Development Level

Tbio 132 | 11,445
Tchem 15 | 1,598
Tclin 10 | 613
Tdark 8 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal behavior 6 | 298
increased or absent threshold ... 6 | 101
preweaning lethality, incomple... 6 | 499
increased circulating sodium l... 5 | 71
abnormal retina morphology 3 | 71
absent pinna reflex 3 | 23
absent startle reflex 3 | 24
decreased grip strength 3 | 116
decreased prepulse inhibition 3 | 82
embryonic lethality prior to t... 3 | 278
hyperactivity 3 | 148
increased lean body mass 3 | 172
abnormal coat-hair pigmentatio... 2 | 64
abnormal cornea morphology 2 | 31
abnormal embryo size 2 | 220
abnormal pericardium morpholog... 2 | 26
abnormal vibrissa morphology 2 | 25
decreased body weight 2 | 161
decreased circulating amylase ... 2 | 28
decreased circulating creatini... 2 | 39
decreased circulating free fat... 2 | 31
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased startle reflex 2 | 75
decreased threshold for audito... 2 | 26
decreased total body fat amoun... 2 | 207
impaired righting response 2 | 26
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased circulating calcium ... 2 | 34
increased thermal nociceptive ... 2 | 9
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
persistence of hyaloid vascula... 2 | 33
small testis 2 | 58
stereotypic behavior 2 | 3
trunk curl 2 | 16
abnormal behavioral response t... 1 | 66
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal digit morphology 1 | 10
abnormal ear morphology 1 | 9
abnormal embryo turning 1 | 31
abnormal femur morphology 1 | 14
abnormal hair growth 1 | 10
abnormal iris morphology 1 | 13
abnormal locomotor activation 1 | 16
abnormal locomotor behavior 1 | 24
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
absent vibrissae 1 | 12
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased hemoglobin content 1 | 68
decreased spleen weight 1 | 10
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
fused cornea and lens 1 | 5
fused phalanges 1 | 1
hydrometra 1 | 53
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased spleen weight 1 | 10
increased vertical activity 1 | 24
pallor 1 | 34
polycystic kidney 1 | 15
short tibia 1 | 97
tremors 1 | 39

Disease

Carcinoma 128 | 11,493
ovarian cancer 89 | 8,520
psoriasis 82 | 6,694
osteosarcoma 81 | 7,950
medulloblastoma, large-cell 67 | 6,241
glioblastoma 66 | 5,792
lung cancer 56 | 4,740
Cancer 55 | 2,499
ependymoma 55 | 4,679
atypical teratoid / rhabdoid tumor 54 | 5,112
Breast cancer 52 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 49 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 49 | 2,989
malignant mesothelioma 46 | 3,232
adult high grade glioma 43 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 43 | 3,291
pancreatic cancer 43 | 2,398
Kidney cancer 42 | 2,613
invasive ductal carcinoma 40 | 2,951
non-small cell lung cancer 40 | 2,890
Astrocytoma, Pilocytic 39 | 3,081
lung adenocarcinoma 39 | 2,716
lung carcinoma 39 | 2,843
group 3 medulloblastoma 37 | 4,104
colon cancer 33 | 1,478
interstitial cystitis 32 | 2,312
Nonsyndromic deafness 31 | 142
cystic fibrosis 31 | 1,696
Autosomal recessive predisposition 30 | 1,442
astrocytic glioma 29 | 2,597
diabetes mellitus 29 | 1,728
ductal carcinoma in situ 29 | 1,745
primitive neuroectodermal tumor 29 | 3,035
oligodendroglioma 27 | 2,850
subependymal giant cell astrocytoma 27 | 2,287
ulcerative colitis 27 | 1,819
breast carcinoma 26 | 1,638
acute quadriplegic myopathy 24 | 1,158
group 4 medulloblastoma 24 | 1,855
pituitary cancer 24 | 1,972
tuberculosis 24 | 2,010
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,962
Schizophrenia 22 | 1,160
juvenile dermatomyositis 19 | 1,187
primary pancreatic ductal adenocarcinoma 18 | 1,109
Intellectual disability 16 | 1,016
Liver Cirrhosis, Experimental 16 | 769
Liver cancer 16 | 604
Pick disease 16 | 1,894
astrocytoma 16 | 1,146
esophageal adenocarcinoma 16 | 737
dermatomyositis 15 | 966
Dull intelligence 14 | 645
Hypertension 14 | 396
Low intelligence 14 | 645
Melanoma 14 | 711
Mental Retardation 14 | 645
Mental deficiency 14 | 645
Poor school performance 14 | 645
Sensorineural Hearing Loss (disorder) 14 | 284
Sensorineural hearing loss 14 | 106
Skin cancer 14 | 469
adrenocortical carcinoma 14 | 1,428
nasopharyngeal carcinoma 14 | 1,058
pediatric high grade glioma 14 | 1,064
spina bifida 14 | 1,074
Cerebrovascular disease 13 | 238
Duchenne muscular dystrophy 13 | 601
Kidney disease 13 | 430
Rheumatoid arthritis 13 | 1,191
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 510
gastric carcinoma 13 | 807
Cataract 12 | 297
Cognitive delay 12 | 608
Down syndrome 12 | 499
Global developmental delay 12 | 608
Mental and motor retardation 12 | 608
Usher syndrome 12 | 32
active Crohn's disease 12 | 922
Alzheimer's disease 11 | 658
Asthma 11 | 385
Heart disease 11 | 306
Lens Opacities 11 | 231
Multiple myeloma 11 | 1,332
Obesity 11 | 678
active ulcerative colitis 11 | 764
mucosa-associated lymphoid tissue lymphoma 11 | 484
Endometriosis 10 | 540
Epilepsy 10 | 792
Myopathy 10 | 185
Neuropathy 10 | 261
Prostatic Neoplasms 10 | 495
Retinitis Pigmentosa 10 | 226
aldosterone-producing adenoma 10 | 665
Atherosclerosis 9 | 291
Muscle hypotonia 9 | 571
cutaneous lupus erythematosus 9 | 1,057
nephrosclerosis 9 | 333
non primary Sjogren syndrome sicca 9 | 891
pancreatic carcinoma 9 | 562

Tissue

Endocrine System 161 | 18,159
Digestive Tract 160 | 17,369
Female tissues 160 | 17,400
Male tissues 158 | 17,142
Skin and soft tissues 158 | 17,230
Liver and Pancreas 157 | 16,750
Blood and immune system 155 | 16,909
Nervous System 154 | 16,725
Urinary Tract 153 | 16,678
Respiratory system 150 | 16,393
Cardiovascular System 142 | 15,192

Target Family

Non-IDG 123 | 12,091
Enzyme 25 | 4,145
Kinase 6 | 634
Transporter 6 | 473
Ion Channel 3 | 344
Epigenetic 1 | 242
GPCR 1 | 408

Compartment GO Term

actin-based cell projection 165 | 165
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutaredoxin domain-containing cysteine-rich protein 2 GRXCR2 Tbio Non-IDG 0.00000 1.00 14
Neuromodulin GAP43 Tbio Non-IDG -2.93905 762.9 597
Unconventional myosin-XV MYO15A Tbio Non-IDG -1.64094 42.8 15
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Glutaredoxin domain-containing cysteine-rich protein 1 GRXCR1 Tdark Non-IDG -0.45230 3.09 43