Development Level

Tbio 33 | 11,445
Tchem 6 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 11 | 979
embryonic lethality prior to o... 5 | 239
embryonic lethality prior to t... 5 | 278
abnormal embryo size 4 | 220
abnormal bone structure 3 | 187
embryonic growth retardation 3 | 106
abnormal heart morphology 2 | 162
abnormal placenta size 2 | 20
anophthalmia 2 | 33
female infertility 2 | 60
increased circulating HDL chol... 2 | 80
increased mean corpuscular vol... 2 | 92
male infertility 2 | 123
abnormal craniofacial morpholo... 1 | 33
abnormal forebrain morphology 1 | 10
abnormal head shape 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta morphology 1 | 5
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
brachydactyly 1 | 19
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating glucose ... 1 | 126
decreased mean corpuscular hem... 1 | 50
edema 1 | 59
enlarged heart 1 | 210
impaired glucose tolerance 1 | 75
increased basophil cell number 1 | 7
increased bone mineral content 1 | 108
increased circulating alanine ... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
microphthalmia 1 | 26
pallor 1 | 34
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
small kidney 1 | 16
small spleen 1 | 19
small testis 1 | 58
syndactyly 1 | 23
urinary bladder obstruction 1 | 4

Disease

ovarian cancer 26 | 8,520
Carcinoma 23 | 11,493
glioblastoma 23 | 5,792
medulloblastoma, large-cell 22 | 6,241
osteosarcoma 21 | 7,950
psoriasis 21 | 6,694
atypical teratoid / rhabdoid tumor 20 | 5,112
Cancer 19 | 2,499
lung cancer 18 | 4,740
Breast cancer 17 | 3,578
group 3 medulloblastoma 16 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
adrenocortical carcinoma 15 | 1,428
invasive ductal carcinoma 14 | 2,951
malignant mesothelioma 14 | 3,232
non-small cell lung cancer 14 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
adult high grade glioma 12 | 3,801
lung adenocarcinoma 12 | 2,716
primitive neuroectodermal tumor 12 | 3,035
Atopic dermatitis 10 | 952
Endometriosis 10 | 540
colon cancer 10 | 1,478
breast carcinoma 9 | 1,638
ductal carcinoma in situ 9 | 1,745
pancreatic cancer 9 | 2,398
ependymoma 8 | 4,679
Intellectual disability 7 | 1,016
Kidney cancer 7 | 2,613
nasopharyngeal carcinoma 7 | 1,058
Short stature 6 | 531
primary Sjogren syndrome 6 | 735
Cognitive delay 5 | 608
Dull intelligence 5 | 645
Global developmental delay 5 | 608
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Multiple myeloma 5 | 1,332
Poor school performance 5 | 645
Small head 5 | 374
Waldenstrons macroglobulinemia 5 | 765
astrocytoma 5 | 1,146
esophageal adenocarcinoma 5 | 737
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
medulloblastoma 5 | 720
oligodendroglioma 5 | 2,850
posterior fossa group A ependymoma 5 | 468
ulcerative colitis 5 | 1,819
Glaucoma 4 | 239
Hypoplastic mandible condyle 4 | 275
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Pick disease 4 | 1,894
Triangular face 4 | 58
acute quadriplegic myopathy 4 | 1,158
astrocytic glioma 4 | 2,597
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
pediatric high grade glioma 4 | 1,064
primary pancreatic ductal adenocarcinoma 4 | 1,109
Abnormality of vision 3 | 40
Abnormally small eyeball 3 | 97
Acquired metabolic disease 3 | 336
Ascites 3 | 22
Autosomal recessive predisposition 3 | 1,442
Cataract 3 | 297
Clouding of corneal stroma 3 | 50
Congenital Epicanthus 3 | 177
Corneal Opacity 3 | 53
Dandy-Walker Syndrome 3 | 39
Decreased size of eyeball 3 | 97
Fetal Growth Retardation 3 | 189
Increased nuchal translucency 3 | 6
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Lens Opacities 3 | 231
MOSAIC VARIEGATED ANEUPLOIDY SYNDROME 3 | 5
Microphthalmos 3 | 100
Muscle biopsy shows dystrophic changes 3 | 39
Muscular dystrophy 3 | 75
Neuronal ceroid lipofuscinosis 2 3 | 17
Parkinson's disease 3 | 392
Penile hypospadias 3 | 106
Polyhydramnios 3 | 108
Postnatal growth retardation 3 | 57
Renal Cell Carcinoma 3 | 214
dermatomyositis 3 | 966
mosaic variegated aneuploidy syndrome 1 3 | 4
non primary Sjogren syndrome sicca 3 | 891
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
Astrocytoma, Pilocytic 2 | 3,081
Bipolar Disorder 2 | 666
Polycystic ovary syndrome 2 | 360
fibroadenoma 2 | 559
mucosa-associated lymphoid tissue lymphoma 2 | 484
sonic hedgehog group medulloblastoma 2 | 467
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Blood and immune system 41 | 16,909
Digestive Tract 41 | 17,369
Endocrine System 41 | 18,159
Female tissues 41 | 17,400
Male tissues 41 | 17,142
Skin and soft tissues 41 | 17,230
Liver and Pancreas 40 | 16,750
Nervous System 40 | 16,725
Respiratory system 40 | 16,393
Urinary Tract 40 | 16,678
Cardiovascular System 39 | 15,192

Target Family

Non-IDG 20 | 12,091
Enzyme 15 | 4,145
Kinase 6 | 634

Compartment GO Term

anaphase-promoting complex 41 | 41
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Anaphase-promoting complex subunit 10 ANAPC10 Tbio Enzyme -1.23751 18.1 156
Anaphase-promoting complex subunit 11 ANAPC11 Tbio Enzyme -1.27406 17.9 239
Anaphase-promoting complex subunit 2 ANAPC2 Tbio Enzyme -0.45557 2.44 166
Anaphase-promoting complex subunit 4 ANAPC4 Tbio Enzyme 0.43 0.13 156
Anaphase-promoting complex subunit 7 ANAPC7 Tbio Enzyme -0.17118 1.40 73
Cell division cycle protein 23 homolog CDC23 Tbio Non-IDG -1.50528 30.4 191
Cullin-7 CUL7 Tbio Non-IDG -1.49747 38.0 139
Anaphase-promoting complex subunit 15 ANAPC15 Tdark Enzyme -0.41378 2.22 27
Ubiquitin-conjugating enzyme E2 C UBE2C Tbio Non-IDG -1.93680 92.1 352
Ubiquitin-conjugating enzyme E2 S UBE2S Tbio Non-IDG -2.36597 158.3 384