Development Level

Tbio 127 | 11,178
Tchem 17 | 1,885
Tclin 10 | 612
Tdark 8 | 6,569

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal behavior 6 | 298
increased or absent threshold ... 6 | 101
preweaning lethality, incomple... 6 | 499
increased circulating sodium l... 5 | 71
abnormal retina morphology 3 | 71
absent pinna reflex 3 | 23
absent startle reflex 3 | 24
decreased grip strength 3 | 116
decreased prepulse inhibition 3 | 82
embryonic lethality prior to t... 3 | 278
hyperactivity 3 | 148
increased lean body mass 3 | 172
abnormal coat-hair pigmentatio... 2 | 64
abnormal cornea morphology 2 | 31
abnormal embryo size 2 | 220
abnormal pericardium morpholog... 2 | 26
abnormal vibrissa morphology 2 | 25
decreased body weight 2 | 161
decreased circulating amylase ... 2 | 28
decreased circulating creatini... 2 | 39
decreased circulating free fat... 2 | 31
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased startle reflex 2 | 75
decreased threshold for audito... 2 | 26
decreased total body fat amoun... 2 | 207
impaired righting response 2 | 26
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased circulating calcium ... 2 | 34
increased thermal nociceptive ... 2 | 9
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
persistence of hyaloid vascula... 2 | 33
small testis 2 | 58
stereotypic behavior 2 | 3
trunk curl 2 | 16
abnormal behavioral response t... 1 | 66
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal digit morphology 1 | 10
abnormal ear morphology 1 | 9
abnormal embryo turning 1 | 31
abnormal femur morphology 1 | 14
abnormal hair growth 1 | 10
abnormal iris morphology 1 | 13
abnormal locomotor activation 1 | 16
abnormal locomotor behavior 1 | 24
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
absent vibrissae 1 | 12
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased hemoglobin content 1 | 68
decreased spleen weight 1 | 10
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
fused cornea and lens 1 | 5
fused phalanges 1 | 1
hydrometra 1 | 53
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased spleen weight 1 | 10
increased vertical activity 1 | 24
pallor 1 | 34
polycystic kidney 1 | 15
short tibia 1 | 97
tremors 1 | 39

Disease

Carcinoma 125 | 11,192
ovarian cancer 88 | 8,297
osteosarcoma 81 | 7,766
psoriasis 81 | 6,514
medulloblastoma, large-cell 67 | 6,086
glioblastoma 66 | 5,635
ependymoma 55 | 4,559
lung cancer 55 | 4,607
Cancer 54 | 2,388
atypical teratoid / rhabdoid tumor 53 | 4,971
Breast cancer 51 | 3,469
intraductal papillary-mucinous carcinoma (IPMC) 48 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 47 | 2,872
malignant mesothelioma 45 | 3,135
adult high grade glioma 43 | 3,701
intraductal papillary-mucinous neoplasm (IPMN) 42 | 3,204
pancreatic cancer 42 | 2,322
Kidney cancer 40 | 2,548
invasive ductal carcinoma 40 | 2,867
Astrocytoma, Pilocytic 39 | 3,006
lung adenocarcinoma 39 | 2,627
non-small cell lung cancer 39 | 2,799
lung carcinoma 38 | 2,755
group 3 medulloblastoma 37 | 4,002
colon cancer 32 | 1,428
interstitial cystitis 32 | 2,237
Nonsyndromic deafness 31 | 137
cystic fibrosis 30 | 1,629
Autosomal recessive predisposition 29 | 1,407
astrocytic glioma 29 | 2,530
diabetes mellitus 29 | 1,683
primitive neuroectodermal tumor 29 | 2,957
ductal carcinoma in situ 28 | 1,686
oligodendroglioma 27 | 2,768
subependymal giant cell astrocytoma 27 | 2,230
ulcerative colitis 26 | 1,765
breast carcinoma 25 | 1,589
acute quadriplegic myopathy 24 | 1,133
group 4 medulloblastoma 24 | 1,806
pituitary cancer 24 | 1,915
tuberculosis 24 | 1,963
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,911
Schizophrenia 22 | 1,136
juvenile dermatomyositis 19 | 1,147
primary pancreatic ductal adenocarcinoma 17 | 1,071
Intellectual disability 16 | 998
Liver Cirrhosis, Experimental 16 | 733
Liver cancer 16 | 589
Pick disease 16 | 1,856
astrocytoma 16 | 1,113
esophageal adenocarcinoma 16 | 696
dermatomyositis 15 | 941
Dull intelligence 14 | 634
Hypertension 14 | 372
Low intelligence 14 | 634
Mental Retardation 14 | 634
Mental deficiency 14 | 634
Poor school performance 14 | 634
Sensorineural Hearing Loss (disorder) 14 | 281
Sensorineural hearing loss 14 | 102
adrenocortical carcinoma 14 | 1,385
nasopharyngeal carcinoma 14 | 1,024
pediatric high grade glioma 14 | 1,035
spina bifida 14 | 1,053
Cerebrovascular disease 13 | 223
Duchenne muscular dystrophy 13 | 587
Kidney disease 13 | 411
Melanoma 13 | 689
Rheumatoid arthritis 13 | 1,156
Skin cancer 13 | 451
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 492
gastric carcinoma 13 | 781
Cataract 12 | 290
Cognitive delay 12 | 596
Down syndrome 12 | 480
Global developmental delay 12 | 596
Mental and motor retardation 12 | 596
Usher syndrome 12 | 32
Alzheimer's disease 11 | 640
Asthma 11 | 370
Heart disease 11 | 288
Lens Opacities 11 | 227
Multiple myeloma 11 | 1,296
active ulcerative colitis 11 | 736
mucosa-associated lymphoid tissue lymphoma 11 | 473
Endometriosis 10 | 521
Epilepsy 10 | 775
Myopathy 10 | 185
Neuropathy 10 | 254
Obesity 10 | 655
Prostatic Neoplasms 10 | 472
Retinitis Pigmentosa 10 | 223
active Crohn's disease 10 | 882
aldosterone-producing adenoma 10 | 646
Atherosclerosis 9 | 276
Coronary artery disease 9 | 253
Muscle hypotonia 9 | 562
cutaneous lupus erythematosus 9 | 1,016
non primary Sjogren syndrome sicca 9 | 861
pancreatic carcinoma 9 | 555

Tissue

Endocrine System 158 | 18,159
Digestive Tract 157 | 17,369
Female tissues 157 | 17,400
Male tissues 156 | 17,142
Skin and soft tissues 156 | 17,230
Liver and Pancreas 155 | 16,750
Blood and immune system 152 | 16,909
Nervous System 152 | 16,725
Urinary Tract 151 | 16,678
Respiratory system 148 | 16,393
Cardiovascular System 140 | 15,192

Target Family

Non-IDG 122 | 12,091
Enzyme 23 | 4,145
Kinase 6 | 634
Transporter 6 | 473
Ion Channel 3 | 344
Epigenetic 1 | 242
GPCR 1 | 408

Compartment GO Term

actin-based cell projection 162 | 162
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dystroglycan DAG1 Tbio Enzyme -2.77503 560.0 254
Prominin-2 PROM2 Tbio Non-IDG -1.12562 11.0 199
Vinculin VCL Tbio Non-IDG -3.34872 2107.1 637
Transmembrane channel-like protein 2 TMC2 Tbio Ion Channel -1.19934 15.1 35
Whirlin WHRN Tbio Non-IDG -1.74958 54.1 123
Utrophin UTRN Tbio Non-IDG -2.63658 425.0 37
Carbonic anhydrase 9 CA9 Tclin Enzyme -3.00861 1024.2 742
Platelet-derived growth factor subunit A PDGFA Tchem Non-IDG -2.74845 537.8 341
Protein enabled homolog ENAH Tbio Non-IDG -1.02502 9.91 150
Coxsackievirus and adenovirus receptor CXADR Tbio Non-IDG -2.47204 284.9 320