
Hypotrophic midface 1 | 105
Intestinal volvulus 1 | 8
Large elongated pulp chamber 1 | 14
Legionnaires' disease 1 | 20
Lordosis 1 | 54
Melioidosis 1 | 17
Midface retrusion 1 | 105
Mitral valve insufficiency 1 | 49
Mitral valve prolapse 1 | 14
Narrow nose 1 | 20
Narrow palate 1 | 20
Neuroectodermal tumor 1 | 3
Open Bite 1 | 21
Open mouth 1 | 45
Osteochondrosis 1 | 17
Pancreatitis 1 | 123
Plagiocephaly 1 | 20
Plagiocephaly, Nonsynostotic 1 | 20
Prominent nasal bridge 1 | 57
Rhomboid shaped head 1 | 20
Saethre-Chotzen syndrome 1 | 7
Sarcoma 1 | 62
Self-Injurious Behavior 1 | 12
Serum cholesterol raised 1 | 22
Shallow orbits 1 | 13
Small midface 1 | 105
Smith-Magenis syndrome 1 | 29
Spinocerebellar ataxia type 17 1 | 7
Syndactyly of fingers 1 | 48
Synostotic Posterior Plagiocephaly 1 | 8
Taurodontism 1 | 14
Typhoid fever 1 | 22
Werner syndrome 1 | 29
alcohol-related neurodevelopmental disorder 1 | 13

Tissue

Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Cardiovascular System 8 | 15,192
Nervous System 8 | 16,725

Target Family

Non-IDG 4 | 12,091
Enzyme 3 | 4,145
Transcription Factor 2 | 1,400

Compartment GO Term

bacterial-type flagellum part 9 | 9
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein fem-1 homolog B FEM1B Tbio Non-IDG -1.23011 18.1 144
ATPase WRNIP1 WRNIP1 Tbio Enzyme -2.55209 340.4 166
Chymotrypsin-like elastase family member 3A CELA3A Tbio Enzyme -1.29735 18.6 127
Nuclear transcription factor Y subunit beta NFYB Tbio Transcription Factor -2.06047 104.8 207
Twist-related protein 1 TWIST1 Tbio Transcription Factor -3.91883 8025.6 425
Huntingtin-associated protein 1 HAP1 Tbio Non-IDG -1.91793 84.1 162
Protein flightless-1 homolog FLII Tbio Non-IDG -2.41908 275.7 92
E3 ubiquitin-protein ligase KCMF1 KCMF1 Tbio Enzyme -1.35873 21.1 100
Toll-like receptor 5 TLR5 Tbio Non-IDG -2.79280 635.6 691